Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029713 (immaturity)
4,335 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Apophyseal injuries, which are unique in the adolescent athlete, cause inflammation at the site of a major tendinous insertion onto a growing bony prominence. These injuries typically occur in active adolescents between the ages of eight and 15 years and usually present as periarticular pain associated with growth, skeletal immaturity, repetitive microtrauma and muscle-tendon imbalance. Common apophyseal injuries, and their sites, include Sever's disease (posterior calcaneus), Osgood-Schlatter disease (tibial tuberosity), Sindig-Larsen-Johansson syndrome (inferior patella), medial epicondylitis (humeral medial epicondyle) and apophysitis of the hip (iliac crest, ischial tuberosity). Conservative therapy, including rest, ice, compression, elevation, nonsteroidal anti-inflammatory agents, modification of the athlete's activity level and exercises for increased flexibility and strengthening, is usually effective.
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PMID:Apophyseal injuries in the young athlete. 776 80

In brief Because of their skeletal immaturity, children and adolescents are subject to a somewhat different set of overuse knee injuries than are adults. Described here are the diagnosis and treatment for the most common growth-related causes of knee pain in active young people: Osgood-Schlatter disease, Sinding-Larsen-Johansson disease, osteochondritis dissecans, bipartite patella, medial plica syndrome, and discoid meniscus. In most cases these conditions respond to conservative treatment.
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PMID:Overuse Knee Injuries in Young Athletes. 2743 99