Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0029463 (
osteosarcoma
)
16,637
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
osteosarcoma
14617
Sep
1084
Mol
969
p53
755
alkaline phosphatase
614
HOS
447
osteogenic
440
rhabdomyosarcoma
418
ROS
393
caspase-3
393
collagen
376
osteocalcin
310
Bcl-2
240
AKT
233
parathyroid hormone
225
p21
206
catenin
197
PI3K
189
PTH
174
cytokine
172
pRb
171
vimentin
154
mTOR
144
matrix metalloproteinase
138
fibronectin
137
vascular endothelial growth factor
134
adenylate cyclase
134
MRI
123
endoplasmic reticulum
121
ERK
120
ATP
118
cyclin D1
118
UTR
115
insulin
114
p38
114
MAPK
113
ERK1
112
osteopontin
111
She
111
PARP
109
MMP-9
109
annexin V
104
interferon
104
MMP-2
103
caspase-9
100
MDM2
99
histone
95
P-glycoprotein
93
E-cadherin
88
tumor necrosis factor
87
IL-6
85
cytochrome c
84
kit
82
insulin-like growth factor
82
MTX
82
type I collagen
81
CCK
80
JNK
80
VEGF
79
bone morphogenetic protein
79
glycoprotein
78
STAT3
77
NMR
76
c-fos
76
caspase-8
74
epidermal growth factor
73
fused
72
Fas
72
MMP9
71
proliferating cell nuclear antigen
69
TNF
67
parathyroid hormone-related protein
66
tyrosine kinase
66
vitamin D receptor
66
RUNX2
65
AS1
65
c-myc
65
osteonectin
65
c-Myc
64
cyclin
63
more...
Disease
osteosarcoma
16637
tumor
6675
cancer
5588
Osteosarcoma
2200
Osteosarcoma
2200
metastases
1656
sarcoma
1190
Ewing's sarcoma
830
chondrosarcoma
701
tumor growth
699
carcinoma
613
tumorigenesis
560
HOS
448
primary tumor
426
rhabdomyosarcoma
414
breast cancer
388
melanoma
385
fibrosarcoma
362
leukemia
340
tumor progression
337
bone cancer
327
lung metastases
316
retinoblastoma
307
neuroblastoma
290
lymphoma
260
metastatic osteosarcoma
258
adenocarcinoma
258
malignant fibrous histiocytoma
257
carcinogenesis
212
dysplasia
197
hepatocellular carcinoma
187
WT1
158
liposarcoma
156
leiomyosarcoma
154
Hodgkin's disease
148
lung cancer
147
squamous cell carcinoma
144
prostate cancer
143
osteoporosis
142
Sarcoma
138
Sarcoma
138
synovial sarcoma
131
multiple myeloma
130
angiosarcoma
124
glioma
119
PDB
118
osteochondroma
107
osteoma
106
fibroma
106
bone metastases
94
pathological fracture
94
aggressiveness
90
childhood cancer
89
MCF
86
colon cancer
85
renal cell carcinoma
85
acute lymphoblastic leukemia
83
osteoblastic osteosarcoma
80
chordoma
79
chondroblastoma
78
myositis
78
carcinosarcoma
76
lung carcinoma
74
ovarian cancer
71
Extraskeletal osteosarcoma
70
gastric cancer
69
acute myeloid leukemia
68
DDP
68
colorectal cancer
66
glioblastoma
65
AS1
65
solid tumor
64
osteomyelitis
63
chondroblastic osteosarcoma
63
SDS
59
non-Hodgkin's lymphoma
58
myelosuppression
57
epiphysis
55
cervical cancer
55
bone disease
54
more...
Symptom
pain
337
vomiting
42
dyspnea
31
starvation
29
nausea and vomiting
28
bone pain
28
nausea
27
distraction
27
headache
23
anesthesia
23
abdominal pain
22
weakness
21
seizures
21
collapse
19
diarrhea
18
chest pain
18
knee pain
15
analgesia
13
anorexia
13
thinning
13
cough
13
lethargy
12
cancer pain
12
back pain
11
fatigue
10
numbness
10
cachexia
9
low back pain
9
ataxia
8
flank pain
8
discomfort
8
discomfort
8
hoarseness
8
respiratory distress
7
exhaustion
7
syncope
7
hip pain
7
functional recovery
7
HSA
6
paresis
6
paresthesia
6
agitation
6
paraparesis
6
neck pain
5
shoulder pain
5
arthralgia
5
acidity
5
erythema
4
Ill
4
heel pain
4
sleepiness
4
Scratch
4
limb pain
4
dizziness
4
shortness of breath
4
leg pain
4
regurgitation
4
cyanosis
4
myalgia
4
hemoptysis
4
tingling
3
dysuria
3
sciatica
3
chills
3
ENT
3
thigh pain
3
abdominal discomfort
3
hypothermia
3
productive cough
3
tremor
3
abnormal gait
2
vertigo
2
acute pain
2
dysarthria
2
polydipsia
2
rhinorrhea
2
acute abdomen
2
intestinal bleeding
2
nipple discharge
2
spasm
2
more...
Drug
ROS
393
PTH
174
Adriamycin
111
Monit
62
lysine
59
Cardiovasc
43
ADM
38
caffeine
28
CSF
25
IL-2
24
Gel
22
Dermatol
21
CDP
20
CTX
20
GEO
19
ascorbate
19
IFN-gamma
17
ADR
15
ROC
14
Retinoic acid
14
G-CSF
13
Zoledronic acid
13
Taxol
12
MAP
12
ABC
11
IFN-beta
11
Arsenic trioxide
11
ICI
11
Forskolin
11
VCR
10
DNase I
10
Zoledronic acid
10
TiO2
10
BLM
10
Teriparatide
10
Denosumab
10
CAM
10
uPA
10
Indomethacin
9
Etoposide
9
VCR
9
NVP
8
Leucovorin
8
2-Methoxyestradiol
8
EE2
8
Mifamurtide
7
SiO2
7
vitamin E
7
NADH
7
Leaf
7
IL-11
7
G418
7
Gelatin
7
RFP
6
Growth hormone
6
CTX
6
CTX
6
Mutagen
6
Fluorescein
6
CoCl2
6
CoCl2
6
Growth hormone
6
ETS
6
ZnO
6
citric acid
5
Estrogens
5
Paraffin
5
Gleevec
4
CaCl2
4
Fluorescein
4
EHDP
4
Ethanol
4
Irinotecan
4
Vitamin A
4
CCL
4
Vindesine
4
Sorafenib
4
DEX
4
Auranofin
4
Doxycycline
4
more...
Enzyme
alkaline phosphatase
616
luciferase
460
mitogen-activated protein kinase
348
caspase-3
318
ERK
312
protein kinase
230
focal adhesion kinase
158
adenylate cyclase
136
PARP
118
protein kinase C
108
P-glycoprotein
93
caspase-9
84
reverse transcriptase
75
phospholipase C
73
MEK
70
caspase-8
65
collagenase
61
thymidine kinase
59
urokinase-type plasminogen activator
53
proteasome
52
ATPase
52
cdc2
51
lactate dehydrogenase
50
ACS
45
topoisomerase
41
phosphatidylinositol 3-kinase
41
GSK
38
AMPK
38
topoisomerase
38
MDP
37
RNA polymerase
37
dihydrofolate reductase
36
AMP-activated protein kinase
31
catalase
28
acid phosphatase
28
chloramphenicol acetyltransferase
28
glutathione S-transferase
26
peroxidase
26
phosphoinositide 3-kinase
24
matrix metalloproteinase 9
24
trypsin
23
MMP
23
AMPK
23
thrombin
20
complex I
19
superoxide dismutase
18
RNase
17
calcineurin
17
matrix metalloproteinase 2
17
IMP dehydrogenase
16
APC
16
RNase
16
thymidylate synthase
15
beta-galactosidase
15
MMP-3
15
endonuclease
15
alanine aminotransferase
14
glyceraldehyde-3-phosphate dehydrogenase
14
hyaluronidase
13
phosphodiesterase
13
neuraminidase
13
cathepsin K
13
transcriptase
13
CD10
12
IKK
12
ATP synthase
11
creatine kinase
11
DNA polymerase
11
plasmin
11
aldehyde dehydrogenase
10
glyceraldehyde-3-phosphate dehydrogenase
10
glyceraldehyde-3-phosphate dehydrogenase
10
aldehyde dehydrogenase
10
glyceraldehyde-3-phosphate dehydrogenase
10
aldehyde dehydrogenase
10
aldehyde dehydrogenase
10
aldehyde dehydrogenase
10
glyceraldehyde-3-phosphate dehydrogenase
10
lysozyme
10
hyaluronidase
10
more...
Compound
DNA
1350
Dec
1085
Clin
981
calcium
470
MTT
440
oxygen
288
phosphate
237
Adriamycin
175
cAMP
163
water
146
Methotrexate
144
sodium
143
vitamin D
129
ATP
118
bromide
115
DDP
113
tyrosine
113
acetate
102
MNNG
99
titanium
98
methionine
93
glucose
93
arginine
86
ADR
85
retinoic acid
83
iodine
82
MTX
82
sulfate
81
lysine
79
serine
71
TNF
67
cysteine
65
AMP
64
NH2
62
SDS
60
iron
60
zinc
60
nitrogen
58
ALP
55
His
55
MDA
53
hydrogen
51
PEG
50
leucine
47
MEK
47
threonine
47
ACS
45
ACS
45
Asp
43
galactose
43
ADP
40
salt
40
PEG
40
Insulin
40
alanine
39
TNM
39
silver
38
ADP
36
ADP
36
cobalt
35
PGE2
35
COS
35
GSH
34
proline
34
GSH
34
Gly
34
ethanol
33
creatinine
33
GTP
33
Phe
32
acridine
32
urea
30
phosphorus
30
nitric oxide
30
Vimentin
30
Dexamethasone
30
copper
30
25-dihydroxycholecalciferol
30
dUTP
29
N-acetylcysteine
29
more...