Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0029463 (
osteosarcoma
)
16,637
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
osteosarcoma
14617
Sep
1084
Mol
969
p53
755
alkaline phosphatase
614
HOS
447
osteogenic
440
rhabdomyosarcoma
418
caspase-3
393
ROS
393
collagen
376
osteocalcin
310
Bcl-2
240
AKT
233
parathyroid hormone
225
p21
206
catenin
197
PI3K
189
PTH
174
cytokine
172
pRb
171
vimentin
154
mTOR
144
matrix metalloproteinase
138
fibronectin
137
adenylate cyclase
134
vascular endothelial growth factor
134
MRI
123
endoplasmic reticulum
121
ERK
120
cyclin D1
118
ATP
118
UTR
115
insulin
114
p38
114
MAPK
113
ERK1
112
osteopontin
111
She
111
PARP
109
more...
Disease
osteosarcoma
16637
tumor
6675
cancer
5588
Osteosarcoma
2200
Osteosarcoma
2200
metastases
1656
sarcoma
1190
Ewing's sarcoma
830
chondrosarcoma
701
tumor growth
699
carcinoma
613
tumorigenesis
560
HOS
448
primary tumor
426
rhabdomyosarcoma
414
breast cancer
388
melanoma
385
fibrosarcoma
362
leukemia
340
tumor progression
337
bone cancer
327
lung metastases
316
retinoblastoma
307
neuroblastoma
290
lymphoma
260
metastatic osteosarcoma
258
adenocarcinoma
258
malignant fibrous histiocytoma
257
carcinogenesis
212
dysplasia
197
hepatocellular carcinoma
187
WT1
158
liposarcoma
156
leiomyosarcoma
154
Hodgkin's disease
148
lung cancer
147
squamous cell carcinoma
144
prostate cancer
143
osteoporosis
142
Sarcoma
138
more...
Symptom
pain
337
vomiting
42
dyspnea
31
starvation
29
bone pain
28
nausea and vomiting
28
nausea
27
distraction
27
anesthesia
23
headache
23
abdominal pain
22
seizures
21
weakness
21
collapse
19
chest pain
18
diarrhea
18
knee pain
15
cough
13
anorexia
13
analgesia
13
thinning
13
cancer pain
12
lethargy
12
back pain
11
fatigue
10
numbness
10
cachexia
9
low back pain
9
discomfort
8
hoarseness
8
flank pain
8
discomfort
8
ataxia
8
functional recovery
7
exhaustion
7
hip pain
7
syncope
7
respiratory distress
7
HSA
6
agitation
6
more...
Drug
ROS
393
PTH
174
Adriamycin
111
Monit
62
lysine
59
Cardiovasc
43
ADM
38
caffeine
28
CSF
25
IL-2
24
Gel
22
Dermatol
21
CDP
20
CTX
20
ascorbate
19
GEO
19
IFN-gamma
17
ADR
15
ROC
14
Retinoic acid
14
Zoledronic acid
13
G-CSF
13
MAP
12
Taxol
12
Arsenic trioxide
11
ICI
11
IFN-beta
11
Forskolin
11
ABC
11
VCR
10
DNase I
10
Zoledronic acid
10
TiO2
10
Teriparatide
10
Denosumab
10
BLM
10
CAM
10
uPA
10
Etoposide
9
VCR
9
more...
Enzyme
alkaline phosphatase
616
luciferase
460
mitogen-activated protein kinase
348
caspase-3
318
ERK
312
protein kinase
230
focal adhesion kinase
158
adenylate cyclase
136
PARP
118
protein kinase C
108
P-glycoprotein
93
caspase-9
84
reverse transcriptase
75
phospholipase C
73
MEK
70
caspase-8
65
collagenase
61
thymidine kinase
59
urokinase-type plasminogen activator
53
proteasome
52
ATPase
52
cdc2
51
lactate dehydrogenase
50
ACS
45
phosphatidylinositol 3-kinase
41
topoisomerase
41
topoisomerase
38
GSK
38
AMPK
38
RNA polymerase
37
MDP
37
dihydrofolate reductase
36
AMP-activated protein kinase
31
chloramphenicol acetyltransferase
28
catalase
28
acid phosphatase
28
peroxidase
26
glutathione S-transferase
26
matrix metalloproteinase 9
24
phosphoinositide 3-kinase
24
more...
Compound
DNA
1350
Dec
1085
Clin
981
calcium
470
MTT
440
oxygen
288
phosphate
237
Adriamycin
175
cAMP
163
water
146
Methotrexate
144
sodium
143
vitamin D
129
ATP
118
bromide
115
tyrosine
113
DDP
113
acetate
102
MNNG
99
titanium
98
methionine
93
glucose
93
arginine
86
ADR
85
retinoic acid
83
MTX
82
iodine
82
sulfate
81
lysine
79
serine
71
TNF
67
cysteine
65
AMP
64
NH2
62
SDS
60
iron
60
zinc
60
nitrogen
58
His
55
ALP
55
more...