Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029463 (osteosarcoma)
 16,637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

An outbred strain of Swiss mice carrying malignant neoplasms (48 female with mammary carcinoma, 1 male with osteosarcoma) is described with a high frequency of amyloid deposits selectively located in the ileum. Amyloid deposits were demonstrated by Congo red staining and electron microscopy. Comments are directed toward methods of amyloid detection, as well as pathogenic considerations.
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PMID:Spontaneous amyloidosis in mice with malignant neoplasms. 234 69

A 12-year-old male shih tzu dog was diagnosed as having a calcifying epithelial odontogenic tumour. One and a half years prior to presentation, a mass was noticed on the right mandible by the owners. Radiography revealed irregular, faintly radiopaque material within the tumour. A right hemimandibulectomy was performed, based on the clinical diagnosis of osteosarcoma. Histopathological evaluation of the mandibular mass showed that it was composed of a polyhedral odontogenic epithelial cell nest, fibrous stroma, homogeneous eosinophilic material and rounded calcifying material. The eosinophilic material was visualised by staining with Congo red, and observed under green birefringence by polarisation microscopy. Although the tumour had not recurred 12 months after surgery, the dog was euthanased because of aspiratic pharyngitis. The literature on the clinical behaviour of calcifying epithelial odontogenic tumours in dogs and cats is reviewed.
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PMID:Case of calcifying epithelial odontogenic tumour in a dog. 898 Dec 83