Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029463 (osteosarcoma)
 16,637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In the current study, we present a new and facile synthesis of N doped C-dots (N@C-dots) by hydrothermally reacting an aqueous solution of Bovine Serum Albumin (BSA). The as-prepared quantum dots (QDs) exhibited high quantum yield (44%), high photostability, colloidal stability, and high functionalization efficiency. In addition to their low cost, the N@C-dots have demonstrated a non-toxic and long-lasting effect when applied for imaging human cells (human osteosarcoma U2OS cells). Importantly, with high physiological stability, excellent biocompatibility, and homogenous distribution, the N@C-dot suspension was exploited for high quality cell imaging and to model the biological effects at the nuclear level. Moreover, the water-soluble N@C-dots are nontoxic to the selected cell line in our preliminary evaluation.
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PMID:A hydrothermal reaction of an aqueous solution of BSA yields highly fluorescent N doped C-dots used for imaging of live mammalian cells. 3226 69