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Query: UMLS:C0029463 (osteosarcoma)
 16,637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Parosteal osteosarcoma is a low-grade form of osteosarcoma that rarely affects the jaws. A case involving the maxilla of a 25-year-old man is presented, and four previously reported cases are reviewed.
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PMID:Parosteal osteosarcoma of the maxilla. 26 53

Juxtacortical osteosarcoma should be considered a very rate distinctive entity under all malignant bone tumors. The tumor has a remarkable tendency to grow from the periostal tissues peripherally with a usually marked degree of ossification without primary medullary involvement. It's different und characteristic behavior in clinical, roentgenographic and microscopic findings from that of other types of bone-forming sarkomas is discussed by means of a just treated case. In contrast to osteogenic osteosarcoma the prognosis for early well treated juxtacortical osteosarcoma is much better.
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PMID:[Juxtacortical osteosarcoma (author's transl)]. 106 68

Parosteal osteosarcoma is a low-grade malignant tumor arising from the periosteum. It involves mainly adults of third to sixth decades and the favorite site is the posterior aspect of distal femoral metaphysis. Microscopically, it is composed of woven to lamellar bone trabeculae within spindle cell stroma. We present a case of parosteal osteosarcoma that has very well-formed lamellar bone trabeculae and fat marrow under microscopic examination. Without the help of radiologic study, it is impossible to make the diagnosis of parosteal osteosarcoma.
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PMID:Parosteal osteosarcoma: a case report. 165 30

Parosteal osteogenic sarcoma is a distinct surface bone tumor with a better prognosis than conventional osteogenic sarcoma. We studied eight histologically proved cases of cranial parosteal osteogenic sarcoma. The tumors were identical in histologic appearance to parosteal osteosarcoma arising in long bones. Clinically, the tumor presented as a hard, painless, nodular scalp mass. The prevalence in women outnumbered that in men by 3:1, with most cases occurring between the second and third decades of life. Plain radiographs showed a rounded, sessile bone growth of variable size arising from the outer table of the skull. The tumor was heavily ossified centrally with variable margins and, at times, with radiating bony spicules at the periphery. No satellite bone nodules were noted in adjacent soft tissues. In three cases a fine radiolucent cleft was demonstrated between the tumor and the underlying outer table on the tangential radiographs or CT. After en bloc resection of the tumor, follow-ups for 20 years in one patient and 1 year in two patients showed no recurrence. Parosteal osteosarcoma of the skull is a rare low-grade tumor that usually arises from the outer table of the skull and has distinctive radiologic features that should distinguish it from other exophytic cranial bone neoplasms.
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PMID:Parosteal osteogenic sarcoma arising in cranial bones: clinical and radiologic features in eight patients. 211 31

Juxtacortical osteosarcomas, including periosteal and parosteal subtypes, are uncommon neoplasms of the jaws. In long bones, the biologic behavior of the periosteal variant is reported to be more aggressive than the parosteal tumor. Juxtacortical osteosarcoma of the jaws appears to have a slightly more favorable prognosis than in long bones, although a larger series of cases needs to be evaluated before a definitive conclusion concerning the behavior of juxtacortical osteosarcoma of the jaws can be made.
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PMID:Periosteal osteosarcoma of the maxilla: a case report and review of literature. 218 5

Parosteal osteosarcoma, a distinct entity in which the neoplasm arises on the bone surface, presents characteristic features. Thorough radiologic and histologic evaluation and early definitive surgery usually result in a favorable prognosis and make limb salvage feasible in many adult patients. Twenty-six patients with proven parosteal osteosarcoma were seen at The University of Texas M. D. Anderson Hospital and Tumor Institute at Houston. All were examined by conventional radiography, 16 by CT, and one by both CT and MR. CT is valuable for the evaluation of tumor invasion of the medullary canal, involvement of the cortex, and extension into the soft tissues, findings frequently not demonstrable by other noninvasive techniques. Additional information is obtained regarding the presence and location of satellite lesions and intralesional radiolucent areas and the relationship of the vascular bundle to the tumor mass. These findings are important for planning both percutaneous biopsy and surgery.
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PMID:Parosteal osteosarcoma: radiologic-pathologic correlation with emphasis on CT. 349 11

Parosteal osteosarcoma with either intralesional radiolucencies or extralesional clefts within the tumor was identified in eighteen patients. In each patient, both high-quality radiographs and whole macrosections of the lesions were available for correlative study of the radiolucencies. The intralesional radiolucencies were characterized as either deep or peripheral. Study of the macrosections showed that most of the peripheral lucent areas were comprised of low-grade malignant cartilaginous or fibrous tissue that was mixed with fat and bone trabeculae. The majority (67 per cent) of the high-grade dedifferentiated areas of tumor, however, corresponded to the deep radiolucencies. We think that the presence of a deep radiolucent area on a computed tomographic scan or other preoperative radiographic staging studies must create suspicion that a high-grade (grade-II) dedifferentiated region exists within an otherwise low-grade parosteal osteosarcoma.
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PMID:The meaning of radiolucencies in parosteal osteosarcoma. 386 May 5

Parosteal osteosarcoma is an uncommon malignant tumor of bone, and in a review of Mayo Clinic records we identified eleven cases of so-called dedifferentiated parosteal osteosarcoma. Ten of the eleven patients had had a long history of treatment for multiple recurrences of the tumor as a low-grade parosteal osteosarcoma and then for a definite recurrence as a high-grade undifferentiated osteosarcoma. The prognosis in this group of patients was similar to that in patients with conventional osteosarcoma.
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PMID:Dedifferentiated parosteal osteosarcoma. 658 Nov 70

Parosteal osteosarcoma carries the best prognosis of all forms of osteogenic sarcoma. In our series of cases, adequate resection of low- and moderate-grade lesions has resulted in long-term survival without any evidence of residual disease. Small lesions of less than 5 cm diameter and low grade cellular atypism are treatable by an en bloc resection with 2.5 cm margins of normal bone. Larger lesions, of Grade I-II malignancy, are more successfully treated by a two-stage resection spaced six months apart. Recurrences of low-grade tumors are also successfully treated by this method. Grade III lesions, and all those with intramedullary involvement, should be treated by measures appropriate for other types of high-grade osteogenic sarcoma. Special problems encountered in resection surgery are managed by prevention of pathologic fracture, bone grafts, avoidance or repair of major neurovascular structures, and preservation of joint function.
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PMID:Parosteal osteosarcoma: a treatment-oriented study. 693 63

A parosteal osteosarcoma of the distal femur with a typical radiographic and macroscopic appearance is reported. On histology the tumour was dominated by large numbers of osteoclast-like giant cells in a fibro-osseous background and islands of immature bone. Most of the neoplastic bone lacked osteoblastic rimming. There was no spatial relationship between the giant cells and areas of haemorrhage. Signs of 'dedifferentiation' were lacking. Cytogenetic a analysis revealed telomeric associations which are frequently found in giant cell tumours of bone. Parosteal osteosarcoma may, on histological appearances, hardly be recognizable as malignant. In addition, unusual changes such as abundant giant cells may be misleading in the absence of clinico-pathological correlation.
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PMID:Giant cell rich parosteal osteosarcoma. 755 6


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