Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0029463 (osteosarcoma)
16,637 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cardiac tumors are a rare disease. We show here one patient with a heart osteogenic sarcoma with chondroblastic differentiation. The clinical status was initiated with a cadre of cardiac tamponade. Transesophageal echocardiography and thoracic scanner were used to diagnose the cardiac tumor. The definitive diagnosis was confirmed with biopsy. At the present moment, there are very few cases reported in the references on osteogenic sarcoma with chondroblastic differentiation. The methods of diagnosis, the treatment and the histopathology are discussed.
...
PMID:[Cardiac osteogenic sarcoma with chondroblastic differentiation]. 868 76

A young patient with disseminated osteogenic sarcoma presented with cardiac tamponade. She was successfully managed with pericardiocentesis and intrapericardial instillation of cisplatin. There was no reaccumulation of pericardial fluid or recurrence of tamponade until the patient's death 12 months later. Intrapericardial chemotherapy may be effective in the management of cardiac tamponade secondary to malignancy.
...
PMID:Intrapericardial chemotherapy for the management of neoplastic cardiac tamponade. 1284 15

Congestive heart failure is a common presentation in small animal practice. Cardiac tumours are an unusual cause of congestive heart failure and, when they occur, usually cause clinical signs associated with pericardial effusion and cardiac tamponade. This case report outlines the clinical and histological findings in two dogs presented with clinical signs of congestive heart failure caused by obstruction of blood flow by intracavitary cardiac tumours. Case 1 showed signs of left-sided heart failure caused by osteosarcoma within the left atrial lumen, and case 2 presented with clinical signs of right-sided heart failure due to haemangiosarcoma occupying the right atrial and ventricular lumens. This case report provides further evidence for the inclusion of intracardiac neoplasia in the differential diagnosis for dogs with clinical signs of congestive heart failure.
...
PMID:Congestive heart failure caused by intracardiac tumours in two dogs. 1691 Nov 20