Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029089 (ophthalmoplegia)
3,338 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Correction of ptosis in patients with chronic progressive ophthalmoplegia is problematic because the ptosis enlarges the palpebral fissure and aggravates the lagophthalmos. Additional lifting of the lower lids, which are often retracted, therefore seems advisable. Experience with various lower lid elongation techniques is reported.
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PMID:[Lower eyelid extension-plasty in patients with ptosis in chronic progressive external ophthalmoplegia]. 188 64

Patients with chronic progressive external ophthalmoplegia (CPEO) are often disabled by ptosis; however, conventional ptosis surgery may induce lagophthalmos and exposure keratitis. Ten patients with CPEO underwent ptosis correction via bilateral frontalis suspensions, using monofilament synthetic material. Three of these patients were also treated with lower eyelid horizontal tightening. The frontalis sling was adjusted to provide a firm linkage between the eyebrow and eyelid, but was loose enough to allow eyelid closure when the frontalis muscle is relaxed. All patients experienced lessening of ptosis and relief from visual obstruction. One patient required reoperation of one eyelid for undercorrection. No lagophthalmos or corneal complications occurred. The rationale for treatment, preoperative evaluation, and operative procedure in CPEO is discussed herein.
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PMID:Management of ptosis in chronic progressive external ophthalmoplegia. 315 93

The surgical procedure using frontalis muscle and autogenous fascia lata suspension (Beard, Crawford) gives good results in the correction of severe blepharoptosis. Personal experience of 34 operations (23 patients) is reported. The level of the palpebral margin remains stable and there is no long-term undercorrection. The autogenous fascia lata is, in our experience, better than the other sling procedures. There is good tissular adhesion and less necrosis. The disadvantages are the constant lid lag in downward gaze and the scar on the thigh. The lagophthalmos is well tolerated and needs neither drops nor ointments 3 months post-operatively. Complications were infection (1 case) and corneal ulceration in a patient with traumatic ptosis and complete ophthalmoplegia. The sling must be deep and must support the suspensor ligament of Whitnall without perforating the conjunctiva. This step requires the use of a Reverdin needle, and is controlled by a finger applied in the superior fornix.
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PMID:[Treatment of severe ptosis by suspension of the upper eyelid using the autogenic frontal muscle and fascia lata. Analysis of 34 interventions]. 667 55

Four tarsorrhaphy sutures are placed through the lower eyelid and brow following ptosis surgery in a system designed for patients with external ophthalmoplegia, third nerve paralysis, and myashenia gravis. Three of the sutures connect the lower eyelid to the forehead, and the fourth suture is passed through the lower eyelid and taped to the cheek. The three lid-brow sutures are released during the first two postoperative weeks, one by one, and topical ointment instillations are gradually tapered. The tarsorrhaphy system allows the cornea to adapt gradually to the lagophthalmos that follows ptosis surgery. It also keeps the eyelids partially closed during the first two postoperative weeks in patients with frontalis sling surgery who have marked difficulty lowering their eyebrow and closing their eyelids because of early postoperative forehead edema and pain. The tarsorrhaphy system has prevented serious keratopathy in six patients with ptosis associated with abnormal ocular motility and in one patient with lagophthalmos following trauma. It also allowed the six ptosis patients to have full, rather than partial, correction of their ptosis.
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PMID:Suture tarsorrhaphy system to control keratopathy after ptosis surgery. 699 12