Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029089 (ophthalmoplegia)
 3,338 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report on the age and the causes of death in 16 patients with mitochondrial diseases. Nine patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) died at a mean age of 34 years and three patients with chronic progressive external ophthalmoplegia at a mean age of 56 years. The causes of death were cardiopulmonary failure (n = 5), status epilepticus (n = 4), aspiration pneumonia (n = 2), pulmonary embolism (n = 2), renal failure (n = 1), metabolic disturbance (n = 1), and unknown causes (n = 1). Thus, many patients in this series died of medical complications, some of which may be prevented.
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PMID:Age and cause of death in mitochondrial diseases. 1048 54

Ophthalmoplegia is an unusual finding in diffuse large B cell lymphoma. This report describes the case of a 72-year old male patient who presented with ophthalmoplegia but no gross neurological manifestations and an isolated mass in the left upper thigh. His ophthalmoplegia improved from his first cycle of systemic and intrathecal chemotherapy, his thigh mass effusion spontaneously resolved, and his laboratory tests also showed improvement. The patient remained well, though weak, for several months with no other neurological signs. He subsequently died from clinically diagnosed pulmonary embolism.
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PMID:Ophthalmoplegia with diffuse large B cell lymphoma: vital differential diagnosis. 1803 5