Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0029089 (ophthalmoplegia)
 3,338 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 57 year-old-man developed a left ophthalmoplegia associated with ataxia and areflexia while he had fever (39 degrees C) for two days. Dengue fever (DF) was diagnosed by definite criteria, i.e.: IgM seroconversion, positive culture from serum and positive PCR both from serum and CSF. Within one week, he fully and spontaneously recovered. To our knowledge, this neurological picture has never been reported in DF. Considering the immune-mediated nature of this condition, its pathogenesis in DF is proposed in reviewing the literature.
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PMID:[Probable Miller Fisher syndrome during Dengue fever type 2]. 1074 16

Dengue fever is endemic in the tropics and subtropics and has become a worldwide health threat in recent years. Dengue-related ocular complications are increasingly being reported from countries in South-East Asia. The authors report the first documented case of a patient with dengue fever who developed central retinal artery occlusion in addition to many other eye complications such as severe ptosis and complete internal and external ophthalmoplegia during her convalescent phase. The disease was confirmed by specific serological tests. Despite treatment, severe visual impairment occurred in this case.
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PMID:Central retinal artery occlusion secondary to dengue fever. 2535 30

A 14-year-old girl presented with encephalopathy, delirium and ophthalmoplegia following a 3day history of high-grade fever. Brain MRI on day 6 of illness showed diffusion restricted ovoid lesion in the splenium of corpus callosum. Dengue virus encephalitis was diagnosed with positive PCR for dengue virus type-2 in both serum and cerebrospinal fluid. She made a complete recovery from day 10 of illness. Repeat brain MRI on day 12 of illness showed resolution of the splenial lesion. Serial diffusion tensor imaging (DTI) showed normal fractional anisotropy values on resolution of splenial lesion indicating that MERS was likely due to transient interstitial oedema with preservation of white matter tracts. This is the first reported case of MERS following dengue virus infection. It highlights the usefulness of performing serial DTI in understanding the underlying pathogenesis of MERS. Our case report widens the neurological manifestations associated with dengue infection and reiterates that patients with MERS should be managed supportively as the splenial white matter tracts are reversibly involved in MERS.
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PMID:Mild encephalitis/encephalopathy with reversible splenial lesion (MERS) due to dengue virus. 2788 78