Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0028961 (oliguria)
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Human Gene/Protein
LDHL 11.3
TMOD1 10.9
aquaporin 7 9.8
DGKE 9.6
V4-6 9.0
RIFLE 8.6
SLC22A12 8.6
kidney injury molecule 1 8.5
OGC 8.3
HUS 8.3
V1-3 8.0
CFHR3 7.9
autosomal recessive) 7.9
COQ2 7.8
von Willebrand factor-cleaving protease 7.8
AGXT 7.7
urate transporter 1 7.6
RST 7.6
NAPA 7.6
amylase 1 7.4
CFHR1 7.4
SLC3A1 7.3
CEI 7.3
ARF 7.2
OSF 7.1
Complement C3 7.1
integrin alpha 3 7.1
E-like 7.0
GBM 6.9
B52 6.8
WAGR 6.8
L21 6.8
CPK 6.8
SAPS 6.7
uromodulin 6.5
tissue inhibitor of metalloproteinases-2 6.4
ABO blood type 6.4
RFI 6.3
phospholipase A2 receptor 6.3
ASK 6.3
neutrophil gelatinase-associated lipocalin 6.2
eosinophil major basic protein 6.2
FCE 6.1
Angiotensin II receptor 6.1
interleukin 18 6.0
Tamm-Horsfall glycoprotein 5.9
interleukin-18 5.9
mitofusin 2 5.8
NAG 5.8
TIL 5.8
A33 5.8
ECI 5.8
COL4A5 5.7
N-acetyl-beta-D-glucosaminidase 5.7
ADAMTS13 5.7
chronic renal failure 5.7
GFR 5.6
LAK 5.6
ABG 5.6
HTA 5.6
Alport syndrome 5.5
Lipocalin-2 5.5
beta-2-microglobulin 5.5
white cell 5.5
rohu 5.4
urinary kallikrein 5.4
SRI 5.4
myoglobin 5.4
carbamoylphosphate synthetase 5.4
GP1 5.4
muscle glycogen phosphorylase 5.3
CXCL16 5.3
ROMK 5.3
STH 5.3
PSP 5.3
ASAT 5.2
HRS 5.2
cysteine proteinase inhibitor 5.1
neurokinin 1 receptor 5.1
MTC 5.1
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Disease
Spontaneous rupture of bladder 14.1
Chronic urate nephropathy 14.1
Familial renal hypouricemia 13.5
Acute toxic nephropathy 13.1
Pigment nephropathy 13.1
Sopor 12.1
Renal hematuria 12.1
ATIN 12.1
Congenital sodium diarrhea 12.1
Episodic angioedema with eosinophilia 11.5
Kidney replacement 11.3
Ischemic enteritis 11.3
anuria 11.1
Post-infectious glomerulonephritis 11.1
Cardiac beriberi 11.1
Acute nephritis 10.9
Pulmonary renal syndrome 10.8
potassium intoxication 10.8
Listeria sepsis 10.8
Diarrhea-associated hemolytic uremic syndrome 10.6
Uremic syndrome 10.6
Renal cortical necrosis 10.6
Bilateral hydronephrosis 10.5
Irreversible shock 10.5
Acute renal insufficiency 10.3
Blackwater fever 10.3
Acute poststreptococcal glomerulonephritis 10.2
Nephropathia epidemica 10.1
Retinoic acid syndrome 10.1
Scleroderma renal crisis 10.0
azotemia 9.8
Capillary leak syndrome 9.8
Mesangioproliferative glomerulonephritis 9.8
Abdominal compartment syndrome 9.7
nervous breakdown 9.7
Acute interstitial nephritis 9.7
Nephrotic range proteinuria 9.6
Acute respiratory distress 9.6
Microangiopathic hemolytic anemia 9.5
Septic abortion 9.4
acute tubular necrosis 9.3
Ischemic hepatitis 9.3
acute renal failure 9.2
Azotemia 9.2
Adrenal hemorrhage 9.2
renal artery obstruction 9.1
acute glomerulonephritis 9.0
Klebsiella sepsis 8.9
tyrosinosis 8.9
Hemorrhagic fever with renal syndrome 8.9
Ovarian hyperstimulation syndrome 8.8
CPS deficiency 8.8
hemoglobinemia 8.8
Chronic pyelonephritis 8.8
Interrupted aortic arch 8.7
Parastomal hernia 8.6
fluid overload 8.6
Epstein syndrome 8.6
Aortocaval fistula 8.6
HIVAN 8.6
Severe pre-eclampsia 8.5
C1q nephropathy 8.4
Rapidly progressive glomerulonephritis 8.4
Acute mountain sickness 8.3
impaired judgment 8.3
adaptation reaction 8.2
glue sniffing 8.2
puerperal sepsis 8.2
Acute acalculous cholecystitis 8.2
Crush syndrome 8.1
Bloody diarrhea 8.1
tubular necrosis 8.1
Hantavirus pulmonary syndrome 8.1
hepatorenal syndrome 8.1
hemoglobinuria 8.0
Reversible posterior leukoencephalopathy syndrome 8.0
Twin-twin transfusion syndrome 7.9
Bladder outlet obstruction 7.9
interstitial nephritis 7.9
hemolytic uremic syndrome 7.9
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Symptom
oliguria 14.1
Vesical tenesmus 14.1
Left flank pain 11.8
lipuria 11.3
clammy skin 11.3
decreased skin turgor 10.9
Chills and fever 10.8
Mental status changes 9.8
carpopedal spasm 9.6
Multiple symptoms 9.3
Labor pain 9.1
vaginal itching 9.0
hyperosmia 8.9
dark urine 8.7
loin pain 8.3
polyuria 8.3
General symptoms 8.2
Murphy's sign 8.1
hypoproteinemia 7.2
generalized erythema 7.2
tachypnea 7.1
pallor 6.9
orthopnea 6.8
renal colic 6.7
flank pain 6.7
frequent urination 6.7
throat irritation 6.6
myalgia 6.4
giddiness 6.4
giddiness 6.4
chills 6.4
pedal edema 6.3
leg edema 6.3
abdominal cramps 6.0
rigors 6.0
non-productive cough 5.9
lassitude 5.9
abdominal discomfort 5.9
tense 5.8
polydipsia 5.8
rales 5.8
thirsty 5.7
vomiting 5.7
prostration 5.5
cyanosis 5.5
acute abdominal pain 5.4
abdominal pain 5.4
dysuria 5.4
consciousness disturbance 5.4
hemoptysis 5.3
hepatomegaly 5.3
sore throat 5.2
lethargy 5.2
tenesmus 5.2
nausea 5.2
hepatosplenomegaly 5.1
epigastric pain 5.1
lightheadedness 5.1
dyspnea 5.0
ataxic gait 5.0
urinary frequency 4.9
respiratory distress 4.9
excessive sweating 4.9
decreased appetite 4.9
anorexia 4.8
Sedation 4.7
back pain 4.7
right upper quadrant pain 4.7
Ill 4.6
hypothermia 4.5
chest tightness 4.5
photophobia 4.4
colic 4.4
diarrhea 4.4
intestinal bleeding 4.4
exertional dyspnea 4.3
nausea and vomiting 4.3
asthenia 4.3
arthralgia 4.3
muscle cramps 4.3
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Drug
Ibuprofen lysine 11.3
Zomepirac sodium 10.1
Dyazide 9.6
CDZM 9.1
Proleukin 9.0
Ergometrine 8.3
FMOX 8.1
Tiopronin 8.0
Torasemide 7.4
Hydergine 7.2
Levosimendan 6.8
Eculizumab 6.6
Tolvaptan 6.3
Entecavir 6.3
Entecavir 6.3
Magnesium sulfate 6.1
Diclofenac sodium 5.3
Nephron 5.2
MTC 5.1
Leucovorin 5.1
Piperacillin 5.1
Orphan 5.0
Simvastatin 5.0
Urokinase 4.8
Nephron 4.8
Ringer's solution 4.6
NAG 4.6
IPM 4.5
Prednisolone 4.5
TAC 4.4
Ceftazidime 4.4
Oxaliplatin 4.2
Prednisone 4.1
Propofol 4.0
AraC 4.0
Hypaque 4.0
Captopril 3.9
AMC 3.9
Hypaque 3.8
Vitamin B 3.8
Indomethacin 3.8
Fluconazole 3.7
Phenytoin 3.7
Rituximab 3.6
balanced salt solution 3.5
MgSO4 3.5
Coral 3.5
Triclosan 3.4
Albumin 3.4
Tacrolimus 3.4
CPR 3.4
Dial 3.3
uPA 3.0
Glycerol 2.9
Silica 2.8
IL-2 2.4
Vitamin E 2.4
Atropine 2.4
Kenyan 2.3
PCP 2.2
niacin 2.2
ampicillin 2.0
Adriamycin 1.9
Angiotensin II 1.8
CAM 1.6
MAP 1.1
ENT 1.0
nitroglycerin 1.0
CTX 0.8
Cardiovasc 0.7
Asn 0.6
caffeine -0.3
Leaf -0.3
IFN-gamma -0.7
lysine -0.8
Monit -1.0
Dermatol -1.9
Enzyme
AFR 8.4
SOR 5.6
N-acetylglucosaminyltransferase 5.1
creatine kinase 4.8
ADH 4.5
renin 4.5
AST 4.5
PRA 4.4
BAL 4.1
ACE 4.1
uricase 3.8
alanine aminotransferase 3.8
aspartate aminotransferase 3.8
thromboplastin 3.4
aldolase 3.3
lactate dehydrogenase 3.2
prostaglandin synthetase 3.2
kallikrein 3.1
hypoxanthine-guanine phosphoribosyltransferase 2.8
xanthine oxidase 2.6
alcohol dehydrogenase 2.5
isocitrate dehydrogenase 2.5
5'-nucleotidase 2.4
isocitrate dehydrogenase 2.3
prostate-specific antigen 2.3
arginase 2.2
PCP 2.2
calcineurin 2.0
PAH 2.0
plasmin 1.9
hyaluronidase 1.9
lipase 1.9
CPR 1.7
urokinase-type plasminogen activator 1.7
hyaluronidase 1.5
beta-lactamase 1.4
urease 1.2
MAP 1.2
urease 1.2
thymidine kinase 1.2
peroxidase 1.1
thrombin 1.1
alkaline phosphatase 0.8
CD10 0.8
monoamine oxidase 0.7
ATPase 0.1
catalase -0.1
phosphodiesterase -0.1
lysozyme -0.3
acetylcholinesterase -0.7
proteasome -0.7
superoxide dismutase -0.8
RNA polymerase -1.0
trypsin -1.3
Compound
4-amino-2-chlorophenol 13.1
Dimethylaminopropionitrile 12.5
3-Chloroaniline 12.1
Enalkiren 11.8
2-amino-4-chlorophenol 10.4
2-amino-4-chlorophenol 10.4
1-hydrazinophthalazine 9.2
Infecundin 9.0
2,3-dimercapto-1-propanol 8.2
2,3-dimercapto-1-propanol 8.2
CBr4 8.2
Tolazoline 8.1
Tienilic acid 8.0
Hippuran 7.7
A 99 7.7
PTO 7.6
Stanozolol 7.5
Stanozolol 7.4
Stanozolol 7.3
Potassium chloride 7.3
creatinine 7.1
Meglumine 7.1
9H-xanthen-9-one 7.1
Ergonovine 6.9
PIH 6.7
Oxazepam 6.7
Barbiturate 6.5
Diazoxide 6.2
ASK 6.1
Ergot 6.1
Mannitol 6.0
ANCA 6.0
Mannitol 6.0
Cefoperazone 6.0
Magnesium sulfate 6.0
Miconazole 5.9
Letrozole 5.9
Magnesium sulfate 5.8
Probenecid 5.8
Milrinone 5.8
Fenofibrate 5.8
urea 5.8
Melamine 5.8
Meperidine 5.7
Azathioprine 5.7
Cefazolin 5.7
Remifentanil 5.6
Interleukin-2 5.6
Salix 5.6
Patulin 5.6
Pyridoxine 5.5
Inulin 5.5
N-acetylmannosamine 5.5
6-Mercaptopurine 5.4
2,3-dimercaptosuccinic acid 5.4
Cystine 5.3
Ibuprofen 5.3
Nitrendipine 5.3
MAOA 5.2
2-chlorophenol 5.2
Cortisone 5.2
2-chlorophenol 5.2
SDA 5.1
PSP 5.1
Piperacillin 5.1
Levetiracetam 5.1
Paroxetine 5.1
MTC 5.1
DIC 5.0
Sudan I 5.0
Quinine 5.0
PVP-I 5.0
Triiodothyronine 5.0
LPR 5.0
Thiobarbituric acid 4.9
Polymyxin B 4.9
carbonic acid 4.8
carbonic acid 4.8
carbonic acid 4.8
carbonic acid 4.8
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