Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028961 (oliguria)
 1,847 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The changes in serum and urinary levels of calcium and phosphorus and serum parathyroid hormone (PTH) were studied during controlled, chemically induced, acute renal disease in 4 ponies. There was an initial rise in daily urinary calcium and hydroxyproline excretion in 2 ponies which may have indicated increased bone resorption. Mild hypercalcemia, hypophosphatemia and elevated C-terminal PTH levels were associated with oliguria. Total daily urinary excretion of calcium and phosphorus decreased as oliguria developed. The levels of C-terminal PTH were increased in all four animals. This appears to have been related to their diminished renal function in that C-terminal fragments of intact PTH (which require functioning kidneys in order to be cleared) were probably being accumulated. Although there was no evidence with regard to an actual increase in PTH secretion, prolongation of intact PTH half-life due to renal tubular damage may have contributed to the development of hypercalcemia.
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PMID:Alterations in calcium, phosphorus and C-terminal parathyroid hormone levels in equine acute renal disease. 373 86

In patients with haemorrhagic fever with renal syndrome (HFRS) and in those who had HFRS in the past ionized calcium (Ca2+) and parathyroid hormone (PTH) levels were measured in the blood. High levels of PTH in normal or low those of Ca2+ were typical for HFRS oliguria. Hyperparathyroidism observed was assessed as an adaptation reaction preventing oliguria-related Ca2+ fall. In cured patients neither Ca2+ nor PTH deviation were reported.
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PMID:[The level of ionized calcium in the blood and parathyroid function in acute kidney failure in patients with hemorrhagic fever with renal syndrome]. 790 80