Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028961 (oliguria)
 1,847 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The author observed 477 patients with sub- and decompensated stenosis of the pylorus of ulcer etiology; 11 out of them developed a severe complication--chloroprivic tetany which resulted from repeated abundant vomiting in emaciated patients and was followed by an acute total dehydration of the body, decrease of chlorides, oliguria and azotemia. Some problems concerning the prevention and the treatment of this severe complication of peptic ulcer are described.
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PMID:[Clinical aspects and therapy of gastrogenic tetany]. 71 43

Dehydration is a common presentation to any emergency department with symptoms ranging from lethargy, confusion, oliguria as well as those specific to the underlying cause. In this case we describe a young patient who following a short history of vomiting and abdominal pain developed carpopedal spasm and distal parasthesia on a background of Gitelman syndrome. Biochemical blood analysis showed a marked hypokalaemia, hypomagnesaemia and mild metabolic alkalosis in addition to a prolonged QTc interval of 592 ms seen on ECG. Following fluid replacement and electrolyte correction his clinical symptoms resolved along with QTc normalisation. This case demonstrates a patient with a rare and interesting renal disorder who presented with typical biochemical and ECG abnormalities in addition to tetany in the presence of normal plasma calcium.
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PMID:Localised normocalcaemic tetany secondary to dehydration in an individual with Gitelman syndrome. 2363 12