Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0028961 (oliguria)
1,847 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Diuresis was found to diminish considerably in dogs with removed (by enucleation or burning out) parathyroid glands chiefly on account of intensified tubular reabsorption. In the mechanism of oliguria in hypoparathyroidism a definite role is played by hypocalciemia. An acute reduction of blood calcium in intact dogs also suppressed diuresis. Dogs with hypoparathyroidism displayed a marked elevation of blood plasma antidiuretic activity and a high level of reabsorption of osmotically free water. Intravenous injection of adrenoblocker dihydroergotamine eliminated the suppression of diuresis in the parathyroprived dogs. Apparently, a definite role in the origin of oliguria belonged to substances of adrenergic nature.
...
PMID:[Mechanism of oliguria in experimental hypoparathyroidism]. 68 77

A case of 7-year-old boy with tetralogy of Fallot associated with DiGeorge syndrome was reported. He had been diagnosed as cardio-facial syndrome with hypoparathyroidism because of hypocalcemia, convulsion, cardiac defect and the characteristic face. But immunologic study showed hypofunction of cellular immunity and cardiac catheterization and angiogram revealed the Tetralogy of Fallot. So we diagnosed as DiGeorge syndrome and performed operation. The thymus was not found and we close the ventricular defect with patch and reconstructed right ventricular outflow tract with transannular patch. We often measured serum ionized calcium level and corrected with calcium gluconate intravenously. Peritoneal dialysis was done due to oliguria and much inotropic support was necessary.
...
PMID:[Cardiac surgery of tetralogy of Fallot associated with DiGeorge syndrome: a case report]. 260 81