Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0028754 (
obesity
)
124,988
document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
0.029
leptin
0.023
adiponectin
0.010
adipokine
0.005
Leptin
0.004
resistin
0.003
leptin receptor
0.003
uncoupling protein 1
0.003
Adiponectin
0.002
HDL
0.002
ghrelin
0.002
gut
0.001
peroxisome proliferator-activated receptor
0.001
FTO
0.001
melanocortin-4 receptor
0.001
MC4R
0.001
peroxisome proliferator-activated receptor gamma
0.001
AMP-activated protein kinase
0.001
uncoupling protein
0.001
aP2
0.001
epididymal
0.001
visfatin
0.001
agouti
0.001
fatty acid synthase
0.001
glucagon
0.001
IRS-1
0.001
C-reactive protein
0.001
AMPK
0.001
insulin receptor
0.001
Fibroblast growth factor 21
0.001
Resistin
0.001
PPAR
0.000
UCP2
0.000
fat mass and obesity associated
0.000
melanocortin 4 receptor
0.000
peptide YY
0.000
neuropeptide Y
0.000
chemerin
0.000
perilipin
0.000
adipose triglyceride lipase
0.000
NIDDM
0.000
Ghrelin
0.000
hormone-sensitive lipase
0.000
lipoprotein lipase
0.000
TMEM18
0.000
proopiomelanocortin
0.000
PRDM16
0.000
Protein tyrosine phosphatase 1B
0.000
GLP-1
0.000
pancreatic lipase
0.000
GLP-1 receptor
0.000
vaspin
0.000
UCP3
0.000
GLUT4
0.000
HSD1
0.000
SREBP-1c
0.000
PGC
0.000
glucose-dependent insulinotropic polypeptide
0.000
IL-6
0.000
plasminogen activator inhibitor-1
0.000
Mol
0.000
TNF
0.000
acetyl-CoA carboxylase
0.000
GNPDA2
0.000
SEC16B
0.000
tumor necrosis factor
0.000
NEGR1
0.000
sex hormone-binding globulin
0.000
LEPR
0.000
sterol regulatory element-binding protein
0.000
SH2B1
0.000
Sep
0.000
CD36
0.000
ALMS1
0.000
cytokine
0.000
KCTD15
0.000
BBS1
0.000
tubby
0.000
interleukin-6
0.000
stearoyl-CoA desaturase
0.000
more...
Disease
obesity
1.000
metabolic syndrome
0.033
type 2 diabetes
0.025
diabetes
0.022
dyslipidemia
0.012
hypertension
0.011
cardiovascular disease
0.008
fatty liver
0.008
glucose intolerance
0.008
hyperinsulinemia
0.007
hyperphagia
0.006
abdominal obesity
0.006
hyperlipidemia
0.004
morbid obesity
0.004
Nonalcoholic fatty liver
0.003
Overweight and obesity
0.003
hyperglycemia
0.003
alcoholic fatty liver
0.003
overnutrition
0.003
polycystic ovary syndrome
0.002
atherosclerosis
0.002
obstructive sleep apnea
0.001
gestational diabetes mellitus
0.001
coronary heart disease
0.001
hypercholesterolemia
0.001
sleep apnea
0.001
Bardet-Biedl syndrome
0.001
chronic disease
0.001
hyperandrogenism
0.001
moderate obesity
0.001
prediabetes
0.001
hypogonadism
0.001
binge eating
0.001
metabolic disorder
0.001
malnutrition
0.000
cancer
0.000
hyperuricemia
0.000
coronary artery disease
0.000
acanthosis nigricans
0.000
liver disease
0.000
heart disease
0.000
anovulation
0.000
syndrome X
0.000
cirrhosis
0.000
bulimia nervosa
0.000
cardiovascular risk factor
0.000
Cushing's syndrome
0.000
depression
0.000
endometrial cancer
0.000
heart failure
0.000
osteoporosis
0.000
chronic liver disease
0.000
eating disorder
0.000
stroke
0.000
renal disease
0.000
Obesity hypoventilation syndrome
0.000
lipodystrophy
0.000
endocrine disorder
0.000
Hypothalamic obesity
0.000
osteoarthritis
0.000
atherosclerotic cardiovascular disease
0.000
infertility
0.000
nutritional disorder
0.000
metabolic syndrome X
0.000
myocardial infarction
0.000
asthma
0.000
essential hypertension
0.000
vitamin D deficiency
0.000
anorexia nervosa
0.000
gastroesophageal reflux disease
0.000
breast cancer
0.000
fetal macrosomia
0.000
Brown
0.000
type 1 diabetes
0.000
microalbuminuria
0.000
gallstones
0.000
BBS6
0.000
Laurence-Moon-Biedl syndrome
0.000
preeclampsia
0.000
vascular disease
0.000
more...
Symptom
overweight
0.061
hunger
0.001
snoring
0.000
cachexia
0.000
anorexia
0.000
hypotonia
0.000
sleepiness
0.000
corpulence
0.000
starvation
0.000
fatigue
0.000
weight problem
0.000
stigma
0.000
pain
0.000
Cushingoid
0.000
angina
0.000
insomnia
0.000
Cushingoid
0.000
hypercapnia
0.000
anesthesia
0.000
constipation
0.000
dyspnea
0.000
polyuria
0.000
Decreased activity
0.000
headache
0.000
hypersomnia
0.000
polydipsia
0.000
hepatomegaly
0.000
room spinning
0.000
eds
0.000
weakness
0.000
discomfort
0.000
High weight
0.000
respiratory distress
0.000
knee pain
0.000
discomfort
0.000
vomiting
0.000
back pain
0.000
Postprandial pain
0.000
Fear symptoms
0.000
ketonuria
0.000
Multimorbidity
0.000
physical appearance
0.000
nausea
0.000
heartburn
0.000
exhaustion
0.000
Frontal headache
0.000
diarrhea
0.000
absent menses
0.000
Appetite suppression
0.000
emaciation
0.000
Depressive symptoms
0.000
menopausal symptoms
0.000
low back pain
0.000
seizures
0.000
abnormal breathing
0.000
masculinization
0.000
arthralgia
0.000
collapse
0.000
Poor sleep
0.000
hypothermia
0.000
abdominal pain
0.000
acid regurgitation
0.000
decreased appetite
0.000
Chronic hypoventilation
0.000
wheezing
0.000
enuresis
0.000
unable to taste
0.000
bitter taste
0.000
hot flashes
0.000
reproductive problem
0.000
Tissue sensitivity
0.000
Male sexual dysfunction
0.000
analgesia
0.000
cough
0.000
acute stress
0.000
CSR
0.000
Mixed incontinence
0.000
exertional dyspnea
0.000
Catch
0.000
male subfertility
0.000
more...
Drug
Orlistat
0.001
Rimonabant
0.000
Liraglutide
0.000
Glucagon
0.000
Meridia
0.000
Meridia
0.000
Dexfenfluramine
0.000
Fructose
0.000
Rosiglitazone
0.000
Diethylpropion
0.000
Bifidobacterium
0.000
Cardiovasc
0.000
vitamin E
0.000
niacin
0.000
Growth hormone
0.000
Growth hormone
0.000
Mazindol
0.000
ADM
0.000
ROS
0.000
caffeine
0.000
ascorbate
0.000
Asthma
0.000
Exenatide
0.000
APD-356
0.000
Monosodium glutamate
0.000
Cassia seed
0.000
Axokine
0.000
Eucommia bark
0.000
Phendimetrazine tartrate
0.000
Trodusquemine
0.000
GHRP
0.000
EPA
0.000
Troglitazone
0.000
Kaempherol
0.000
Leaf
0.000
Aicar
0.000
Diethylpropion hydrochloride
0.000
Calcifediol
0.000
Estrogens
0.000
Avandia
0.000
Vitamin A
0.000
Dirlotapide
0.000
ROC
0.000
Verofylline
0.000
Glyceraldehyde-3-Phosphate
0.000
Asperlin
0.000
Liposyn
0.000
Metreleptin
0.000
1-Deoxynojirimycin
0.000
Kenyan
0.000
lysine
0.000
Ciclazindol
0.000
Ezetimibe
0.000
Rosuvastatin
0.000
Hakka
0.000
Caraway oil
0.000
Sergliflozin
0.000
Schisandra fruit
0.000
Meteneprost
0.000
Fenfluramine hydrochloride
0.000
Ertiprotafib
0.000
Pramlintide
0.000
Colestimide
0.000
MAP
0.000
Olive oil
0.000
Dermatol
0.000
Redux
0.000
Coix seed
0.000
Citrus unshiu peel
0.000
Angiotensin II
0.000
Lard
0.000
Ciglitazone
0.000
Peptavlon
0.000
Permax
0.000
Permax
0.000
Acino
0.000
Monit
0.000
PTH
0.000
Carbenoxolone
0.000
Polydextrose
0.000
more...
Enzyme
AMP-activated protein kinase
0.001
AMPK
0.001
hormone-sensitive lipase
0.000
lipoprotein lipase
0.000
AMPK
0.000
acetyl-CoA carboxylase
0.000
renin
0.000
lipase
0.000
alanine aminotransferase
0.000
mitogen-activated protein kinase
0.000
11beta-hydroxysteroid dehydrogenase
0.000
BAT
0.000
diacylglycerol acyltransferase
0.000
CPT
0.000
LPL
0.000
protein kinase
0.000
aspartate aminotransferase
0.000
AMP-activated kinase
0.000
phosphoenolpyruvate carboxykinase
0.000
glycerol-3-phosphate dehydrogenase
0.000
glycerol-3-phosphate dehydrogenase
0.000
ACE
0.000
proprotein convertase 1
0.000
glucokinase
0.000
ketohexokinase
0.000
ERK
0.000
acyl-CoA oxidase
0.000
AST
0.000
phosphatidylinositol 3-kinase
0.000
phosphoenolpyruvate carboxykinase
0.000
superoxide dismutase
0.000
carboxypeptidase E
0.000
phosphoenolpyruvate carboxykinase
0.000
monoacylglycerol acyltransferase
0.000
glucose-6-phosphatase
0.000
citrate synthase
0.000
nicotinamide phosphoribosyltransferase
0.000
focal adhesion kinase
0.000
NADPH oxidase
0.000
PDK1
0.000
CYP7A1
0.000
CPT
0.000
NADPH oxidase
0.000
AOR
0.000
CPT
0.000
IKK
0.000
gamma-glutamyl transpeptidase
0.000
paraoxonase
0.000
fatty-acid synthase
0.000
HSD
0.000
catalase
0.000
alpha-glucosidase
0.000
demethylase
0.000
glutathione peroxidase
0.000
phosphoinositide 3-kinase
0.000
caspase-1
0.000
hypotaurine dehydrogenase
0.000
flavonol-3-O-glucoside L-rhamnosyltransferase
0.000
luciferase
0.000
MGAT
0.000
phosphatidylethanolamine N-methyltransferase
0.000
bile salt hydrolase
0.000
monoacylglycerol lipase
0.000
protein kinase C
0.000
acyl-CoA synthetase
0.000
tissue plasminogen activator
0.000
pyruvate dehydrogenase
0.000
pyruvate dehydrogenase
0.000
pyruvate dehydrogenase
0.000
NO synthase
0.000
angiotensin-converting enzyme 2
0.000
acetate CoA-transferase
0.000
paraoxonase
0.000
lysophospholipase D
0.000
acyl-CoA dehydrogenase
0.000
phosphodiesterase
0.000
nicotinamide N-methyltransferase
0.000
calpain 5
0.000
GSK
0.000
acyl-CoA synthetase
0.000
more...
Compound
glucose
0.009
silver
0.004
Insulin
0.002
Sibutramine
0.001
Pima
0.000
Clin
0.000
Dec
0.000
TNF
0.000
Oil Red O
0.000
Oil Red O
0.000
vitamin D
0.000
Metformin
0.000
Metformin
0.000
oxygen
0.000
palmitic acid
0.000
Cholesterol
0.000
Phentermine
0.000
FFA
0.000
palmitic acid
0.000
aldosterone
0.000
Glucagon
0.000
creatinine
0.000
glycerol
0.000
calcium
0.000
Pac
0.000
DHA
0.000
water
0.000
Cardiol
0.000
Diethylpropion
0.000
DNA
0.000
DBP
0.000
CoA
0.000
Diabetol
0.000
sodium
0.000
DBP
0.000
Fenfluramine
0.000
nitric oxide
0.000
Fructose
0.000
Diabetol
0.000
Conjugated linoleic acid
0.000
salt
0.000
ATP
0.000
Vitamin D
0.000
Resveratrol
0.000
homocysteine
0.000
Testosterone
0.000
Testosterone
0.000
DPP
0.000
ACTH
0.000
Pioglitazone
0.000
Guggulsterone
0.000
Bisphenol A
0.000
Bisphenol A
0.000
retinol
0.000
cAMP
0.000
tyrosine
0.000
MSG
0.000
5-HT
0.000
Sucrose
0.000
malonyl-CoA
0.000
potassium
0.000
FMI
0.000
Fucoxanthin
0.000
arginine
0.000
iron
0.000
Acyl-CoA
0.000
AMP
0.000
nicotinamide
0.000
PMA
0.000
serine
0.000
caffeine
0.000
ethanol
0.000
DHA
0.000
glutamate
0.000
Celastrol
0.000
celastrol
0.000
NAD
0.000
DHA
0.000
CPT
0.000
alpha-MSH
0.000
more...