Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0028754 (
obesity
)
124,988
document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
27897
leptin
7858
Sep
7384
Mol
4374
gut
3642
adiponectin
3611
HDL
2358
cytokine
1945
Leptin
1712
adipokine
1424
glucagon
1417
IL-6
1352
TNF
1339
C-reactive protein
1291
tumor necrosis factor
1281
peroxisome proliferator-activated receptor
1199
ghrelin
1134
epididymal
1016
leptin receptor
993
uncoupling protein 1
914
endoplasmic reticulum
906
AMP-activated protein kinase
892
resistin
883
peroxisome proliferator-activated receptor gamma
880
renin
870
ATP
834
growth hormone
817
Adiponectin
803
insulin receptor
799
hemoglobin
771
interleukin-6
766
neuropeptide Y
689
AMPK
644
mTOR
615
beta-endorphin
611
fatty acid synthase
587
IRS-1
584
lipoprotein lipase
544
lipopolysaccharide
528
PPAR
523
collagen
497
albumin
477
lipase
474
ACTH
472
plasminogen activator inhibitor-1
439
uncoupling protein
419
FTO
396
fibrinogen
394
MAPK
388
AKT
382
Men
374
GLUT4
371
insulin-like growth factor
368
PI3K
368
alanine aminotransferase
365
cholecystokinin
365
MRI
365
TLR4
364
agouti
362
PGC
356
CRP
355
Pol
354
visfatin
353
angiotensin II
353
IL-10
350
STAT3
348
superoxide dismutase
343
Ghrelin
341
GLP-1 receptor
340
TNF-alpha
339
NIDDM
335
histone
329
proopiomelanocortin
322
CD36
320
GLP-1
320
hormone-sensitive lipase
319
peptide YY
319
aP2
319
ANOVA
317
glucose transporter
317
more...
Disease
obesity
124988
diabetes
27445
hypertension
15328
type 2 diabetes
13374
metabolic syndrome
10003
cardiovascular disease
8296
cancer
7966
dyslipidemia
4625
atherosclerosis
3967
fatty liver
3794
glucose intolerance
3462
hyperglycemia
3131
hyperinsulinemia
3076
hyperlipidemia
2714
depression
2352
hyperphagia
2195
stroke
2064
tumor
2037
coronary heart disease
1835
breast cancer
1765
heart failure
1483
coronary artery disease
1459
hypercholesterolemia
1457
abdominal obesity
1430
chronic disease
1425
polycystic ovary syndrome
1415
obstructive sleep apnea
1370
asthma
1358
malnutrition
1304
cirrhosis
1266
heart disease
1208
myocardial infarction
1201
Nonalcoholic fatty liver
1191
morbid obesity
1175
liver disease
1172
renal disease
1122
alcoholic fatty liver
1080
osteoporosis
1076
gestational diabetes mellitus
1025
hepatocellular carcinoma
1015
sleep apnea
1005
Alzheimer's disease
933
osteoarthritis
916
cold
834
infertility
773
myocardial ischemia
689
carcinogenesis
659
colorectal cancer
659
type 1 diabetes
623
hypogonadism
615
endometrial cancer
589
overnutrition
589
metabolic disorder
575
essential hypertension
562
arthritis
552
hypoglycemia
533
infectious diseases
527
cognitive impairment
523
vascular disease
518
schizophrenia
516
chronic liver disease
515
Overweight and obesity
514
dementia
490
Brown
484
preeclampsia
480
gastroesophageal reflux disease
479
binge eating
477
prostate cancer
476
chronic obstructive pulmonary disease
472
hyperandrogenism
467
proteinuria
451
adenocarcinoma
447
inflammatory bowel disease
440
rheumatoid arthritis
440
addiction
437
HIV
432
hyperuricemia
428
ischemia
422
gallstones
422
anemia
420
more...
Symptom
overweight
14147
pain
1229
hunger
923
fatigue
613
anesthesia
551
starvation
439
anorexia
430
sleepiness
368
headache
303
cachexia
297
stigma
289
snoring
287
hypotonia
279
angina
272
seizures
232
dyspnea
221
weakness
213
diarrhea
213
insomnia
190
vomiting
180
discomfort
166
hypercapnia
153
discomfort
151
nausea
145
respiratory distress
143
constipation
142
abdominal pain
135
collapse
133
back pain
110
analgesia
108
exhaustion
104
hypothermia
101
cough
99
hepatomegaly
87
low back pain
82
chest pain
74
polyuria
72
arthralgia
67
polydipsia
56
knee pain
53
wheezing
50
dizziness
46
ataxia
44
tremor
43
acute stress
43
heartburn
42
masculinization
40
hypersomnia
40
Ill
39
nausea and vomiting
37
physical appearance
37
regurgitation
37
Depressive symptoms
37
lethargy
36
eds
36
exertional dyspnea
35
menopausal symptoms
33
distraction
33
functional recovery
31
memory loss
30
Decreased activity
29
syncope
29
Cushingoid
28
enuresis
28
shortness of breath
28
thinning
28
emaciation
27
corpulence
27
paresis
26
Cushingoid
26
decreased appetite
25
bitter taste
25
agitation
25
Wind
24
paresthesia
23
splenomegaly
22
asthenia
22
alexithymia
22
ketonuria
22
dystonia
21
more...
Drug
Cardiovasc
921
Dermatol
356
vitamin E
254
Asthma
241
caffeine
231
ascorbate
229
ROS
223
Orlistat
221
Glucagon
200
lysine
194
Bifidobacterium
164
Leaf
147
Rimonabant
132
Monit
122
niacin
116
Dial
109
Fructose
108
Growth hormone
101
Growth hormone
97
ADM
95
EPA
91
MAP
87
ROC
82
Liraglutide
75
Rosiglitazone
69
NADH
66
IL-2
63
Nephron
62
CSF
60
Spectrum
56
EE2
55
Vitamin A
53
PTH
53
Kenyan
48
Angiotensin II
48
Estrogens
46
lactose
43
citric acid
39
nitroglycerin
38
Portal
37
CTX
33
Vitamin E
32
ENT
31
IFN-gamma
29
CTX
29
Spectrum
29
CTX
29
ABC
29
Histamine
28
Dexfenfluramine
28
Glycerol
27
ALA
26
GHRP
26
Exenatide
26
Asn
26
Posture
26
Troglitazone
24
Albumin
24
Ginseng
23
CAM
23
Nephron
23
Retinoic acid
22
Award
22
Glutathione
21
Ethanol
21
p75
21
Glycyrrhiza
20
Check
20
Heme
19
IL-1ra
19
Nitric Oxide
19
Gel
18
Mazindol
18
CCL
18
THF
17
Android
17
Ezetimibe
16
Diurnal
16
Rosuvastatin
16
Alliance
16
more...
Enzyme
AMP-activated protein kinase
1475
mitogen-activated protein kinase
1243
renin
870
protein kinase
834
alanine aminotransferase
667
AMPK
659
AMPK
644
ERK
564
lipase
557
lipoprotein lipase
556
superoxide dismutase
411
aspartate aminotransferase
386
focal adhesion kinase
324
hormone-sensitive lipase
316
acetyl-CoA carboxylase
301
catalase
297
ACE
277
protein kinase C
229
CPT
223
luciferase
222
ATPase
185
phosphatidylinositol 3-kinase
181
glutathione peroxidase
179
alkaline phosphatase
168
NADPH oxidase
159
phosphoenolpyruvate carboxykinase
153
NADPH oxidase
145
11beta-hydroxysteroid dehydrogenase
139
AST
137
gamma-glutamyl transpeptidase
129
caspase-3
127
phosphodiesterase
125
LPL
121
NO synthase
121
peroxidase
116
citrate synthase
110
phosphoenolpyruvate carboxykinase
110
phosphoenolpyruvate carboxykinase
109
proteasome
109
BAT
108
tissue plasminogen activator
107
ACS
107
glucokinase
105
lactate dehydrogenase
100
diacylglycerol acyltransferase
99
MEK
97
IKK
96
calcineurin
94
glycerol-3-phosphate dehydrogenase
93
demethylase
92
thrombin
92
caspase-1
92
glycerol-3-phosphate dehydrogenase
92
glucose-6-phosphatase
91
phosphoinositide 3-kinase
90
APC
86
CPT
83
CPT
83
alpha-glucosidase
81
reverse transcriptase
79
tyrosine hydroxylase
79
collagenase
76
phospholipase A2
75
HSD
74
pyruvate dehydrogenase
74
acetylcholinesterase
73
complex I
72
GSK
72
PDK1
70
adenylate cyclase
66
glutathione S-transferase
62
creatine kinase
62
cholinesterase
59
xanthine oxidase
59
AOR
59
pyruvate dehydrogenase
57
pyruvate dehydrogenase
57
acyl-CoA oxidase
56
MAP
55
paraoxonase
52
more...
Compound
glucose
18416
Clin
9042
Dec
8283
silver
5517
Insulin
2830
oxygen
2615
DNA
2373
water
2244
calcium
1637
TNF
1339
sodium
1323
Cardiol
1288
vitamin D
855
ATP
834
salt
775
nitric oxide
766
creatinine
736
iron
617
ethanol
584
glycerol
581
tyrosine
562
aldosterone
536
potassium
517
arginine
514
phosphate
510
Pac
498
acetate
461
cAMP
436
glutamate
415
zinc
411
serine
409
palmitic acid
398
Cholesterol
376
AMP
331
nitrogen
329
CoA
316
5-HT
306
palmitic acid
296
ACTH
294
alanine
283
Metformin
276
sulfate
275
leucine
274
Metformin
274
hydrogen
264
lysine
260
noradrenaline
259
Diabetol
258
CO2
257
urea
251
His
248
methionine
248
NAD
243
galactose
236
homocysteine
232
caffeine
231
Pima
224
DHA
220
Diabetol
218
nicotinamide
206
Glucagon
200
NAD
200
Oil Red O
197
threonine
197
GSH
195
GSH
195
retinol
192
tryptophan
189
Oil Red O
186
cysteine
184
Vitamin D
182
PMA
177
tryptophan
173
FFA
171
tryptophan
166
tryptophan
166
Testosterone
165
Testosterone
165
DBP
163
TSH
161
more...