Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0028754 (obesity)
124,988 document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 27897
leptin 7858
Sep 7384
Mol 4374
gut 3642
adiponectin 3611
HDL 2358
cytokine 1945
Leptin 1712
adipokine 1424
glucagon 1417
IL-6 1352
TNF 1339
C-reactive protein 1291
tumor necrosis factor 1281
peroxisome proliferator-activated receptor 1199
ghrelin 1134
epididymal 1016
leptin receptor 993
uncoupling protein 1 914
endoplasmic reticulum 906
AMP-activated protein kinase 892
resistin 883
peroxisome proliferator-activated receptor gamma 880
renin 870
ATP 834
growth hormone 817
Adiponectin 803
insulin receptor 799
hemoglobin 771
interleukin-6 766
neuropeptide Y 689
AMPK 644
mTOR 615
beta-endorphin 611
fatty acid synthase 587
IRS-1 584
lipoprotein lipase 544
lipopolysaccharide 528
PPAR 523
collagen 497
albumin 477
lipase 474
ACTH 472
plasminogen activator inhibitor-1 439
uncoupling protein 419
FTO 396
fibrinogen 394
MAPK 388
AKT 382
Men 374
GLUT4 371
insulin-like growth factor 368
PI3K 368
alanine aminotransferase 365
cholecystokinin 365
MRI 365
TLR4 364
agouti 362
PGC 356
CRP 355
Pol 354
visfatin 353
angiotensin II 353
IL-10 350
STAT3 348
superoxide dismutase 343
Ghrelin 341
GLP-1 receptor 340
TNF-alpha 339
NIDDM 335
histone 329
proopiomelanocortin 322
CD36 320
GLP-1 320
hormone-sensitive lipase 319
peptide YY 319
aP2 319
ANOVA 317
glucose transporter 317
more...
Disease
obesity 124988
diabetes 27445
hypertension 15328
type 2 diabetes 13374
metabolic syndrome 10003
cardiovascular disease 8296
cancer 7966
dyslipidemia 4625
atherosclerosis 3967
fatty liver 3794
glucose intolerance 3462
hyperglycemia 3131
hyperinsulinemia 3076
hyperlipidemia 2714
depression 2352
hyperphagia 2195
stroke 2064
tumor 2037
coronary heart disease 1835
breast cancer 1765
heart failure 1483
coronary artery disease 1459
hypercholesterolemia 1457
abdominal obesity 1430
chronic disease 1425
polycystic ovary syndrome 1415
obstructive sleep apnea 1370
asthma 1358
malnutrition 1304
cirrhosis 1266
heart disease 1208
myocardial infarction 1201
Nonalcoholic fatty liver 1191
morbid obesity 1175
liver disease 1172
renal disease 1122
alcoholic fatty liver 1080
osteoporosis 1076
gestational diabetes mellitus 1025
hepatocellular carcinoma 1015
sleep apnea 1005
Alzheimer's disease 933
osteoarthritis 916
cold 834
infertility 773
myocardial ischemia 689
carcinogenesis 659
colorectal cancer 659
type 1 diabetes 623
hypogonadism 615
endometrial cancer 589
overnutrition 589
metabolic disorder 575
essential hypertension 562
arthritis 552
hypoglycemia 533
infectious diseases 527
cognitive impairment 523
vascular disease 518
schizophrenia 516
chronic liver disease 515
Overweight and obesity 514
dementia 490
Brown 484
preeclampsia 480
gastroesophageal reflux disease 479
binge eating 477
prostate cancer 476
chronic obstructive pulmonary disease 472
hyperandrogenism 467
proteinuria 451
adenocarcinoma 447
inflammatory bowel disease 440
rheumatoid arthritis 440
addiction 437
HIV 432
hyperuricemia 428
ischemia 422
gallstones 422
anemia 420
more...
Symptom
overweight 14147
pain 1229
hunger 923
fatigue 613
anesthesia 551
starvation 439
anorexia 430
sleepiness 368
headache 303
cachexia 297
stigma 289
snoring 287
hypotonia 279
angina 272
seizures 232
dyspnea 221
weakness 213
diarrhea 213
insomnia 190
vomiting 180
discomfort 166
hypercapnia 153
discomfort 151
nausea 145
respiratory distress 143
constipation 142
abdominal pain 135
collapse 133
back pain 110
analgesia 108
exhaustion 104
hypothermia 101
cough 99
hepatomegaly 87
low back pain 82
chest pain 74
polyuria 72
arthralgia 67
polydipsia 56
knee pain 53
wheezing 50
dizziness 46
ataxia 44
tremor 43
acute stress 43
heartburn 42
masculinization 40
hypersomnia 40
Ill 39
nausea and vomiting 37
physical appearance 37
regurgitation 37
Depressive symptoms 37
lethargy 36
eds 36
exertional dyspnea 35
menopausal symptoms 33
distraction 33
functional recovery 31
memory loss 30
Decreased activity 29
syncope 29
Cushingoid 28
enuresis 28
shortness of breath 28
thinning 28
emaciation 27
corpulence 27
paresis 26
Cushingoid 26
decreased appetite 25
bitter taste 25
agitation 25
Wind 24
paresthesia 23
splenomegaly 22
asthenia 22
alexithymia 22
ketonuria 22
dystonia 21
more...
Drug
Cardiovasc 921
Dermatol 356
vitamin E 254
Asthma 241
caffeine 231
ascorbate 229
ROS 223
Orlistat 221
Glucagon 200
lysine 194
Bifidobacterium 164
Leaf 147
Rimonabant 132
Monit 122
niacin 116
Dial 109
Fructose 108
Growth hormone 101
Growth hormone 97
ADM 95
EPA 91
MAP 87
ROC 82
Liraglutide 75
Rosiglitazone 69
NADH 66
IL-2 63
Nephron 62
CSF 60
Spectrum 56
EE2 55
Vitamin A 53
PTH 53
Kenyan 48
Angiotensin II 48
Estrogens 46
lactose 43
citric acid 39
nitroglycerin 38
Portal 37
CTX 33
Vitamin E 32
ENT 31
IFN-gamma 29
CTX 29
Spectrum 29
CTX 29
ABC 29
Histamine 28
Dexfenfluramine 28
Glycerol 27
ALA 26
GHRP 26
Exenatide 26
Asn 26
Posture 26
Troglitazone 24
Albumin 24
Ginseng 23
CAM 23
Nephron 23
Retinoic acid 22
Award 22
Glutathione 21
Ethanol 21
p75 21
Glycyrrhiza 20
Check 20
Heme 19
IL-1ra 19
Nitric Oxide 19
Gel 18
Mazindol 18
CCL 18
THF 17
Android 17
Ezetimibe 16
Diurnal 16
Rosuvastatin 16
Alliance 16
more...
Enzyme
AMP-activated protein kinase 1475
mitogen-activated protein kinase 1243
renin 870
protein kinase 834
alanine aminotransferase 667
AMPK 659
AMPK 644
ERK 564
lipase 557
lipoprotein lipase 556
superoxide dismutase 411
aspartate aminotransferase 386
focal adhesion kinase 324
hormone-sensitive lipase 316
acetyl-CoA carboxylase 301
catalase 297
ACE 277
protein kinase C 229
CPT 223
luciferase 222
ATPase 185
phosphatidylinositol 3-kinase 181
glutathione peroxidase 179
alkaline phosphatase 168
NADPH oxidase 159
phosphoenolpyruvate carboxykinase 153
NADPH oxidase 145
11beta-hydroxysteroid dehydrogenase 139
AST 137
gamma-glutamyl transpeptidase 129
caspase-3 127
phosphodiesterase 125
LPL 121
NO synthase 121
peroxidase 116
citrate synthase 110
phosphoenolpyruvate carboxykinase 110
phosphoenolpyruvate carboxykinase 109
proteasome 109
BAT 108
tissue plasminogen activator 107
ACS 107
glucokinase 105
lactate dehydrogenase 100
diacylglycerol acyltransferase 99
MEK 97
IKK 96
calcineurin 94
glycerol-3-phosphate dehydrogenase 93
demethylase 92
thrombin 92
caspase-1 92
glycerol-3-phosphate dehydrogenase 92
glucose-6-phosphatase 91
phosphoinositide 3-kinase 90
APC 86
CPT 83
CPT 83
alpha-glucosidase 81
reverse transcriptase 79
tyrosine hydroxylase 79
collagenase 76
phospholipase A2 75
HSD 74
pyruvate dehydrogenase 74
acetylcholinesterase 73
complex I 72
GSK 72
PDK1 70
adenylate cyclase 66
glutathione S-transferase 62
creatine kinase 62
cholinesterase 59
xanthine oxidase 59
AOR 59
pyruvate dehydrogenase 57
pyruvate dehydrogenase 57
acyl-CoA oxidase 56
MAP 55
paraoxonase 52
more...
Compound
glucose 18416
Clin 9042
Dec 8283
silver 5517
Insulin 2830
oxygen 2615
DNA 2373
water 2244
calcium 1637
TNF 1339
sodium 1323
Cardiol 1288
vitamin D 855
ATP 834
salt 775
nitric oxide 766
creatinine 736
iron 617
ethanol 584
glycerol 581
tyrosine 562
aldosterone 536
potassium 517
arginine 514
phosphate 510
Pac 498
acetate 461
cAMP 436
glutamate 415
zinc 411
serine 409
palmitic acid 398
Cholesterol 376
AMP 331
nitrogen 329
CoA 316
5-HT 306
palmitic acid 296
ACTH 294
alanine 283
Metformin 276
sulfate 275
leucine 274
Metformin 274
hydrogen 264
lysine 260
noradrenaline 259
Diabetol 258
CO2 257
urea 251
His 248
methionine 248
NAD 243
galactose 236
homocysteine 232
caffeine 231
Pima 224
DHA 220
Diabetol 218
nicotinamide 206
Glucagon 200
NAD 200
Oil Red O 197
threonine 197
GSH 195
GSH 195
retinol 192
tryptophan 189
Oil Red O 186
cysteine 184
Vitamin D 182
PMA 177
tryptophan 173
FFA 171
tryptophan 166
tryptophan 166
Testosterone 165
Testosterone 165
DBP 163
TSH 161
more...