Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0028754 (
obesity
)
124,988
document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
insulin
27897
leptin
7858
Sep
7384
Mol
4374
gut
3642
adiponectin
3611
HDL
2358
cytokine
1945
Leptin
1712
adipokine
1424
glucagon
1417
IL-6
1352
TNF
1339
C-reactive protein
1291
tumor necrosis factor
1281
peroxisome proliferator-activated receptor
1199
ghrelin
1134
epididymal
1016
leptin receptor
993
uncoupling protein 1
914
endoplasmic reticulum
906
AMP-activated protein kinase
892
resistin
883
peroxisome proliferator-activated receptor gamma
880
renin
870
ATP
834
growth hormone
817
Adiponectin
803
insulin receptor
799
hemoglobin
771
interleukin-6
766
neuropeptide Y
689
AMPK
644
mTOR
615
beta-endorphin
611
fatty acid synthase
587
IRS-1
584
lipoprotein lipase
544
lipopolysaccharide
528
PPAR
523
more...
Disease
obesity
124988
diabetes
27445
hypertension
15328
type 2 diabetes
13374
metabolic syndrome
10003
cardiovascular disease
8296
cancer
7966
dyslipidemia
4625
atherosclerosis
3967
fatty liver
3794
glucose intolerance
3462
hyperglycemia
3131
hyperinsulinemia
3076
hyperlipidemia
2714
depression
2352
hyperphagia
2195
stroke
2064
tumor
2037
coronary heart disease
1835
breast cancer
1765
heart failure
1483
coronary artery disease
1459
hypercholesterolemia
1457
abdominal obesity
1430
chronic disease
1425
polycystic ovary syndrome
1415
obstructive sleep apnea
1370
asthma
1358
malnutrition
1304
cirrhosis
1266
heart disease
1208
myocardial infarction
1201
Nonalcoholic fatty liver
1191
morbid obesity
1175
liver disease
1172
renal disease
1122
alcoholic fatty liver
1080
osteoporosis
1076
gestational diabetes mellitus
1025
hepatocellular carcinoma
1015
more...
Symptom
overweight
14147
pain
1229
hunger
923
fatigue
613
anesthesia
551
starvation
439
anorexia
430
sleepiness
368
headache
303
cachexia
297
stigma
289
snoring
287
hypotonia
279
angina
272
seizures
232
dyspnea
221
diarrhea
213
weakness
213
insomnia
190
vomiting
180
discomfort
166
hypercapnia
153
discomfort
151
nausea
145
respiratory distress
143
constipation
142
abdominal pain
135
collapse
133
back pain
110
analgesia
108
exhaustion
104
hypothermia
101
cough
99
hepatomegaly
87
low back pain
82
chest pain
74
polyuria
72
arthralgia
67
polydipsia
56
knee pain
53
more...
Drug
Cardiovasc
921
Dermatol
356
vitamin E
254
Asthma
241
caffeine
231
ascorbate
229
ROS
223
Orlistat
221
Glucagon
200
lysine
194
Bifidobacterium
164
Leaf
147
Rimonabant
132
Monit
122
niacin
116
Dial
109
Fructose
108
Growth hormone
101
Growth hormone
97
ADM
95
EPA
91
MAP
87
ROC
82
Liraglutide
75
Rosiglitazone
69
NADH
66
IL-2
63
Nephron
62
CSF
60
Spectrum
56
EE2
55
PTH
53
Vitamin A
53
Kenyan
48
Angiotensin II
48
Estrogens
46
lactose
43
citric acid
39
nitroglycerin
38
Portal
37
more...
Enzyme
AMP-activated protein kinase
1475
mitogen-activated protein kinase
1243
renin
870
protein kinase
834
alanine aminotransferase
667
AMPK
659
AMPK
644
ERK
564
lipase
557
lipoprotein lipase
556
superoxide dismutase
411
aspartate aminotransferase
386
focal adhesion kinase
324
hormone-sensitive lipase
316
acetyl-CoA carboxylase
301
catalase
297
ACE
277
protein kinase C
229
CPT
223
luciferase
222
ATPase
185
phosphatidylinositol 3-kinase
181
glutathione peroxidase
179
alkaline phosphatase
168
NADPH oxidase
159
phosphoenolpyruvate carboxykinase
153
NADPH oxidase
145
11beta-hydroxysteroid dehydrogenase
139
AST
137
gamma-glutamyl transpeptidase
129
caspase-3
127
phosphodiesterase
125
LPL
121
NO synthase
121
peroxidase
116
phosphoenolpyruvate carboxykinase
110
citrate synthase
110
proteasome
109
phosphoenolpyruvate carboxykinase
109
BAT
108
more...
Compound
glucose
18416
Clin
9042
Dec
8283
silver
5517
Insulin
2830
oxygen
2615
DNA
2373
water
2244
calcium
1637
TNF
1339
sodium
1323
Cardiol
1288
vitamin D
855
ATP
834
salt
775
nitric oxide
766
creatinine
736
iron
617
ethanol
584
glycerol
581
tyrosine
562
aldosterone
536
potassium
517
arginine
514
phosphate
510
Pac
498
acetate
461
cAMP
436
glutamate
415
zinc
411
serine
409
palmitic acid
398
Cholesterol
376
AMP
331
nitrogen
329
CoA
316
5-HT
306
palmitic acid
296
ACTH
294
alanine
283
more...