Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0028754 (obesity)
124,988 document(s) hit in 31,850,051 MEDLINE articles (0.06 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
insulin 27897
leptin 7858
Sep 7384
Mol 4374
gut 3642
adiponectin 3611
HDL 2358
cytokine 1945
Leptin 1712
adipokine 1424
glucagon 1417
IL-6 1352
TNF 1339
C-reactive protein 1291
tumor necrosis factor 1281
peroxisome proliferator-activated receptor 1199
ghrelin 1134
epididymal 1016
leptin receptor 993
uncoupling protein 1 914
endoplasmic reticulum 906
AMP-activated protein kinase 892
resistin 883
peroxisome proliferator-activated receptor gamma 880
renin 870
ATP 834
growth hormone 817
Adiponectin 803
insulin receptor 799
hemoglobin 771
interleukin-6 766
neuropeptide Y 689
AMPK 644
mTOR 615
beta-endorphin 611
fatty acid synthase 587
IRS-1 584
lipoprotein lipase 544
lipopolysaccharide 528
PPAR 523
more...
Disease
obesity 124988
diabetes 27445
hypertension 15328
type 2 diabetes 13374
metabolic syndrome 10003
cardiovascular disease 8296
cancer 7966
dyslipidemia 4625
atherosclerosis 3967
fatty liver 3794
glucose intolerance 3462
hyperglycemia 3131
hyperinsulinemia 3076
hyperlipidemia 2714
depression 2352
hyperphagia 2195
stroke 2064
tumor 2037
coronary heart disease 1835
breast cancer 1765
heart failure 1483
coronary artery disease 1459
hypercholesterolemia 1457
abdominal obesity 1430
chronic disease 1425
polycystic ovary syndrome 1415
obstructive sleep apnea 1370
asthma 1358
malnutrition 1304
cirrhosis 1266
heart disease 1208
myocardial infarction 1201
Nonalcoholic fatty liver 1191
morbid obesity 1175
liver disease 1172
renal disease 1122
alcoholic fatty liver 1080
osteoporosis 1076
gestational diabetes mellitus 1025
hepatocellular carcinoma 1015
more...
Symptom
overweight 14147
pain 1229
hunger 923
fatigue 613
anesthesia 551
starvation 439
anorexia 430
sleepiness 368
headache 303
cachexia 297
stigma 289
snoring 287
hypotonia 279
angina 272
seizures 232
dyspnea 221
diarrhea 213
weakness 213
insomnia 190
vomiting 180
discomfort 166
hypercapnia 153
discomfort 151
nausea 145
respiratory distress 143
constipation 142
abdominal pain 135
collapse 133
back pain 110
analgesia 108
exhaustion 104
hypothermia 101
cough 99
hepatomegaly 87
low back pain 82
chest pain 74
polyuria 72
arthralgia 67
polydipsia 56
knee pain 53
more...
Drug
Cardiovasc 921
Dermatol 356
vitamin E 254
Asthma 241
caffeine 231
ascorbate 229
ROS 223
Orlistat 221
Glucagon 200
lysine 194
Bifidobacterium 164
Leaf 147
Rimonabant 132
Monit 122
niacin 116
Dial 109
Fructose 108
Growth hormone 101
Growth hormone 97
ADM 95
EPA 91
MAP 87
ROC 82
Liraglutide 75
Rosiglitazone 69
NADH 66
IL-2 63
Nephron 62
CSF 60
Spectrum 56
EE2 55
PTH 53
Vitamin A 53
Kenyan 48
Angiotensin II 48
Estrogens 46
lactose 43
citric acid 39
nitroglycerin 38
Portal 37
more...
Enzyme
AMP-activated protein kinase 1475
mitogen-activated protein kinase 1243
renin 870
protein kinase 834
alanine aminotransferase 667
AMPK 659
AMPK 644
ERK 564
lipase 557
lipoprotein lipase 556
superoxide dismutase 411
aspartate aminotransferase 386
focal adhesion kinase 324
hormone-sensitive lipase 316
acetyl-CoA carboxylase 301
catalase 297
ACE 277
protein kinase C 229
CPT 223
luciferase 222
ATPase 185
phosphatidylinositol 3-kinase 181
glutathione peroxidase 179
alkaline phosphatase 168
NADPH oxidase 159
phosphoenolpyruvate carboxykinase 153
NADPH oxidase 145
11beta-hydroxysteroid dehydrogenase 139
AST 137
gamma-glutamyl transpeptidase 129
caspase-3 127
phosphodiesterase 125
LPL 121
NO synthase 121
peroxidase 116
phosphoenolpyruvate carboxykinase 110
citrate synthase 110
proteasome 109
phosphoenolpyruvate carboxykinase 109
BAT 108
more...
Compound
glucose 18416
Clin 9042
Dec 8283
silver 5517
Insulin 2830
oxygen 2615
DNA 2373
water 2244
calcium 1637
TNF 1339
sodium 1323
Cardiol 1288
vitamin D 855
ATP 834
salt 775
nitric oxide 766
creatinine 736
iron 617
ethanol 584
glycerol 581
tyrosine 562
aldosterone 536
potassium 517
arginine 514
phosphate 510
Pac 498
acetate 461
cAMP 436
glutamate 415
zinc 411
serine 409
palmitic acid 398
Cholesterol 376
AMP 331
nitrogen 329
CoA 316
5-HT 306
palmitic acid 296
ACTH 294
alanine 283
more...