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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In obesity resistant to traditional low calory diets, the authors alternated short periods of moderate low calory intake (600 to 1,000 calories) with periods of very restrictive low calory intake (230 to 300 calories). The results of this method are analysed in 105 patients. This method permits loss of weight in difficult cases of obesity, both during intensely low calory diets and during less severe low calory diets. This technique is well accepted by the patients and is less monotonous than very unbalanced multi-fractionated diets or with prolonged courses of fasting. The results are all the more satisfactory when the patient is young, when the obesity is recent and marked, which does not, however, exclude its efficacy in long-standing cases of obesity.
Sem Hop 1976 Nov 23
PMID:[Alternating low calory diets (200 to 1000 calories), their value in the treatment of resistant obesity]. 18 76

Insulin resistance may occur to a variable degree in various disease conditions. Obesity is frequently accompanied by insulin resistance. The anti-insulin antibodies in patients treated with insulin are a classical cause, but in fact rare. Insulin resistance of variable degree may accompany certain metabolic disorders, e.g. diabetic ketosis and acidosis, and endocrine disorders, e.g. Cushing's syndrome, acromegaly. The measurement of insulin receptors brings a new dimension to the investigation of insulin resistance. Insulin receptors are reduced in number during obesity. The abnormality, partly responsible for insulin resistance, is reducible by reduction in calory intake. Circulating insulin anti-receptor antibodies appear to be responsible for insulin resistance which is particularly marked although exeptional, in nonobese diabetics with acanthosis nigrans and auto-immune symptoms.
Sem Hop 1977 Jun 23
PMID:[New data in the domain of insulin resistance]. 19 31

In a school population of 532 boys between 10 and 18 years and 287 girls between 10 and 15 years, were drawn up the normal weight height ratios and blood pressures. The frequency of obesity was 6% in both sexes. Girls were more obese than boys. The disease started before the age of 5--6 years. They are frequently familial. A narrow correlation exists between the weight height ratios and blood pressure. The obese patients had in 8 cases a high systolic blood pressure and in 4 cases a high diastolic blood pressure. Half the hypertensive patients were over weight. A strong link between obesity and high blood pressure was also found in the family history. These facts should lead us to treat obesity in children by slimming diets or at least prevent the disease by an appropriate diet. Half the cases of high blood pressure in children and adolescents improved on losing weight.
Sem Hop 1978 Jun
PMID:[Obesity, hypertension and their relationship in children and adolescents. An epidemiological study in schools (author's transl)]. 21 12

The psycho-motor sedative action of tiapride, which has been demonstrated in internal medicine, was studied in anesthesiology. A group of 253 patients hospitalized for urological (203 cases) or gynaecological (50 cases) operations were given standard premedication together with 100 to 300 mg of tiapride. Preoperative sedation and reduction of anxiety was excellent in 138 cases, moderate in 97 cases, and nil in 18 cases, under the influence of tiapride. Tiapride was perfectly well tolerated even in patients with debility, obesity, alcoholism and cardiac or respiratory insufficiency.
Sem Hop 1978 Jun
PMID:[Tiapride in anesthesiology]. 21 21

Distributions and correlations of serum uric acid (SUA) were studied in 13,885 men and 6,861 women who were between the ages of 20 and 90. In men and women the distribution of SUA is unimodal. The average SUA value is 6,28 mg/100 ml SD: 1,19) in men and 5,05 mg/100 ml (SD: 1,10) in women, 27% of the men and 4% of the women have a SUA level above 7 mg/100 ml. In men and in women correlations of SUA with an obesity index is strong (r = 0,272; r = 0,311). In men partial correlations between SUA and age, blood pressure, cholesterolemia, glycemia and hemoglobinemia diminish when obesity index is fixed. In women these correlations are stronger and do not vary when obesity index is fixed. In men and women the correlation between SUA and creatininemia is strong and do not vary when obesity index is fixed.
Sem Hop
PMID:[Distribution and correlations of serum uric-acid in two French adult populations: 13,885 men and 6,861 women (author's transl)]. 21 33

The authors report three observations of patients having suffered from arthralgias as an aftermath of intestinal by-pass for treatment of refractory obesity. They remind the main troubles cropping up after such surgical treatment and refer to the data already existing in the literature dealing with articular manifestations. They think this pathology is in keeping with arthritis already reported in inflammatory colitis and they suggest a similar pathogeny.
Sem Hop
PMID:[Iatrogenic arthritis after intestinal by-pass as a treatment for obesity (author's transl)]. 624 54

In 273 patients divided in 12 classes according to the weight, plasma T3, T4 and TSH, thyroid response to TSH and pituitary response to TRF are the same in each category. There is no reason of value for giving thyroid extract in the treatment of obesity.
Sem Hop
PMID:[Is thyroid extract necessary in the treatment of obesity? (author's transl)]. 625 8

Menopausal disorders coincide with the onset of luteal insufficiency and the resulting relative hyperestrogenism. At this stage the risks to be assessed are mainly related to a worsening of the menstrual syndrome (heaviness of the legs, abdominal distention, water retention, mastodynia, depressive syndrome), cycle changes, or various genital types of hemorrhage requiring investigation for detection of a possible fibroma, hyperplasia, endometriosis, or genital cancer. Once the menopause is settled a reduction in estrogen levels comes with reactive increases in FSM and LM levels, and the principal risk is the development of a cancer. The role of endogenous (obesity, diabetes, Stein-Leventhal, adenomatous hyperplasia) or exogenous (prolonged estrogen therapy alone) estrogens has to be evaluated in endometrial cancer. Cancer of the vulva also appears to be more frequent in menopausal women (natural or artificial), as well as cervical cancer and cancer of the breast. There is an apparent increase in cardiovascular risks in untreated menopausal women, but this is still discussed, as to the benefits of estrogen therapy.
Sem Hop
PMID:[Menopausal risk factors (author's transl)]. 625 25

Short and long term weight loss was studied in 173 obese patients treated by a low-calorie diet. Significant weight loss was observed in 78% of the patients after 6 months and in 58% after 4 years. These results are similar to those published in other studies but the comparison is difficult because the methods used are not strictly comparable. A detailed study of 116 patients showed that weight loss is not significantly influenced by such variables as age, sex, previous calorie intake, complications, and severity or duration of the obesity.
Sem Hop 1982 Apr 15
PMID:[Short and long term results in the treatment of obesity. A study in 173 patients (author's transl)]. 628 13

Obese patients who fasted during seven days were divided into four groups according to whether they received triiodothyronine (100 to 150 microgram per day), calcitonin (1 MRC unit per day), both T3 and calcitonin, or neither of these two hormones. Urinary calcium and phosphate were increased in patients receiving T3 or calcitonin. T3 given with calcitonin did not increase the calcitonin-induced calciuria but did increase the phosphaturia. The authors suggest a possible explanation for these findings. No changes in serum parathormone were recorded during fasting acidosis.
Sem Hop 1982 Jun 10
PMID:[Urinary calcium and phosphate during fasting. Effect of various hormonal factors (author's transl)]. 628 6


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