Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)


Obesity (Silver Spring) 2006 Feb
PMID:Age-dependent changes in body size of Greek boys from 1982 to 2002. 1657 55


Obesity (Silver Spring) 2006 Feb
PMID:Dietary linolenic acid and fasting glucose and insulin: the National Heart, Lung, and Blood Institute Family Heart Study. 1657 56


Obesity (Silver Spring) 2006 Feb
PMID:Racial and ethnic differences in secular trends for childhood BMI, weight, and height. 1657 57


Obesity (Silver Spring) 2006 Feb
PMID:Serum amyloid A: a marker of adiposity-induced low-grade inflammation but not of metabolic status. 1657 58


Obesity (Silver Spring) 2006 Feb
PMID:Adiponectin, visceral fat, oxidative stress, and early macrovascular disease: the Coronary Artery Risk Development in Young Adults Study. 1657 59


Obesity (Silver Spring) 2006 Feb
PMID:Associations among education, cortisol rhythm, and BMI in blue-collar women. 1657 60


Obesity (Silver Spring) 2006 Feb
PMID:Visceral fat is an independent predictor of all-cause mortality in men. 1657 61


Obesity (Silver Spring) 2006 Feb
PMID:Central nervous system regulation of food intake. 1664 56

The obesity epidemic has focused attention on the endocrine function of adipose tissue. Adipose tissue secretes leptin, cytokines, complement factors, and components of the coagulation cascade, most of which are increased in obesity. In contrast, a strong negative correlation exists between adiponectin and adiposity, insulin sensitivity, diabetes, vascular inflammation, and atherosclerosis. Adiponectin treatment in rodents increases insulin sensitivity and reduces lipids and atherogenesis. Chronic and central adiponectin treatment reduces weight, glucose, and lipids. The insulin-sensitizing action of thiazolidinediones is mediated, in part, through adiponectin. A causal role of adiponectin in diabetes, dyslipidemia, and atherosclerosis has been established in knockout mice. Therefore, adiponectin seems to be a marker of obesity-related diseases and a potential therapeutic target.
Obesity (Silver Spring) 2006 Feb
PMID:Metabolic actions of adipocyte hormones: focus on adiponectin. 1664 57


Obesity (Silver Spring) 2006 Feb
PMID:Why visceral fat is bad: mechanisms of the metabolic syndrome. 1664 58


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