Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0028754 (
obesity
)
124,988
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Conjugated linoleic acid (CLA) isomers,
c
9,
t
11-CLA and
t
10,
c
12-CLA, have been proved to exhibit excellent biomedical properties for potential use in anti-cancer applications and in reducing
obesity
.
Acer truncatum Bunge
(
ATB
), which is rich in unsaturated fatty acids, including oleic acid, linoleic acid, and nervonic acid, is a new resource for edible oil. In the present study, we developed a new method for producing two CLA isomers from
ATB
-seed oil by fermentation using
Lactobacillus plantarum
CGMCC8198 (
LP
8198), a novel probiotics strain. Polymerase chain reaction results showed that there was a conserved
linoleate isomerase
(LIase) gene in
LP
8198, and its transcription could be induced by
ATB
-seed oil. Analyses by gas chromatography-mass spectrometry showed that the concentration of
c
9,
t
11-CLA and
t
10,
c
12-CLA in
ATB
-seed oil could be increased by about 9- and 2.25-fold, respectively, after being fermented by
LP
8198.
...
PMID:Bioconversion of conjugated linoleic acid by
Lactobacillus plantarum
CGMCC8198 supplemented with
Acer truncatum bunge
seeds oil. 3026 97
