Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tuberculin sensitivity was studied in 668 apparently healthy schoolchildren six to seven years of age vaccinated B.C.G. before the age of one. Sensitivity was assessed using the standard dose of PPD and reactions with an area of erythema of 10 mm diameter or more were considered positive. The results were as follows: 1) The frequencies of tuberculin-positive children were 97 (31.3%) of 310 subjects in the fishing area, 21 (9.9%) of 213 in the farming area, and 35 (24.1%) of 145 in the intermediate zone. 2) Prevalences of the positive children by obesity index were 28 (36.8%) of 76 in the large, 72 (24.5%) of 294 in medium, and 53 (17.8%) of 298 in the small, and the decreasing tend in frequencies among these three classes by obesity index were statistically significant (p < 0.01). 3) Gender differences in frequency of tubereulin-positive children were not clearly detected when a comparative study grouped by obesity index and area was carried out. These observations suggest that tuberculin sensitivity in children may be influenced by the size of body mass and also characteristic factors, including diet, in their residential districts.
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PMID:[Tuberculin sensitivity among school children in Niigata Prefecture, Japan]. 984 59

The authors show the results of an integrated model for risk management of tuberculosis in a sample of sheltered homeless in Rome. Tuberculin skin test (TST) was used for evaluating the prevalence of latent infection (LTBI). In TST positives, expectorate was collected and chest X-ray was achieved. Multiple logistic regression analysis was performed to investigate determinants of infection. Out of 288 recruited subjects, 259 returned for the TST reading; 45.56% were positive and referred to a specialized center; 70 accessed the health facility and completed the clinical pathway. The risk factors associated to LTBI were male gender (OR = 3.72), age over 60 years (OR = 3.59), immigrant status (OR = 3.73), and obesity (OR = 2.19). This approach, based on an integrated social network, guarantees high adherence to screening (89.93%), allowing patients testing positive for latent tuberculosis infection to be diagnosed and rapidly referred to a specialized center.
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PMID:Tuberculosis in sheltered homeless population of Rome: an integrated model of recruitment for risk management. 2244 32