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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

50 patients were operated on; 42 women and 8 men at the age of 17 to 57. The weight of the patients was 100 to 184 kg. and the overweight amounted in most cases to 70 to 188%. Long lasting conservative treatment proved to be inefficient. The endocrynological basis of the obesity was excluded. 6 patients were operated upon according to the Salmon-method and 44 according to the Payne-De Wind-method. 3 patients died. 47 patients recovered without complications. For two years after the operation the loss of weight was 28 to 50% compared with the initial weight. Diarrhoe stopped six months after the operation. During this time a decrease in the concentration of potassium and calcium in the blood serum was observed. Judging from the positive changes the decrease of the cholesterol concentration in the blood was observed as well as the general improvement of the patients health. All patients are in good health and have taken up their jobs again.
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PMID:[Surgical treatment of obesity by jejuno-ileal bypass (author's transl)]. 86 29

Four experiments tested responsiveness to external and sensory stimuli in female human subjects who differed in degree of overweight and in age of onset of their obesity. The effects of weight loss upon external responsiveness were assessed by testing subjects before and after weight reduction in order to determine the role of energy deficit and deprivation in mediating heightened responsiveness to external cues. There was no significant positive correlation between degree of overweight and degree of external responsiveness. In general, the age of onset of the obesity was also not a relevant factor in the degree of externality. Weight loss did not change responses to visual and cognitive cue salience manipulations in measures of feeding, emotionality, time perception, and short-term recall, whereas responsiveness to variations in palatability increased following weight reduction. While external cue responsiveness does not appear to result from adiposity per se or from deprivation, responsiveness to taste stimuli may reflect these parameters. The role of external and sensory cues in the development and maintenance of obesity is discussed.
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PMID:Effects of degree of obesity, age of onset, and weight loss on responsiveness to sensory and external stimuli. 87 24

Longitudinal growth data on children who developed obesity during childhood reveal a distinct tendency for height gain to accelerate coincident with or after the onset of excessive weight gain. The magnitude of the relative height increment is related to the degree of overweight. Overnutrition accelerates growth, just as undernutrition retards it.
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PMID:Nutrition and growth. 87 62

The experience with group therapy of five obese persons over a ten-week period is being reported. The purpose was to effect changes in abnormal eating habits by means of behavioural methods toward self-control. The mean weight of the group was reduced from 79,4 kg to 72,2 kg during the period of the course; mean weight reduction was 7,2 kg while mean overweight was lowered from 22% to 10%. In order to prevent rebounds, it is recommended that participants remain under continued care. Despite the small number of probands, it is though that the study provides useful information about the effectiveness and problems of group-dynamic obesity treatment in population.
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PMID:[Experience in a group of overweight persons]. 87 59

Studies on height, weight and skinfolds in four anatomical regions have been made on groups of South African Black, Coloured, Indian, and White pupils of 17 years. Examination of weight for height compared with weight for age data have revealed high percentages of obesity particularly in non-White groups. Obesity is not only reflected in higher mean umbilical skinfold values found in the short, lighter urban Indian, also Coloured and Black girls, compared with taller, heavier White girls, but in high percentages of body weight as fat. There was an unexpected similarity of mean triceps skinfold values in the different ethnic groups. It is suggested that the problem of overweight and obesity in adolescent subjects, who remain underheight, whether from nutritional, genetic or adverse environmental factors, may be aggravated by school feeding schemes, as once the physiological demands of the pubertal growth spurt have been met, obesity is occurring in these former so called malnourished groups. The obesity occurs without dietary intervention.
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PMID:The bearing of height, weight and skinfold thickness on obesity in four South African ethnic groups of school pupils of 17 years. 88 15

More than 250 patients with extreme obesity were treated at the Chir. Univ.-Klinik Erlangen by 30 + 20 cm jejunoileostomy. The patients lose overweight and reach nearly normal weight after 9-12 months. Carbohydrate intolerance and hypertriglyceridema disappear. Ensuing malabsorption and also the surgical procedure are responsible for complications like wound infection or intussuception. The resulting chronic vomitting causes hypoproteinemia, hypokaliemia and liver dysfunction. Continuous therapeutical substitution is necessary, especially of potassium, to avoid deficiency. The diarrhea is treated by drug administration, i.e Reasec. The long time results are not yet sufficiently known. Calcium deficiency may occur many years later. The rate of cholelithiasis and nephrolithiasis ranges from 2 to 10%. The over-all lethality over 5 years is 2,8% as seen in the patients of our clinic during the past 6 years.
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PMID:[Internal complications following jejunoileostomy in the treatment of extreme obesity]. 88 50

20 obese subjects were compared with 20 controls with normal weight regarding their polymorphonuclear (PMN) granulocyte functions, and plasma lipids. The obese subjects showed a significantly decreased PMN bactericidal capacity, and increased PMN adherence. No differences were found in their mean PMN chemotaxis and opsonic capacity of plasma. The values of plasma triglycerides and free fatty acids were higher in the obese, while plasma cholesterol and phospholipids corresponded to the control values. The changes in granulocyte function did not correlate significantly to plasma lipid levels or to body weight and Broca's index in either group. --It is concluded that changes in granulocyte function occur in obesity, but are not related to plasma lipids or degree of overweight.
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PMID:Obesity, plasma lipids and polymorphonuclear (PMN) granulocyte functions. 90 68

The obesity belongs to the diseases with a great socio-medical importance. 75 patients with obesity were examined by means of the psychopathological short-time method issued by Hennig and Mehl, which was developed from Kincannon's mini-mult. Here in 30 obese patients (ca. 40%) increased values in at least one clinical scale appeared, which may be estimated as a reference to a neurotic mode of behaviour. Thus, neurotic modes of behaviour seem to appear more frequently in patients with obesity than in the average population (10%), however, more infrequently than in essential hypertonics (70%). Neurotic (Broca index + 30 kg) and non-neurotic (Broca index + 29 kg) patients with obesity had on an average the same overweight.
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PMID:[Psychological studies on adipositas]. 91 May 23

Spirometric, gasometric and electrocardiogarphic studies were carried out in 17 patients at rest, who were treated surgically for extreme obesity (overweight from 52 to 175 per cent in relation to the normal weight). The measurements were made before operation. It was found that the mean spirometric values were within the range of acceptable deviations from the normal value. The residual volume showed a tendency towards decreasing, especially in young patients. The values of dynamic parameters indicated a tendency towards ventilatory changes of a restrictive type in both groups. Minute ventilation at rest increased proportionally to obesity. Decreased values of respiratory equivalent indicated a good economy of respiration in obese persons when at rest. The mean gasometric values in capillary blood at rest were also within the acceptable range of abnormalities. Electrocardiographic tracings taken at rest showed considerable changes in the group of more obese persons.
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PMID:Spirometric, gasometric and electrocardiographic studies in patients with extreme obesity prepared for surgical treatment. 97 Jun 21

A physiological role for pleasure has been suggested from observations that glucose loads reduced pleasantness ratings for sweet stimuli in normal weight but not in weight-reduced subjects. This hypothesis was reexamined in fasting and food-loaded, lean and obese subjects. Magnitude estimates of sweetness and pleasantness were obtained for seven sucrose concentrations. Indices of obesity including percent overweight, percent body fat, and body mass index were calculated. Pleasantness ratings of fasting subjects either increased up to a moderate concentration and then declined (type I hedonic response) or increased monotonically with concentration (type II hedonic response). Both types of response were found in lean and obese subjects. Within each weight group there appeared a negative correlation between pleasantness response and indices of obesity. Caloric loads reduced hedonic ratings of type II lean and obese subjects, but did not affect pleasantness response of type I lean and obese subjects. These findings indicate the presence of an hedonic monitor biased by body weight and caloric intake. The data suggest a physiological role for pleasure in regulating body weight at different set points in lean and obese subjects.
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PMID:Effects of body weight and food intake on pleasantness ratings for a sweet stimulus. 97 36


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