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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The recognition and treatment of obesity has undergone marked changes in the past two decades. Along with the abandoning of the concept of exogenous obesity, the physician has discovered a variety of developmental, psychological, pharmacologic, socioeconomic, neurological, and genetic roots for the syndrome. The clinician has also found medical treatment modalities (fasting and behavior modification) that hold much more promise than traditional supportive relationships with dietary consultation and anorexogenic medications. Surgical treatment also, ileojejunal bypass, is gradually emerging as a treatment of choice for certain well-motivated, super-obese people for whom all other treatment modalities have failed. Future research into central serotonergic mechanisms offers hope that we can begin to know what it is that turns on hunger, turns off appetite, and regulates weight in such a stable manner over such a long period of time.
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PMID:Basic considerations in the treatment of obesity. 87 19

Sanatorium treatment for 27 days was carried out for 52 patients with obesity of alimentary metabolism type, consisting of moderate loading and high-protein, high-lipid diet with 2430 to 2840 cal daily, with unusually low carbohydrate contents--10 g for the first week and 38 g--in the fourth. The authors established a favourable total and an average daily body weight loss of the patients, irrespectively of the relatively high caloric intake. No sense of hunger was reported from the majority of the patients. The subjective complaints observed are more frequent and more severe, as compared with the other treatment regimens with reducing but balanced dietetic regimens. The majority of the subjective complaints established could be associated with the objectively confirmed compensated metabolic ketoacidosis. The unfavourable changes in the followed-up laboratory indices are: considerable decrease of blood sugar, massive ketonuria, elevation of serum uric acid and deviations in the acid-base parameters. Serum lipid indices fell under the effect of the treatment and body weight reduction. What impresses is the serum cholesterol reduction in spite of the high exogenic import, the diminution of cholesterol-lecithin index and the marked elevation of free fatty acid in serum, manifestation of incresed lipolysis in the lipid depots. (he diet indicated is not balanced and not physiological. It must be applied casually in obesity treatment. Its application is possible only after a strict assessment of each individual patient with obesity with no accompanying diseases, that do not agree with the partial fasting and cannot be included in intensive motor regimen.
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PMID:[Treatment of obesity with a high-protein, high-fat, "carbohydrate-free" diet]. 101 11

Observations of eating responses of obese and nonobese subjects were made in meal settings. Seven obese and seven nonobese male undergraduates were videotaped as they ate four dinner meals, two low and two high in preference, under low and high hunger conditions. As hunger and preferences increased, the amount of food eaten, the meal length, and the number of bites significantly increased. Time per bite decreased as hunger and preference increased. Obese subjects ate more grams per second than the nonobese subjects. Obese subjects also ate more high preference food and less low preference food than nonobese subjects. These findings are discussed in terms of Schachter's theory of differential stimulus orientation of obese and nonobese people and in terms of the set-point theories of Nisbett and Sclafani and Kluge.
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PMID:Eating responses of obese and nonobese humans during dinner meals. 116 27

This article reports on the treatment of 21 obesity patients employing auricular acupuncture. The auricular points used were Mouth, Shen-men, Stomach, Hunger and Spleen, and the period of treatment lasted from two to six weeks. The weight loss in these patients varied from 2 to 16 pounds. The rationale for using these points and cautions for this type of treatment were discussed.
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PMID:The treatment of exogenous obesity employing auricular acupuncture. 119 Jan 18

Our knowledge of hunger and bodyweight regulation is gradually increasing. There are wide interindividual variations in nutritional needs and therefore in susceptibility to gross overweight. Obesity is associated with disturbances in neurosensorial, hormonal and metabolic regulations which are now much better understood. Studies of certain ethnic groups in which obesity is particularly prevalent contribute to the genetic approach to the condition. As in animals, where obesity models correspond to mono- or polygenic transmissions, it is probable that in human beings obesity is a syndrome with multiple causes.
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PMID:[Physiopathology of human obesity]. 128 68

Obesity is regarded in its triple connotation of symptom, risk factor and homeostatic organization, stressing the inadequacy of traditional formulations about psychological causation. Psychological factors most frequently associated to obesity are excessive intake, complications of dieting and alterations of body image. The predictive role of psychophysiological dimensions of Restraint, Disinhibition and Hunger is discussed on the basis of empirical information. ICD-10 formulations are considered a positive advance in the taxonomy of syndromes with alterations of body weight.
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PMID:[Obesity and feeding behavior: diagnostic and psychometric aspects]. 130 61

Sodium excretion and the blood levels of aldosterone, renin, atrial natriuretic peptide (ANP), and insulin were investigated in 9 women with obesity of alimentary-constitutional type during hunger therapy and resumed nutrition. It has been assumed that restricted sodium excretion with the kidneys during fasting is mainly caused by activation of the renin-angiotensin-aldosterone system, with ANP contributing to it, insulin not playing the major role in this process.
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PMID:[Hormonal regulation of sodium excretion by the kidneys during hunger therapy of obese patients]. 138 80

Ninety-five female university students completed Stunkard and Messick's (Journal of Research Psychosomatic Research, 29, 71-83, 1985) Three-Factor Eating Questionnaire, measuring three dimensions of human eating behavior: cognitive restraint, disinhibition, and hunger susceptibility. They were led through the visualization of a neutral or pleasant scene and a food scene, but were instructed that they would not be able to eat the food. Only hunger susceptibility was found to be significantly correlated with ratings of subjective anxiety (SUDS) and urge to eat in the not eating situation after any variability associated with the neutral scene was removed. That is, internal (hunger) and external (incentive) cues when linked to not eating are sources of anxiety. Treatment programmes for obesity might well include desensitization of these cues.
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PMID:Dietary restraint anxiety and its relationship to human eating behavior. 146 Jan 3

The periodical food intake (discrete meals) demands a control system, which includes signals for hunger and satiety. Satiety and hunger change with the absorptive and postabsorptive state of the delivery of nutrients to the organism. The brain areas involved in the regulation of food intake receive informations from three sources: periphery, environment and memory. Hypothalamic structures and pathways of neurotransmitters are considered especially. Beside these, the limbic structures are mainly responsible for the development of motivated feeding behaviour. Disturbances in the regulation of feeding behaviour are prone to cause obesity and anorexia nervosa.
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PMID:[Neural regulation of food absorption--review]. 159 68

This paper selectively reviews available evidence concerning psychological characteristics associated with obesity, psychological changes accompanying very-low-calorie diets (VLCDs), and the influence of certain psychological factors on response to VLCD treatment. The obese population as a whole does not show an elevated incidence of psychopathology. Treatment-seeking obese do show more psychiatric disturbance, at a level comparable to other medical/surgical patients. There appear to be no global personality traits or profiles that are associated with obesity. However, obese people differ from non-obese groups on psychological and behavioral variables related to weight and eating and more frequently display perceptual and emotional body image anomalies. Binge eating appears rather common among obese groups. VLCDs have generally neutral to positive effects on hunger, depression, and anxiety. New data on body image suggest that VLCDs are associated with post-treatment underestimation of body size. Finally, recent data on possible psychological and behavioral correlates of VLCDs outcome are presented.
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PMID:Psychological aspects of obesity and very-low-calorie diets. 161 81


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