Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

3 cases of retinal thrombosis in young patients on oral contraception (OC) are presented. Pathology disappeared completely as soon as the patients changed contraceptive method. Retinal thrombosis can be arterial or venous, but the incidence is not clear. The major complication with treatment with OC is cerebrovascular thrombosis, which also could be arterial or, more rarely, venous. The mechanisms causing such effects are not completely clear; it is known that OC increases hypercoagulability in 25-30% of women on OC, and that it diminishes the antithrombin 111 factor. Risk factors, such as familiar antecedents of thrombosis, phlebitis, obesity, arterial hypertension, smoking, age over 40, are all strong contraindications to OC. The authors also report on the abundant literature on this subject.
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PMID:[Neuro-ophthalmologic accidents caused by hormonal contraception]. 75 8