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Query: UMLS:C0028754 (obesity)
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Overweight and obesity trends were investigated for schoolchildren and adolescents in Jeddah using data from 1994 and 2000. Individuals aged 10-20 years were selected using multistage stratified random sampling and direct measurements were made of body weight and height. Percentiles were calculated for body mass index (BMI), body weight and height for specific age and sex strata. For both sexes, BMI increased between 1994 and 2000 at the 50th percentile but higher still at the 85th and 95th percentiles. The increase in body weight and BMI were marked for all age groups; however boys showed the largest increase aged 10-16 years, whereas girls showed the lowest at 14-16 years. Public health intervention is crucial to prevent or reduce overweight and obesity among youth.
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PMID:Overweight and obesity among Saudi Arabian children and adolescents between 1994 and 2000. 1560 27

Two recently published reports from American Heart Association and National Heart, Lung, and Blood Institute have addressed the management of the metabolic syndrome. It is of importance to present the content of these reports and to discuss the management of the metabolic syndrome in Swedish health care. Today there are official definitions of the metabolic syndrome from the US and also definitions issued by the WHO. The American criteria have been developed with the aim to be used in clinical practice whereas the definitions from the WHO are partly based upon examinations, which are not routinely used in the routine care. The metabolic syndrome is common among men and women and increases in parallel with increasing age. Overweight and obesity are among the most important factors in the syndrome, which may be expected to increase because of the increasing incidence of obesity. The metabolic syndrome according to the two definitions has in several studies been shown to strongly increase the risk for type 2 diabetes and are also associated with an increased risk of cardiovascular disease and death. Treatment of the syndrome must first of all be focused on changing diet and physical exercise habits. Drug therapy can be used for individual components in the syndrome such as hypertension, dyslipidemia, and hyperglycemia. Although there is still a need of further research in order to develop the knowledge of underlying mechanisms, improve risk assessment and treatment, there are now sufficient data and experiences to introduce the concept of the metabolic syndrome in clinical practice in the Swedish health care.
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PMID:[The metabolic syndrome--time to introduce the diagnosis in routine health care? Reflections on a current American report]. 1563 Dec 25

In excess of 50% of adult population and nearly one third of children in Mexico have overweight and obesity. This accounts for slightly >32,671,000 million persons, excluding children; thus, total numbers are even more significant. These figures are alarming for those responsible for the economic future and well-being of Mexico. Overweight and obesity lead to higher risk of mortality as well as development of multiple diseases, mainly coronary heart disease, diabetes type 2, cancer, and stroke, which are at present the principal causes of mortality in Mexico. The World Health Organization (WHO) announced that there are throughout the world more than one billion adults with overweight, of whom 300 million have obesity. In addition to the obesity epidemic in Mexico, there is high prevalence of diabetes type 2. Coexistence of both epidemics has been denominated the twin epidemic. As many as 80% of cases of type 2 diabetes are linked with overweight or obesity, particularly abdominal obesity. The disease was once thought to be limited to adults, but obese children are now developing the illness. In Mexico, we are able to refer to at least three epidemics, because not only are obesity and type 2 diabetes advancing rapidly in the country, but also cardiovascular disease, linked with high prevalence of both hypertension and metabolic syndrome as reported by scientists based on Mexican National Health Survey 2000 data.
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PMID:[The epidemiology of obesity]. 1564 67

Obesity has become an epidemic problem in Western societies contributing to several disease processes including metabolic diseases, hypertension, and cardiovascular disease. Overweight and obesity are frequently associated with increased plasma levels of aldosterone suggesting a direct link between obesity hypertension and increased mineralocorticoid levels. The adipocyte has long been suggested to be directly involved in the regulation of the body's homeostasis and recent evidence now proves that human fat is a highly active endocrine tissue. We therefore tested the hypothesis that adipocyte secretory products directly stimulate adrenocortical aldosterone secretion. Indeed, secretory products from isolated human adipocytes strongly stimulated steroidogenesis in human adrenocortical cells (NCI-H295R), as well as in bovine adrenocortical cells with a predominant effect on mineralocorticoid secretion. In conclusion, a possible direct link exists between fat tissue metabolism and adrenal mineralocorticoid secretion that may be responsible for obesity-related hypertension.
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PMID:Fat cells may be the obesity-hypertension link: human adipogenic factors stimulate aldosterone secretion from adrenocortical cells. 1566 38

A growing organism needs to have a steady availability of nutrients, in suitable quantities and in correct ratios, in order to achieve its genetic potential. Overweight and obesity in growing individuals may conceal lack of one or more nutrients. Obesity in childhood is the consequence of an excess of calories compared with the energetic waste because of the interlacing of genetic factors, metabolic factors (cellularity of the adipose tissue, deficit of thermogenesis), excessive food intake, alteration of some neuro-endocrine mechanisms which regulate bodily weight (set point theory), lack of suitable physical exercise; therefore a complicity of endogenous, exogenous, biological, psychological and social factors to which we cannot ascribe singularly a primary role. It is however necessary to start, since the first year of a child's life, a food education program as the latest acquisition shows that degenerative pathologies of metabolism start in a very precocious age and unbalanced nutrition starts since childhood. The most suitable therapeutic approach is that which takes in consideration all the aspects of obesity. This requires an intervention on several aspects: food, psychological mechanisms which sometimes are the cause of hypernutrition, attitude towards physical exercise, and also family and social behaviors concerning the patient. The traditional diet approach towards childhood obesity is based on balanced hypochaloric diets which provide about 1200-1800 kcal per day, distributed in 4 or 5 daily meals. The correct meal division educates the child to self-control and it is advantageous from a metabolic point of view because it avoids both high instability of glyco-insulin, caused by an excess of food, and because improving thermogenesis, induced by the diet, the result will consist in an increase of energetic waste. For the main meals it is advantageous to apply to a main course.
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PMID:[Dietetic indications for obesity treatment in childhood]. 1570 60

Childhood obesity is considered pandemic with significant social and economical costs because of its high morbidity and mortality. To evaluate the association between biological and environmental factors and infantile arterial hypertension (AH), a cross-sectional study was performed with 701 children, ranging from 5 to 9 years old, from Feira de Santana, BA. The arterial pressure was measured following the criteria of the Update on the 1987 Task Force Report on High Blood Pressure in Children and Adolescents. Overweight and obesity were defined as body-mass index equal or above the 85th and the 95th percentiles for age and gender, respectively. Interviews with the children's responsible were used to determine the role of gender, ethnic group, age, familiar history of AH, and type of school. Overweight (OR= 4.49; rho= 0.04), obesity (OR= 13.05; rho= 0.000) and studying at private school (OR= 1.93; r= 0.13) were observed as predictive and independent factors associated with hypertension. Therefore, biological and environmental factors seem to be involved on the genesis of AH in children.
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PMID:[Environmental and anthropometric factors associated with childhood arterial hypertension]. 1576 59

The purposes of this systematic review were to present and compare recent estimates of the prevalence of overweight and obesity in school-aged youth from 34 countries and to examine associations between overweight and selected dietary and physical activity patterns. Data consisted of a cross-sectional survey of 137 593 youth (10-16 years) from the 34 (primarily European) participating countries of the 2001-2002 Health Behaviour in School-Aged Children Study. The prevalence of overweight and obesity was determined based on self-reported height and weight and the international child body mass index standards. Logistic regression was employed to examine associations between overweight status with selected dietary and physical activity patterns. The two countries with the highest prevalence of overweight (pre-obese + obese) and obese youth were Malta (25.4% and 7.9%) and the United States (25.1% and 6.8%) while the two countries with the lowest prevalence were Lithuania (5.1% and 0.4%) and Latvia (5.9% and 0.5%). Overweight and obesity prevalence was particularly high in countries located in North America, Great Britain, and south-western Europe. Within most countries physical activity levels were lower and television viewing times were higher in overweight compared to normal weight youth. In 91% of the countries examined, the frequency of sweets intake was lower in overweight than normal weight youth. Overweight status was not associated with the intake of fruits, vegetables, and soft drinks or time spent on the computer. In conclusion, the adolescent obesity epidemic is a global issue. Increasing physical activity participation and decreasing television viewing should be the focus of strategies aimed at preventing and treating overweight and obesity in youth.
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PMID:Comparison of overweight and obesity prevalence in school-aged youth from 34 countries and their relationships with physical activity and dietary patterns. 1583 63

Overweight and obesity are a public health problem worldwide affecting adults and children as well. The aim of this study was to assess overweight, lipid profile and cardiovascular risk ratios in 390 preschool children from low socio-economic level from Valencia, Venezuela. Nutritional anthropometric evaluation measured by body dimensions, and serum determination of cholesterol, triglycerides, HDL-cholesterol, LDL-cholesterol and cardiovascular risk factors, were determined. 95% of the children were in relative and critical poverty. 14.3% of undernutrition and 20.8% of overweight was found. Lipid profile was in normal range, with no significant differences by sex, but higher values for HDL-cholesterol and risk ratios were found in children aged 1 to 3.99 years. Even though no differences were found by nutritional status, overweight children had higher values for lipids, except HDL-cholesterol. 6.3% of overweight children had cholesterol > or =170 mg/dL, 16.5% LDL-cholesterol > or =110 mg/dL, 40.5% triglycerides > or =75mg/dL and 100% HDL-cholesterol <45 mg/dL. Overweight and lipid profile alterations were present in an important group of the children, which increase their risk of obesity and chronic non-transmissible diseases. Nutritional and educational intervention should be addressed.
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PMID:[Lipid profile from low socioeconomic level preschool children. Valencia, Venezuela]. 1591 80

This study determined the prevalence of overweight, overall and central obesity in female adolescents and women and their possible association with marital status, occupation, literacy, parity, daily meal and snack consumption. The study was a cross-sectional, random survey of households. Rural and urban areas of Islamshahr district in Iran were selected and 1003 female adolescents and women aged 10-65 years were studied. The frequency of overweight and obesity were similar in rural and urban areas. On the basis of body mass index (BMI), more than 19% of adolescents were overweight or at risk of it and 66.8% of adult females were overweight or obese. Frequency of central obesity [waist to hip ratio (WHR) > or = 0.85]was 35.7% in all females. The mean BMI was significantly higher in married women and in women with less than 8 years of formal education. The mean WHR was significantly higher in women with less than 8 years of education or with more than 6 parity female adults. In addition, the mean BMIs and WHRs were significantly higher in women without any daily snack consumption. Overweight and obesity was very common in adult females of Islam shahr thus prevention of overweight and obesity through a healthy diet and increased physical activity should now be an important priority area.
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PMID:High prevalence of overweight and obesity in women of Islamshahr, Iran. 1592 35

Overweight and obesity present significant public health concerns because of the link with numerous chronic health conditions. Excess body weight is a result of an imbalance between energy intake and energy expenditure. Physical activity is the most variable component of energy expenditure and therefore has been the target of behavioral interventions to modify body weight. It appears that physical activity is an important component on long-term weight control, and therefore adequate levels of activity should be prescribed to combat the obesity epidemic. Although there is evidence that 30 min of moderate-intensity physical activity may improve health outcomes, the amount of physical activity that may be necessary to control body weight may be >30 min/d. There is a growing body of scientific literature suggesting that at least 60 min of moderate-intensity physical activity may be necessary to maximize weight loss and prevent significant weight regain. Moreover, adequate levels of physical activity appear to be important for the prevention of weight gain and the development of obesity. Physical activity also appears to have an independent effect on health-related outcomes when compared with body weight, suggesting that adequate levels of activity may counteract the negative influence of body weight on health outcomes. Thus, it is important to target intervention strategies to facilitate the adoption and maintenance of an adequate amount of physical activity to control body weight.
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PMID:Physical activity considerations for the treatment and prevention of obesity. 1600 26


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