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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The authors investigated the development of body weight of the population from six districts in the Czech Republic participating in the international WHO project MONICA. The examinations were made within the framework of epidemiological studies of risk factors of IHD in 1985 and 1988 in 1% independent population samples (range 25-64 years). The mean values of body mass index, BMI, increased in the above three-year period in men from 26.9 to 27.5 (p less than 0.001) in women from 26.9 to 27.4 (n. s.). The prevalence of obesity increased during the same period from 19.9% to 25.4% (p less than 0.001) in men and from 33.8% to 35.7% (n. s.) in women. In all decades of men and women there was a rising trend of body weight and increasing prevalence of obesity. With regard to the adverse effects of overweight on health and life span, the authors consider prevention of obesity as one of the foremost tasks of preventive medicine.
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PMID:[Trends in body weight in the population of the Czech Republic]. 220 44

The occurrence of risk factors for ischaemic heart disease in obesity is discussed. The presented view is based on the review of literature and own preliminary experiences. The importance of the distribution of the fatty tissue was shown for the medical practice. Android-type obesity increases the probability of the occurrence of metabolic disturbances leading to ischaemic heart disease.
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PMID:[Obesity as a risk factor for ischemic heart disease]. 221 32

Based on postmortem records at the Wayne County Medical Examiners' Office from 1982 to 1986, autopsy results indicated that the deaths of 129 persons aged 20-34 resulted from heart disease: 51 of these deaths were attributed to atherosclerotic cardiovascular disease (ASCVD), 29 to hypertensive cardiovascular disease, 28 to cardiomyopathy, and 21 to other cardiac causes. The majority of the deaths due to ASCVD occurred among men, both black and white, followed by black women, and the incidence increased with age. All of these deaths due to ASCVD were sudden and accounted for all deaths due to ischemic heart disease in this age group among Wayne County residents. Diabetes mellitus, left ventricular hypertrophy, a history of seizures, and the recent ingestion of alcohol were all found to be associated with sudden death from ASCVD in this group. Obesity did not seem to be a significant factor. These data suggest that ASCVD is not rare as a cause of death in young adults and some of the risk factors identified in older subjects also operate in this age group.
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PMID:Atherosclerotic cardiovascular disease and sudden deaths among young adults in Wayne County. 222 Jul 3

Diabetes mellitus is one of the most common chronic diseases affecting the elderly in the United States. It has been diagnosed in 9.6% of people 65 years of age and older, and an additional 9.3% meet oral glucose tolerance test criteria for the disease but have not been diagnosed. Taken together, diagnosed and undiagnosed diabetes affects almost one in every five people 65 years of age and older. An additional 23% of the elderly meet diagnostic criteria for impaired glucose tolerance, a condition that conveys excess risk for macrovascular disease. Prevalence of diagnosed diabetes in the elderly is expected to increase 44% in the next 20 years, to an estimated population of 3.9 million people. Elderly people with diabetes make an average of 3.7 visits per year to physicians specifically for care of their diabetes. Over 80% of this care is delivered by general and family physicians and internists. About 30% of diabetics 65 to 74 years of age are hospitalized each year, a rate that is almost twice that of elderly people without diabetes. Cardiovascular and peripheral vascular complications are often twice as prevalent as among people without diabetes. Risk factors for macrovascular disease are also highly prevalent among the elderly, including obesity, hypertension, and hypercholesterolemia. Three fourths of deaths of diabetic patients 65 years of age and older are caused by diseases of the circulatory system, primarily ischemic heart disease and stroke. The death rate from cardiovascular disease among elderly diabetic patients is twice that of people without diabetes in the same age range.
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PMID:Epidemiology of diabetes mellitus among the elderly in the United States. 222 42

In a group of 70 probands treated on account of ischaemic heart disease manifested before the age of 55 years and in the grade I and II offspring the presence of other risk factors of the disease was assessed--smoking, arterial hypertension, obesity and diabetes mellitus. This part II is a continuation of the previous paper where the ratio of hyperlipoproteinaemias in the group was assessed. The probands comprised 62.9% smokers, 25.7% hypertonic subjects, 68.6% obese subjects and 20% diabetics. Risk factors were found only in grade I offspring--29.4% smokers, 2.4% hypertonic subjects and 16.7% obese subjects. The author emphasizes the fact that almost 40% of the offspring under 35 years of age with a family-history of early ischaemic heart disease have at least one risk factor of the disease.
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PMID:[Risk factors in persons with early manifestations of ischemic heart disease and in their offspring. II. Additional risk factors]. 222 95

In 102 patients with ischemic heart disease the severity of stenosis was classified into 7 grades (0, 25, 50, 75, 90, 99, 100%) in accordance with the AHA reporting system. The coronary angiograms were compared at first and second catheterization (intervals 2-84 months) and progression was considered present if the stenosis in the second study showed more than one grade increase in comparison with the first study. Fifty six patients met criteria for progression. Risk factors were obtained within the first second catheterization. Drug and diet therapy were evaluated by interview. No significant difference could be found between the progression (P) group and the nonprogression (N) group in relation to family history and obesity. A history of hypertension was more common in the P group. In respect to blood sampling, the values of total cholesterol, Apo B, CII, E and Apo B/AI were significantly higher in the P group than those in the N group at first and second catheterization. The percentage of patients showing abnormal levels of blood sugar and lipid were higher in the P group than the N group although the percentage of patients with drug and diet therapy were higher in the P group than in the N group. The percentage of patients with diet therapy for hyperglycemia and hyperlipidemia were higher in the P group, however weight increase was more common in the P group. These data suggest that sufficient diet and drug therapy is necessary for patients with risk factors.
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PMID:[Prevention of progression of coronary atherosclerosis by drug and diet therapy]. 223 14

The current decade has witnessed an increasing interest in the diet-cancer issue as a central one for public health. Notwithstanding a substantial amount of epidemiological investigations, firm evidence of carcinogenicity exists only for alcoholic beverages with respect to cancers at several sites, and for aflatoxin with respect to liver cancer; also, the relation is established between diet related excess of energy intake, as translated into obesity, and cancer of endometrium and gallbladder. For a number of other dietary factors the evidence for a causal or protective role still remains at a presumptive level (e.g. intake of fresh vegetables and fruits with respect to cancers at several sites), or is still frankly open to debate (e.g. fat with respect to breast and colon cancer). Methodological inadequacies in past studies have been identified and clearer results should derive in the coming decade from epidemiological investigations substantially improved in methodology, particularly from the long-term prospective studies as now planned by the International Agency for Research on Cancer. Fortunately for cancer prevention, such dietary advice as can be derived from the highly incomplete and unsatisfactory knowledge on the role of dietary factors on cancer, turns out to be in broad agreement with the advice aimed at preventing other major diseases such as ischaemic heart disease and hypertension. This allows the issuing of a set of simple but important 'prudent diet' recommendations.
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PMID:The diet and cancer hypothesis: current trends. 223 43

The prevalence of diagnosed diabetes in Aboriginal people living in central Australia (population, 9983) was determined by collating data from the hospital, rural and urban health services, nursing homes and death registers. A total of 98 male and 183 female Aboriginal residents with diabetes attended health services in central Australia between January 1984 and December 1986. The point prevalence of diagnosed diabetes at the end of 1986 in the age group 25-34 years was 1.6% in men and 3.1% in women, and in those over 35 years, 8.8% and 14.1%, respectively. The true prevalence of diabetes (diagnosed and undetected) is likely to be at least twice this rate, and constitutes a major public health problem in central Australia. Diabetes and other disorders such as obesity, hypertension and ischaemic heart disease have common antecedents and outcomes. The control of these non-communicable diseases requires integrated and culturally appropriate educational, social and medical strategies.
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PMID:Diabetes among aboriginal people in central Australia: a high prevalence based on health service attendance. 223 48

The association of hypertension, diabetes mellitus and abnormal lipoprotein patterns suggests that this combination has a lethal effect with regard to vascular disease. It is therefore necessary to do something about the known lifestyle factors such as cigarette smoking, obesity and possibly a low fibre diet. The high incidence of ischaemic heart disease among emigrant Indians in South Africa and Trinidad, and the low incidence in blacks of South Africa and the West Indies, suggests that there may be different thresholds for susceptibility to disease in various ethnic groups, beyond which the risk factors begin to operate.
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PMID:Hypertension and vascular disease in India and migrant Indian populations in the world. 225 88

Evidence has been provided that adequate physical activity prevents diseases caused by hypokinesia (hyperlipoproteinaemia, ischaemic heart disease, myocardial infarction, obesity and to a certain extent also hypertension) and that it retards the ageing process, in particular osteoporosis. It prolongs thus active life and life in general. The majority of our population suffers from lack of exercise. It is therefore necessary to promote activity and sports not only in healthy young people (in particular with a sedentary occupation) but also in older people. And in the latter group in particular in those with a mild degree of ischaemic heart disease, mild hypertension, in obese subjects, diabetics and those who come from families where these diseases occur. Even when the disease is already advanced or a relapse is imminent, a certain amount of physical activity, controlled by sports doctors on agreement with the attending physician is indicated. Sports Consulting clinics, since the foundation of the first one in 1924, served all sportsmen and visitors. During the totalitarian regime district and regional departments of sports medicine were established as well as an Institute of National Health for top sports but their activities were restricted only to contesting sportsmen and professionals. During the foreseen reorganization of health care the care of sports doctors most be extended to comprise also the above mentioned groups of non-contesting people and subjects at risk. This will be possible only if sports medicine will be included in primary health care and if eventually a department of sports medicine will be established in every institute of national health. It will serve not only sportsmen but the public as a whole.
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PMID:[Perspectives in sports medicine in Czechoslovakia]. 226 21


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