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Query: UMLS:C0028754 (obesity)
 124,988 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

On the Surgery Department of Military Hospital in Zagreb 164 cases of acute pancreatitis, among them 88 male and 76 female, were treated during the period of 1963 to 1974. Diagnosis was based on anamnesis, clinical symptoms, laboratory tests as well as X-ray pictures of the lungs and abdomen. In most cases (72,5 percent) etiology of the disease has shown changes of biliary tract; obesity and alchoholism were also present in high percentage. Operative treatment was applied in 72 cases and 92 cases have undergone conservative treatment. Indications for surgical intervention were lithiasis, cholecystitis, inefficiency of conservative therapy during the first 12 hours and such cases in which diagnosis could not have been given with sufficient certainty. Along with usual surgical treatment in 23 cases in which biliary obstruction and serose pancreatitis were present choledochoduodenostomy was applied with satisfactory results. 28 patients died out of 164; mortality percentage 17,1.
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PMID:[Acute pancreatitis in our case reports]. 30 Sep 74

The most important side effects of oral contraceptives (OCs) and their incidence, together with advice and monitoring of the patient at risk, are pointed out. There is a mild increase in blood pressure in longterm contraceptive use caused by increased angiotensinogen production by the liver. It is significant only for women with a history of familial hypertension, diabetes mellitus, or pre-eclampsia. Smoking increases this risk. Urinary tract infections are 25-50% more frequent in pill users. Glucose tolerance is slightly decreased. Contraceptives' diabetogenic effect is higher in women with hereditary tendency for diabetes, latent diabetes, and/or obesity. They are contraindicated in latent diabetes. Findings are contradictory in their effects on cholesterol and triglyceride serum level, but the pill is contraindicated in lipid metabolism disorders. There is an increased incidence in cholecystitis and cholelithiasis in pill-users (70-80 additional cases/100,000 user years). Liver diseases, intrahepatic cholestasis, occur rarely and benign liver tumors have not conclusively been proved to be caused by the pill. A variety of laboratory findings have been related to contraceptive use and drug interactions occur with barbiturates, rifampicin, hydantoin, and phenylbutazone. Blood coagulation is increased, partially by increased production of various blood coagulation factors; but more importantly, by a decreased synthesis of antithrombin III, a natural protective mechanism against intravascular coagulation. This increases thrombosis risk. Risk doubles with simultaneous cigarette smoking. Various epidemiological studies indicate a 5-10 fold increase in thromboembolism and thrombophlebitis, deep vein thrombosis, and pulmonary embolism. There is a correlation between contraceptive use and cerebrovascular disorders and myocardial infarction. This risk increases with age and years of pill use. The pill is contraindicated with symptoms of thrombophlebitis and thromboembolism, sickle cell anemia, proposed surgery, and longterm immobilization. Overall risk factors are not too high. Recommendations for rational pill use related to age are given and further contraindications are mentioned.
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PMID:[Adverse effects of oral contraceptives]. 55 52

A 12 year old boy is presented with choleithiasis and cholecystitis diagnosed by oral cholecistogram and intravenous cholangiogram and managed surgically with a cholecystectomy. A review of 667 cases of cholelithiasis in children is presented from literature, since the first report of gallstones in 1737, until 1975. It is showed that childhood cholelithiasis is a uncommon disease, occurring in all ages but (commoner) in preadolescent and adolescent girls. Etiologic significance of obesity, family history of cholelithiasis, pregnancy and history of previous abdominal surgery is reported. Haemolytic disease is an underlying etiologic agent in less than 19% of 416 cases reviewed. A high percentage of gallstones were visible on plain films of the abdomen and oral cholecystograms were diagnostic of cholelithiasis or showed changes highly suggestive of gallstones in 86% of cases reviewed. In a child with abdominal pain of unknown etiology, it is imperative to exculade the possibility of gallstones, and plain films of the abdomen and oral cholecystography are the best investigative techniques to do this.
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PMID:[Gallstones in children. Report of one case and review of the literature (author's transl)]. 102 30

The results of the study have shown that the nutrition of rural population is characterized by excessive consumption of bread and baked products, by high content of phosphorus, magnesium and iron, low content of animal proteins, vegetable oils, calcium, vitamins A, ascorbic acid and riboflavin. The incidence of cardiovascular, respiratory and alimentary diseases in this group of population was rather high. The nutrition of students is characterized by excessive consumption of polysaccharides, vegetable oils, thiamine, niacin, ascorbic acid (in winter-spring period), and calcium. Diseases associated with nutrition disorders (obesity, hepatitis, cholecystitis, colitis) are most often recorded in this group of population.
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PMID:[Actual nutrition and health of several groups of rural and urban population of the Republic of Georgia]. 138 91

To evaluate the likelihood that patients can be discharged from the hospital the day after open cholecystectomy, a prospective study of 500 consecutive patients undergoing cholecystectomy was undertaken. The study group included patients with associated acute and gangrenous cholecystitis, biliary pancreatitis and choledocholithiasis as well as those with diabetes, hypertension and obesity. Approximately one-fourth of the total group were discharged within 24 hours and over one-half in 48 hours. There was a significant correlation between advancing age and increasing length of stay. Almost one-half of the patients less than 35 years of age without acute or complicated disease were discharged within 24 hours, more than 80 per cent within 48 hours, and the mean length of postoperative stay (MLS) for these patients was 1.9 days. The presence of choledocholithiasis and fever greater than 101 degrees F. increased MLS, while acute cholecystitis, hyperamylasemia and leukocytosis did not. Early discharge from the hospital after open cholecystectomy, even in sick patients, is safe and cost-effective.
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PMID:Twenty-four hour hospitalization after cholecystectomy. 194 86

Findings from studies showing an increased incidence of gallstones in diabetic patients do not control for other variables, such as obesity. There is no proof that diabetic patients have more gallstones. Gallstones do not cause diabetes mellitus. The principal gallbladder pathologic feature in diabetic patients is a functional deficit of uncertain etiologic factors, creating a large, flaccid, poorly emptying organ. Bile acid and lipid composition are usually increased in diabetic patients. Cholecystitis seems to be a more serious disease in diabetic patients, with worse infectious sequelae and more rapid disease progression. This conclusion has not been examined statistically. Even with modern care, the complication rate for operations upon the biliary tract in patients with diabetes is increased. Those with diabetes are generally older than other patients requiring cholecystectomy. Systemic changes of aging partly explain increased morbidity and mortality. Diabetic patients with symptomatic gallbladder disease usually require operation. Risk of cholecystectomy in diabetic patients is similar to that in nondiabetics. Prophylactic cholecystectomy for diabetic patients with "silent" gallstones was formerly recommended because of an apparent high risk of cholecystitis. Until the natural history of gallstones in those with diabetes has been defined, such patients should be considered in danger of serious illness. The risk of acute cholecystitis in diabetic patients with stones is probably significant enough to warrant the performance of early cholecystectomy.
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PMID:Gallstones, cholecystitis and diabetes. 224 90

Seventy-five cases of coronary heart disease with gallstones and another 75 cases without gallstones as controls were studied. The positive rates of previous cholecystitis and chronic intestinal diseases, and familial history of gallstone in the first group were obviously higher than those in the control group (P less than 0.05 & 0.11). The odd ratio (OR) was 4.22, 9.00 and 6.00, respectively. There was no difference in high serous lipid level, obesity, high cholesterol and fat intake (P greater than 0.05) neither group took clofirrate. It demonstrated that susceptible factors for coronary heart disease patients to develop gallstones are probably the same as in general population. The imbalance of lipoid metabolism had no direct associate with gallstones. The synergistic action of the imbalance of lipid metabolism and administration of some kinds of medicine might be a susceptible factor for coronary heart disease patients to develop gallstones.
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PMID:[Matched investigation of risk factors in coronary heart patients with gallstones]. 232 44

Cholecystitis and cholelithiasis are infrequent in children and have been historically associated with adolescent pregnancy or hemolytic disorders; however, the incidence and spectrum of cholelithiasis seem to be changing. Between 1970 and 1988, 47 children 17 years of age or less underwent cholecystectomy for cholecystitis or cholelithiasis in our hospital. The patients were divided into chronologic groups: Group 1 encompassed 1970 through 1979 (15 patients) and group 2, 1980 through 1988 (32 patients). The groups were compared for age, sex, pregnancy, blood dyscrasia, family history, obesity, use of total parenteral nutrition (TPN), and incidence of choledocholithiasis with its sequelae. A significant increase in the number of patients with cholelithiasis was found. Infants and young children were affected more frequently in group 2, and many of these young patients had a history of TPN. Choledocholithiasis was also more common in group 2 and presented with life-threatening sequelae. Calculous biliary tract disease should be considered as a possible cause of abdominal pain in children. Timely operative intervention can prevent the increasingly common sequelae of childhood cholelithiasis.
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PMID:Changing spectrum of cholelithiasis and cholecystitis in infants and children. 251 75

The Walnut Creek Contraceptive Drug Study which began in 1968 and ended in 1972, monitored 16,638 women as part of a multiphasic health checkup and collected information on oral contraceptive (OC) use; smoking, alcohol use; other habits, and family and medical histories. The number of women years was determined in each age and weight category. The rates of gallbladder disease were similarly calculated. The Cox proportional hazards model was utilized as implemented in the multivariate life table analyses. In addition, Quetelet's body mass index as a measure of obesity was applied. 16,240 women had an intact gallbladder; of these 432 were hospitalized with diagnosis of gallbladder disease. The diagnosis was confirmed in 423 women: 98% had cholelithiasis accompanied by pathologic evidence of cholecystitis. The gallbladder disease rate increased with age, with body mass index, and it was dramatically higher in women in the highest quintile of Quetelet's body mass index than in other quintiles at all ages. A nonlinear association of cholecystectomy with obesity persisted. At least 500,000 cholecystectomies are carried out in the US annually, and the risk is much higher in women in the uppermost quintile, thus it is reasonable to suggest that preventive efforts should focus on this group.
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PMID:Obesity and cholecystectomy among women: implications for prevention. 322 28

Physical conditioning induces many favourable changes in the body, including an increase of maximum oxygen transport, a decrease of body fat, a strengthening of muscles, tendons and bones, an improvement of blood lipid profile, and a better balance between oxygen demand and supply in the myocardium. The preventive value of such changes is often seen in measures of perceived health or their practical consequences. Industrial fitness programmes apparently reduce the use of medical services (physician visits and hospital days), with gains of productivity, a lessening of absenteeism, and a lower employee turnover. Techniques such as the Canadian Health Hazard Appraisal questionnaire suggest a general reduction in 'risk-taking' behaviour among exercise-class participants, with a substantial reduction in their 'appraised' age. There is little evidence that regular moderate exercise can alter the response to acute disease, but both theoretical considerations and epidemiological data suggest the value of physical activity in preventing manifestations of ischaemic heart disease, obesity and maturity onset diabetes, cholecystitis, hypertension, certain neuroses, and age-related pathologies. A fit individual is also at a lesser risk of industrial injury, and is capable of living independently for a longer fraction of his or her old age. It is concluded that physical activity is one of the more useful tactics of preventive medicine; the current challenge to both research workers and policy makers is to carry this message beyond the white-collar executive to such target groups as blue-collar workers, ethnic minorities, housewives, the elderly and the handicapped.
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PMID:The value of physical fitness in preventive medicine. 384 82


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