Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0028738 (nystagmus)
7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Eight monkeys were treated with 65 X 150 mg/kg Streptomycine-Sulfate per day given intramuscularly. Their vestibular reactions were investigated several times during and after (up to 7 1/2 months) the medication. Using nystagmography, a decrease of excitability could be realized as long as the drug was given. After the stop of the injections the excitability returned, mostly even up to the normal level. The most reliable vestibular reactions were the vestibular threshold, respectively duration and frequency of the postrotatory nystagmus. Additional medicaiton of Ozothin had some influence on the toxicity of Streptomycine towards the auditory system, but no effect at all regarding the vestibular reactions.
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PMID:[Inner-ear of monkeys under the influence of streptomycin-sulfate (author's transl)]. 81 87