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Query: UMLS:C0028738 (nystagmus)
 7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Positional nystagmus and body sway were measured for 8 hours following alcohol ingestion in 27 human volunteers. The intensity of positional alcohol nystagmus phase I (PAN-I) correlated well with blood alcohol concentration (BAC) along the time axis; the correlation coefficient between PAN-I and BAC 1 hour after alcohol ingestion was 0.62 (P less than .01). The minimum threshold BAC resulting in PAN-I was 0.23 mg/mL. Body sway was measured by stabilometry. The circumscribed area of posturography before and after alcohol ingestion was compared. Temporal changes in body sway and BAC were also closely correlated. The BAC threshold for increased body sway was estimated to be somewhere between 0.5 and 0.8 mg/mL, considerably higher than the threshold for PAN-I. Measurements of blood acetaldehyde, the dehydrated product of ethanol metabolism, showed no correlation with either the intensity of PAN or changes in body sway. The intensity of PAN and body sway measured at the time of peak BAC 1 hour after alcohol ingestion, however, showed significant positive correlation (r = .50, n = 25; P less than .01).
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PMID:Positional nystagmus and body sway after alcohol ingestion. 228 44

Movements of the centre of gravity during 60 s of standing with eyes closed and eyes open were analysed before and after alcohol ingestion up to 8 h in 37 healthy human subjects. Blood alcohol and acetaldehyde concentrations (BAC and BAcHC) were measured simultaneously. Among the parameters analysed, area of posturogram was the most sensitive indicator; it increased to 3.8 times that of the control value at 60 min, after 3.5 ml/kg of ingested whisky (mean BAC of this group was 1.4 mg/ml), with the eyes open. The Romberg ratio, which denotes eyes closed relative to eyes open, remained constant. By contrast, there was little change in stabilometry in cases of 1.2 ml/kg of whisky ingestion (mean BAC at 60 min was 0.58 mg/ml). It is considered that body sway starts to increase when the BAC level exceeds 0.6 mg/ml on average; this value is only higher than the threshold of positional alcohol nystagmus. Correlation coefficients between BAC and each parameter of the stabilogram in the eyes open condition, such as area, X- and Y-axis diameters, and velocity of body sway, were 0.53, 0.45 and 0.48, respectively (p less than 0.01). There was no positive correlation between BAcHC and these parameters.
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PMID:Analysis of body sway pattern after alcohol ingestion in human subjects. 263 13

The aim of this paper is to present a case of acute occupational mercury poisoning treated at the Clinical Department of Occupational Diseases. A welder, forty years old was employed at a large chemical plant in the dissembling department involved in the production of acetaldehyde. The patient was referred to the hospital by an occupational physician. During his shift; dissembling mercury-covered tubes a nausea, abdominal pain and elevated temperature occurred. He was also complaining of headache and symptoms of gingivitis, which lasted two weeks before hospitalization. Before admission to the Clinical Department, mercury concentrations in urine were measured twice. The urine mercury levels were very high, impossible to determine precisely. During hospitalization, the patient was complaining of head and gingiva pains. Since the symptoms persisted and high urine mercury levels (830 micrograms/l) were determined--DMPS--Heyl was administered. After treatment symptoms subsided and the concentration of mercury in urine was gradually returning to normal. The results of laboratory tests did not reveal any impairment of internal organs. Consultant in neurology found the presence of nystagmus and positive Romberg test in the patient. Neurological signs disappeared after a month. The measurements performed by the Department of Work Safety revealed high exceeded hygiene permissible limits of mercury vapors in the air. The information provided by the employer's technical services also showed that the patient was working with the face mask, but its absorber was not readjusted to mercury vapors. A control ambulatory examination (one and a half year later) did not reveal health effects of acute exposure to mercury vapors.
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PMID:[Occupational acute mercury intoxication--a case report]. 1247 11