Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028738 (nystagmus)
 7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 52-year-old woman who had been treated with lithium carbonate for 10 years developed a downbeat nystagmus. The literature describes downbeat nystagmus as a rare side-effect of lithium carbonate. In this patient other causes of downbeat nystagmus were ruled out. In most cases stopping lithium carbonate does not alleviate the symptoms, which are often debilitating. At the moment there is no adequate treatment for the condition. In some cases, however, the symptoms subside after the patient stops taking lithium. Therefore, we consider that early recognition of downbeat nystagmus in patients being treated with lithium carbonate is vitally important.
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PMID:[Downbeat nystagmus - a rare side-effect of lithium carbonate]. 2560 29

We report a case of lithium-induced downbeat nystagmus and horizontal gaze palsy in a 62-year-old woman who was treated for a bipolar affective disorder with lithium carbonate for one month. At presentation serum lithium was within therapeutic range. No alternative causes of the ocular motility disturbances were found, and the patient improved significantly as lithium carbonate was discontinued.
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PMID:Lithium-Induced Downbeat Nystagmus and Horizontal Gaze Palsy. 2734 48

We report the case of a 76-year old lady under lithium carbonate for a bipolar disorder who presented with a suspected optic neuritis. A typical lithium-induced downbeat nystagmus was observed. Discontinuation of lithium therapy resulted in frank improvement in visual acuity and disappearance of the nystagmus.
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PMID:Lithium-induced downbeat nystagmus. 2926 83


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