Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028738 (nystagmus)
 7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The inside of an epidermoid is formed by masses of epithelial debris, desquamative keratin and cells derived from the epithelial capsule which accumulate very slowly within the capsule. As a result, the growth of the tumor is very slow, and the clinical signs are very diverse and bizarre because of the situation and extension of the epidermoids throughout the basal cisterns. A 52-year-old housewife was admitted to our clinic with complaints of dizziness and gait disturbance. The abnormal neurological findings were truncal ataxia, lt-trigeminal disturbance, lt-facial palsy, lt-hearing disturbance, lt-cerebellar signs (dysmetria, dysdiadochokinesia) and nystagmus. CT scan revealed low density area in the prepontine cistern and lt-cerebello-pontine angle, which was not enhanced following intravenous injection of the contrast medium. Metrizamide CT cisternography showed staining of the tumor heterogeneously revealing a honeycomb appearance. MRI showed the tumor clearly as well as the severe atrophy of the lt-cerebellar hemisphere and the pontine basal area. In this case atrophy of the cerebellar hemisphere and pons may have resulted from being compressed by the tumor. Because of this, we think it necessary to stress that early diagnosis and operation of the epidermoid are very important.
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PMID:[Cerebello-pontine angle epidermoid with cerebellar atrophy; report of a case]. 281 70

Three inherited diseases of cattle seen in the past 2 years were described. Familial acantholysis of Angus cattle was seen in 9/54 calves born to cows inadvertently mated to a full sibling bull. Sloughing skin from the joints, nose and palate were seen at 1 day of age, confirmed as suprabasilar clefts on histopathology. A 2-year-old Charolais steer was noted at ante-mortem slaughter inspection with a whole body tremor and nystagmus. Histopathologically, eosinophilic plaques expanded white matter throughout the brain, consistent with a syndrome of 'progressive ataxia' of Charolais cattle. Two calves born from Red Devon cattle had marked hyperkeratosis, microtia and periocular reddening with deep fissuring of the keratin, characteristic of congenital ichthyosis.
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PMID:A triad of bovine inherited diseases (abstract). 1603 97