Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028738 (nystagmus)
 7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Seventy-nine consecutive patients, 70 patients with acoustic neurinomas (ACN) and 9 patients with cerebello-pontine angle tumours of other etiology (o-CPA) were analysed with respect to tumour size and the result of the caloric and oculomotor tests. The size of the tumour was judged by the largest diameter calculated from the computerized tomography. A highly significant linear relationship between tumour size and caloric side difference was found for the group of ACN patients who had normal oculomotor function. A unilateral loss of caloric response on the tumour side was found in 75% of the ACN patients with tumours larger than 20 mm, but not in any of the ACN patients with tumours smaller than 10 mm. Oculomotor dysfunction (OMD), defined as disturbed pursuit eye movements and/or gaze nystagmus was frequently found in the patients with ACN larger than 20 mm (77%), and was present in all but one of the o-CPA patients. However, the caloric response on the tumour side was significantly more impaired in the group of ACN patients with OMD than in the o-CPA group. A combined view of the oculomotor and caloric test results offers a possibility to obtain a rough estimate of tumour size as well as to distinguish ACNs from other types of tumours in the cerebello-pontine angle.
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PMID:The relationship between caloric response, oculomotor dysfunction and size of cerebello-pontine angle tumours. 326 53

Findings of electronystagmography in 30 patients with posterior cranial fossa tumor were analysed. Of the 23 cases of CPA tumor, size varied between 0.7-5.0 cm, the ENG showed: (1) The nystagmus occurred in 83% of patients. (2) In ODT, overshoots was showed in 22% of patients. (3) ETT showed type III or IV curves in 55.6% of patients. (4) OKP test decreased in 59% of patients. (5) Caloric test showed canal paresis in 85% of the patients. (6) Abnormal visual suppression test occurred in 60% of patients. (7) Abnormal ABR was found in 89% of patients. We also found that tumor larger than 2.5 cm presented a central type nystagmus (Bruns nystagmus) and involvement of the eye movement system. The electronystagmographic changes of the tumors of cerebellum (3 cases) and brain stem (4 cases) was discussed.
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PMID:[Electronystagmographic changes in patients with posterior cranial fossa tumors]. 803 98

Vestibular symptoms have been rarely described in cerebellopontine angle epidermoid tumours. We report a case of CPA epidermoid tumour presenting with subacute onset of vestibular symptoms such as vertigo, gait ataxia, and nystagmus masquerading as acute vestibular neuritis or central vertigo. The vestibular symptoms disappeared after excision of the tumour.
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PMID:Cerebellopontine angle epidermoid tumour presenting with bilateral gaze nystagmus. 1856 37