Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0028738 (nystagmus)
 7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 38-year-old white woman developed left medical rectus myositis possibly due to an immune response to mepivacaine (Carbocaine) injected around her upper left first molar. Ten months after resolution, a recurrence of left medial restus myositis and also left lateral rectus myositis occured after the injection of chemically related lidocaine (Xylocaine) in the same area. At this time, with gaze to the left, there appeared vertical pendular nystagmus of greater amplitude in the involved eye, in the absence of systemic neurologic or posterior fossa disease. This association of vertical pendular nystagmus with chronic myositis of the medial and lateral rectus, to my knowledge, has not been previously reported.
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PMID:Vertical pendular nystagmus in chronic myositis of medial and lateral rectus. 73 96

A 64-year-old monocular man had uneventful penetrating keratoplasty in his seeing eye for aphakic bullous keratopathy and counting fingers visual acuity. One year later, standard slitlamp suture removal under topical anesthesia was not possible because of sensory nystagmus. In addition, the patient could not have general anesthesia as a consequence of severe coronary artery disease. He requested that the procedure be done with a short-acting local anesthetic agent so a patch would not be necessary. He successfully had the procedure using a peribulbar injection of 2-chloroprocaine (Nesacaine-MPF); vision and ocular motility returned 15 minutes after the surgery was completed. At subsequent examinations, the visual acuity was 20/200 and the graft was clear despite a congenital macular scar.
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PMID:Short-acting peribulbar anesthesia with 2-chloroprocaine. 1177 32