Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028738 (nystagmus)
 7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ocular dysmetria is seldom mentioned in the neurootologic literature as an electronystagmographic (ENG) abnormality. For the last two years, we found ocular dysmetria on 38 cases out of 1,879 ENG recordings. Cerebellar dysfunction was the most apparent cause in 13 out of 21 cases examined by us. The group of unilateral hypermetria showed some other ENG abnormalities like positional nystagmus, post-caloric directional preponderance, failure of fixation suppression of post-caloric nystagmus (FFS), more scattered distribution of quick phase amplitudes of post-caloric and optokinetic nystagmus on the side of hypermetria. We wonder whether this symptomatology, or at least part of it, is due to dysfunction of the flocculo-nodular lobe of the cerrebellum.
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PMID:Electronystagmographic findings in cerebellar dysfunction. 93 39

The symptoms and signs of 38 cases of congenital abnormalities of foramen magnum region have been analysed. Twenty-six cases presented dizziness and dysequilibrium, among them 16 had spontaneous nystagmus. ENG investigation was made systematically in four cases with spontaneous and gaze nystagmus. Ocular dysmetria, decreased intensity of optokinetic nystagmus, abnormal smooth pursuit movement and failure of fixation suppression were observed. Causes of the abnormalities were reviewed. The pathophysiological bases for the changes in ENG were briefly discussed.
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PMID:[Otoneurologic manifestations of congenital abnormalities of foramen magnum region]. 193 Nov 79

Ocular dysmetria in vertical eye movement was confirmed by electronystagmographic recording in 100 cases. Ocular dysmetria in spontaneous vertical ocular movement was reported in seven cases. It can be called vertical rebound nystagmus. This phenomenon was more prominent in vertical movement of the eyes returning from upward gazing to mid-position than in the movements of downward gazing. Optokinetic vertical ocular dysmetria induced by vertical optokinetic stimulation was observed in 93 cases. This phenomenon was far more prominent in upward optokinetic nystagmus than in downward optokinetic nystagmus. The pattern of optokinetic vertical ocular dysmetria was classified into the following four types: the dysrhythmic type, the overshoot type, the ataxic type and the saccadic (semi-inversive) type. The pathophysiological mechanism of horizontal ocular dysmetria should be different from the mechanism of vertical ocular dysmetria.
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PMID:Vertical ocular dysmetria--vertical rebound nystagmus and optokinetic vertical ocular dysmetria. 648 79