Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0028738 (nystagmus)
7,431 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Cysticercosis is not likely to be the first diagnosis the otologist has in mind when regarding tumors in the head and neck area. The fact that this disease may present a diagnostic and therapeutic problem is illustrated by three cases, appearing in the tongue, buccal mucosa, and midline of the neck, respectively. The local finding of a soft nontender mass, the typical calcifications in the soft tissues visible on roentgenograms, and the histopathological findings are described and illustrated. Attention is drawn to the fact that cerebral cysticercosis, which is a very grave disease, may cause tinnitus, nystagmus, and hearing disturbances.
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PMID:Cysticercosis in otolaryngology. 126 89

The pretectal syndrome occurred in 2.3% of patients personally examined over an 18-year period. The symptoms were nonspecific, but the signs (abnormal pupils in 198 patients, vertical gaze limitation in 180, disjunctive horizontal eye position in 90 and vertical in 79, lid retraction in 83, and convergence-retraction nystagmus in 71) were exquisitely localizing. The etiology, skewed by the local prevalence of cysticercosis, was hydrocephalus in 80 patients, stroke in 53, and tumor in 45. The importance of timely diagnosis was underscored by the relatively good prognosis of many patients.
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PMID:The pretectal syndrome: 206 patients. 232 Feb 46

We report the case of a Mexican man who suddenly developed severe occipital headache, vomiting, vertigo, and ataxia. Neurologic examination showed nystagmus and cerebellar findings. Computed tomography of the brain demonstrated a large left cerebellar cystic lesion consistent with the diagnosis of cysticercosis. The patient was treated with dexamethasone and praziquantel and required surgical removal of the lesion to prevent herniation. He recovered without neurologic sequelae. The abrupt onset of cerebellar findings is an unusual presentation of this disease. Central nervous system cysticercosis is being recognized with increasing frequency in the United States, where it is found primarily in Hispanic and Asian immigrants. The literature of central nervous system cysticercosis is reviewed and the pathogenesis, clinical presentation, and therapy are discussed.
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PMID:Central nervous system cysticercosis simulating an acute cerebellar hemorrhage. 372 11

Fifty-six patients with cysticercosis and neuro-ophthalmic signs were examined by me during an 11-year period. Their symptoms generally reflected increased intracranial pressure caused by hydrocephalus, subacute meningitis, cerebral masses or a combination of these effects. Papilledema (37 patients) was the commonest sign, with pupillary abnormalities (16 patients) and nystagmus (12 patients) frequently encountered. Cysticercosis is a relatively benign, although episodic, disease, as long as secondary obstructive hydrocephalus is promptly diagnosed and treated by CSF shunting procedures.
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PMID:Neuro-ophthalmologic signs and symptoms of cysticercosis. 711 71

Papilledema and pretectal signs are the usual neuro-ophthalmological manifestations of cysticercosis. The following patients with severe posterior fossa involvement exhibited uncommon signs of bilateral fourth nerve palsy, facial myokymia, upbeat nystagmus, periodic alternating nystagmus, and rhythmic oculopalatal myoclonus.
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PMID:Cysticercosis: unusual neuro-ophthalmologic signs. 810 46

Cysticercosis is an infestation by Cysticercus cellulosae, the larval form of the cestode Taenia solium. C. cellulosae is preferentially encysted in the brain, striated muscles, and subcutaneous tissue. Seizures, hydrocephalus, meningitis, and focal symptoms caused by large cysts are the principal manifestations. Neuroophthalmologic signs are common with the meningitic and hydrocephalic manifestations of the disease. The first ophthalmologic clues of cysticercosis are typically papilloedema, pupillary abnormalities, or nystagmus. We report an atypical presentation of neurocysticercosis in two patients, with chief complaints of vertical diplopia and nystagmus.
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PMID:Atypical ophthalmological presentation of neurocysticercosis in two children. 1764 40