Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027960 (mole)
21,279 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The title compounds have been synthesized in good yields by the interaction of 2,3,4-pentanetrione-3-oxime with ethanedithioamide in 1:1, 1:2, and 2:2 mole proportions. The structures of these compounds have been elucidated from its physico-chemical and spectral data and by correlation with well-known products. Preliminary screening of these compounds for biological activity against several microorganisms has indicated that they are selective growth inhibitors of Mycobacterium tuberculosis in particular.
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PMID:Synthesis, structural characterization and antimicrobial studies of 2,4-pentanedione derivatives. Part I. 967 54