Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027960 (mole)
 21,279 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Pyridoxal phosphate N-oxide and 2'-hydroxypyridoxal phosphate served as the coenzyme for aspartate beta-decarboxylase (EC 4.1.1.12) from Pseudomonas dacunhae. Reconstituted enzymes with those pyridoxal phosphate analogues exhibited an absorption band near 370 nm. Close to 1 mole of vitamin B6 derivative is bound per minimal catalytic unit with high affinity. The decarboxylase, desulfinase, and transaminase activites of the both pyridoxal phosphate derivate-enzymes are relatively low. But the Km values for aspartate and cysteine sulfinate are not affected.
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PMID:Effects of pyridoxal phosphate N-oxide and 2'-hydroxy pyridoxal phosphate on L-aspartate beta-decarboxylase. 116 62