Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027947 (neutropenia)
17,527 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
granulocyte colony-stimulating factor 1329
Sep 1087
granulocyte 1003
G-CSF 630
CSF 569
cytokine 324
Pseudomonas 303
non-Hodgkin's lymphoma 269
granulocyte-macrophage colony-stimulating factor 263
She 238
GM-CSF 235
hemoglobin 225
CD4 218
interferon 202
lymphoid 189
erythroid 186
Mol 160
granulocyte colony stimulating factor 157
granulocyte-macrophage 148
CHOP 142
HLA 135
C-reactive protein 123
erythropoietin 122
HER2 122
CD8 113
X-linked 107
CD20 104
albumin 103
CD34 101
AML 99
neutrophil elastase 99
myeloperoxidase 95
epidermal growth factor receptor 94
IFN 86
topoisomerase I 82
tumor necrosis factor 82
white cell 81
Interleukin-3 79
tyrosine kinase 78
IL-6 78
macrophage colony-stimulating factor 76
Barth syndrome 76
IgA 75
alkaline phosphatase 71
NHL 67
lipopolysaccharide 67
CD11b 66
ALL 66
glycoprotein 63
TNF 60
alanine aminotransferase 59
G-CSF receptor 59
aspartate aminotransferase 58
MDS 56
IL-3 56
serum albumin 55
PEG 55
glucan 53
gut 52
UGT1A1 52
MIC 50
lactate dehydrogenase 49
megakaryocyte 48
thrombopoietin 48
glucose-6-phosphatase 47
MRI 47
B12 46
CD16 46
hormone receptor 45
SCT 45
CD18 44
interleukin-6 44
Cytokine 43
IL-1 43
IL-8 43
p53 42
GSD 41
collagen 41
interleukin-2 41
TNF-alpha 39
more...
Disease
neutropenia 17527
cancer 4082
thrombocytopenia 3338
anemia 2036
tumor 1129
leukemia 995
sepsis 979
leukopenia 972
lymphoma 874
breast cancer 818
sepsis 812
acute myeloid leukemia 766
myelosuppression 724
pneumonia 707
fungal infection 550
lung cancer 546
non-small cell lung cancer 535
myelodysplastic syndrome 502
bacteremia 482
multiple myeloma 476
metastatic breast cancer 470
agranulocytosis 451
aspergillosis 438
rash 434
lymphopenia 423
metastases 397
Hodgkin's disease 396
immunodeficiency 395
AIDS 379
colorectal cancer 376
peripheral neuropathy 370
HIV 357
carcinoma 353
infectious diseases 353
hematologic malignancies 337
non-Hodgkin's lymphoma 332
Infection 331
acute lymphoblastic leukemia 315
stomatitis 309
acute leukemia 295
aplastic anemia 269
cytomegalovirus 269
graft-versus-host disease 263
gastric cancer 259
adenocarcinoma 254
chronic lymphocytic leukemia 244
ovarian cancer 242
candidiasis 241
severe congenital neutropenia 231
rheumatoid arthritis 227
pancytopenia 225
neuropathy 224
lymphocytosis 218
lung carcinoma 212
hypertension 212
squamous cell carcinoma 209
chronic lymphocytic leukemia 193
Febrile neutropenia 179
bacterial infection 168
small cell lung cancer 163
B-cell lymphoma 159
Infections 146
lymphadenopathy 142
Leukemia 141
hemolytic anemia 140
diabetes 139
systemic lupus erythematosus 138
chronic myeloid leukemia 137
measurable disease 129
Felty's syndrome 129
hand-foot syndrome 119
prostate cancer 119
mucormycosis 118
vasculitis 113
pancreatic cancer 113
eosinophilia 113
melanoma 112
fungemia 111
depression 110
Klebsiella 105
more...
Symptom
diarrhea 1330
nausea 899
fatigue 792
vomiting 763
anorexia 345
nausea and vomiting 303
splenomegaly 229
pain 217
asthenia 182
headache 168
abdominal pain 148
myalgia 134
dyspnea 133
constipation 110
fever of unknown origin 107
arthralgia 98
cough 92
bone pain 82
seizures 77
respiratory distress 74
hepatomegaly 71
Ill 71
lethargy 69
weakness 66
chills 65
hepatosplenomegaly 60
erythema 54
hypotonia 39
paresthesia 38
decreased appetite 38
hemoptysis 33
sleepiness 28
dizziness 28
back pain 26
flushing 25
chest pain 23
anesthesia 23
ataxia 19
discomfort 19
discomfort 19
rigors 18
hypothermia 17
syncope 16
tachypnea 16
adenitis 16
insomnia 14
sore throat 13
cachexia 13
acute abdomen 13
epigastric pain 12
exhaustion 12
abdominal discomfort 11
hypoproteinemia 11
pallor 10
collapse 9
shortness of breath 9
nasal discharge 9
low back pain 8
analgesia 8
numbness 8
colic 7
tremor 7
acute abdominal pain 7
pachyonychia 7
cyanosis 7
hoarseness 7
tinnitus 6
wheezing 6
HSA 6
muscle cramps 6
night sweats 6
loss of taste 6
starvation 6
non-productive cough 5
neck pain 5
productive cough 5
right lower quadrant pain 5
abdominal cramps 5
Severe diarrhea 5
dysuria 4
more...
Drug
CSF 760
G-CSF 754
Docetaxel 261
Taxol 197
CPT-11 159
Filgrastim 155
Filgrastim 135
Irinotecan 125
Dermatol 108
Taxotere 90
CTX 90
Rituximab 83
Vinorelbine 82
TTC 64
Lenalidomide 62
Adriamycin 56
MDS 56
Oxaliplatin 47
Pemetrexed 46
Fluconazole 45
CTC 43
CTC 43
AZT 42
Etoposide 41
AZT 38
Bortezomib 38
AmBisome 35
Bevacizumab 35
ampicillin 35
IL-2 34
Ganciclovir 34
Navelbine 34
Posaconazole 34
Fludarabine 32
Caspofungin 30
GEO 28
Gemzar 28
Clopidogrel 27
Micafungin 27
ADM 26
Herceptin 26
IPM 25
Campath 25
Campath 25
Leucovorin 24
Itraconazole 24
Amifostine 24
-deoxyadenosine 22
Meropenem 22
Lenograstim 22
Meropenem 21
Piperacillin 20
Ixabepilone 18
Trabectedin 18
Cardiovasc 18
IFN-gamma 17
Asthma 16
Indomethacin 16
CTX 15
CTX 15
TAC 14
Xeloda 14
Imatinib 14
AraC 13
VCR 13
Cetuximab 13
Tocilizumab 13
Novantrone 13
PFA 12
Erlotinib 12
Prednisolone 12
Trimethoprim-sulfamethoxazole 12
Ceftazidime 12
Alimta 12
ABC 11
Everolimus 11
Monit 11
Clofarabine 11
Dasatinib 11
Cremophor EL 10
more...
Enzyme
ERK 217
alanine aminotransferase 157
peroxidase 108
aspartate aminotransferase 94
neutrophil elastase 83
focal adhesion kinase 81
alkaline phosphatase 71
lactate dehydrogenase 54
glucose-6-phosphatase 47
topoisomerase 47
topoisomerase 47
BMT 43
AST 38
thymidylate synthase 37
beta-lactamase 35
asparaginase 34
prostate-specific antigen 34
P-glycoprotein 32
MTD 30
elastase 29
CYP3A4 27
UDP-glucuronosyltransferase 27
ceruloplasmin 26
reverse transcriptase 26
catalase 24
mitogen-activated protein kinase 24
dihydropyrimidine dehydrogenase 23
CPT 22
CPT 22
CPT 22
dihydropyrimidine dehydrogenase 21
lysozyme 21
protein kinase 20
proteasome 20
superoxide dismutase 19
creatine kinase 19
caspase-1 19
dihydrofolate reductase 17
PARP 16
thrombin 15
thromboplastin 15
APC 13
thiopurine methyltransferase 13
NADPH oxidase 13
gamma-glutamyl transpeptidase 12
protein kinase C 12
adenosine deaminase 12
NADPH oxidase 12
adenosine deaminase 12
CD10 12
acid phosphatase 12
thymidine phosphorylase 11
MIP 11
RNA polymerase 11
ACE 10
lipase 10
ribonucleotide reductase 10
MDR 9
DCF 9
beta-glucuronidase 9
xanthine oxidase 9
MEK 9
carboxylesterase 9
ribonucleotide reductase 9
glutathione S-transferase 9
methylenetetrahydrofolate reductase 8
BAL 8
phosphatidylinositol 3-kinase 8
CD13 8
methylenetetrahydrofolate reductase 8
renin 8
cathepsin G 8
TdT 7
endonuclease 7
phosphodiesterase 7
DNA methyltransferase 7
transcriptase 7
DNA polymerase 7
kinesin 6
trypsin 6
more...
Compound
Clin 2014
Dec 1168
DNA 452
creatinine 238
Docetaxel 212
Paclitaxel 205
5-FU 188
CPT-11 157
Gemcitabine 146
Gemcitabine 146
oxygen 132
iron 119
glucose 110
water 110
CBDCA 108
CBDCA 108
DDP 108
PEG 97
Adriamycin 91
CTX 90
His 89
copper 88
folinic acid 88
Amphotericin B 87
sodium 81
VP-16 79
acetate 78
phosphate 68
SN-38 67
AZT 62
Topotecan 62
Topotecan 61
Ara-C 61
Clozapine 61
TNF 60
calcium 57
PEG 57
Ara-C 52
ADR 50
MIC 50
Methotrexate 47
urea 45
Optimal 44
zinc 42
nitrogen 41
Vancomycin 40
Phe 39
sulfate 39
carbonate 38
Ticlopidine 36
Capecitabine 35
leucine 34
Levamisole 33
Ifosfamide 33
methionine 32
retinoic acid 32
Epirubicin 32
GPT 31
Voriconazole 30
tyrosine 29
potassium 29
6-12 28
MTX 28
TMP 27
TMP 27
TMP 27
TMP 27
DLT 26
Dexamethasone 26
iodine 26
ABL 26
CPT 26
BCNU 25
uridine 25
arginine 25
Mitoxantrone 25
BCR 25
Neo 24
CAM 24
glucose-6-phosphate 23
more...