Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027947 (
neutropenia
)
17,527
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
granulocyte colony-stimulating factor
1329
Sep
1087
granulocyte
1003
G-CSF
630
CSF
569
cytokine
324
Pseudomonas
303
non-Hodgkin's lymphoma
269
granulocyte-macrophage colony-stimulating factor
263
She
238
GM-CSF
235
hemoglobin
225
CD4
218
interferon
202
lymphoid
189
erythroid
186
Mol
160
granulocyte colony stimulating factor
157
granulocyte-macrophage
148
CHOP
142
HLA
135
C-reactive protein
123
erythropoietin
122
HER2
122
CD8
113
X-linked
107
CD20
104
albumin
103
CD34
101
AML
99
neutrophil elastase
99
myeloperoxidase
95
epidermal growth factor receptor
94
IFN
86
topoisomerase I
82
tumor necrosis factor
82
white cell
81
Interleukin-3
79
tyrosine kinase
78
IL-6
78
macrophage colony-stimulating factor
76
Barth syndrome
76
IgA
75
alkaline phosphatase
71
NHL
67
lipopolysaccharide
67
CD11b
66
ALL
66
glycoprotein
63
TNF
60
alanine aminotransferase
59
G-CSF receptor
59
aspartate aminotransferase
58
MDS
56
IL-3
56
serum albumin
55
PEG
55
glucan
53
gut
52
UGT1A1
52
MIC
50
lactate dehydrogenase
49
megakaryocyte
48
thrombopoietin
48
glucose-6-phosphatase
47
MRI
47
B12
46
CD16
46
hormone receptor
45
SCT
45
CD18
44
interleukin-6
44
Cytokine
43
IL-1
43
IL-8
43
p53
42
GSD
41
collagen
41
interleukin-2
41
TNF-alpha
39
more...
Disease
neutropenia
17527
cancer
4082
thrombocytopenia
3338
anemia
2036
tumor
1129
leukemia
995
sepsis
979
leukopenia
972
lymphoma
874
breast cancer
818
sepsis
812
acute myeloid leukemia
766
myelosuppression
724
pneumonia
707
fungal infection
550
lung cancer
546
non-small cell lung cancer
535
myelodysplastic syndrome
502
bacteremia
482
multiple myeloma
476
metastatic breast cancer
470
agranulocytosis
451
aspergillosis
438
rash
434
lymphopenia
423
metastases
397
Hodgkin's disease
396
immunodeficiency
395
AIDS
379
colorectal cancer
376
peripheral neuropathy
370
HIV
357
carcinoma
353
infectious diseases
353
hematologic malignancies
337
non-Hodgkin's lymphoma
332
Infection
331
acute lymphoblastic leukemia
315
stomatitis
309
acute leukemia
295
aplastic anemia
269
cytomegalovirus
269
graft-versus-host disease
263
gastric cancer
259
adenocarcinoma
254
chronic lymphocytic leukemia
244
ovarian cancer
242
candidiasis
241
severe congenital neutropenia
231
rheumatoid arthritis
227
pancytopenia
225
neuropathy
224
lymphocytosis
218
lung carcinoma
212
hypertension
212
squamous cell carcinoma
209
chronic lymphocytic leukemia
193
Febrile neutropenia
179
bacterial infection
168
small cell lung cancer
163
B-cell lymphoma
159
Infections
146
lymphadenopathy
142
Leukemia
141
hemolytic anemia
140
diabetes
139
systemic lupus erythematosus
138
chronic myeloid leukemia
137
measurable disease
129
Felty's syndrome
129
hand-foot syndrome
119
prostate cancer
119
mucormycosis
118
vasculitis
113
pancreatic cancer
113
eosinophilia
113
melanoma
112
fungemia
111
depression
110
Klebsiella
105
more...
Symptom
diarrhea
1330
nausea
899
fatigue
792
vomiting
763
anorexia
345
nausea and vomiting
303
splenomegaly
229
pain
217
asthenia
182
headache
168
abdominal pain
148
myalgia
134
dyspnea
133
constipation
110
fever of unknown origin
107
arthralgia
98
cough
92
bone pain
82
seizures
77
respiratory distress
74
hepatomegaly
71
Ill
71
lethargy
69
weakness
66
chills
65
hepatosplenomegaly
60
erythema
54
hypotonia
39
paresthesia
38
decreased appetite
38
hemoptysis
33
sleepiness
28
dizziness
28
back pain
26
flushing
25
chest pain
23
anesthesia
23
ataxia
19
discomfort
19
discomfort
19
rigors
18
hypothermia
17
syncope
16
tachypnea
16
adenitis
16
insomnia
14
sore throat
13
cachexia
13
acute abdomen
13
epigastric pain
12
exhaustion
12
abdominal discomfort
11
hypoproteinemia
11
pallor
10
collapse
9
shortness of breath
9
nasal discharge
9
low back pain
8
analgesia
8
numbness
8
colic
7
tremor
7
acute abdominal pain
7
pachyonychia
7
cyanosis
7
hoarseness
7
tinnitus
6
wheezing
6
HSA
6
muscle cramps
6
night sweats
6
loss of taste
6
starvation
6
non-productive cough
5
neck pain
5
productive cough
5
right lower quadrant pain
5
abdominal cramps
5
Severe diarrhea
5
dysuria
4
more...
Drug
CSF
760
G-CSF
754
Docetaxel
261
Taxol
197
CPT-11
159
Filgrastim
155
Filgrastim
135
Irinotecan
125
Dermatol
108
Taxotere
90
CTX
90
Rituximab
83
Vinorelbine
82
TTC
64
Lenalidomide
62
Adriamycin
56
MDS
56
Oxaliplatin
47
Pemetrexed
46
Fluconazole
45
CTC
43
CTC
43
AZT
42
Etoposide
41
AZT
38
Bortezomib
38
AmBisome
35
Bevacizumab
35
ampicillin
35
IL-2
34
Ganciclovir
34
Navelbine
34
Posaconazole
34
Fludarabine
32
Caspofungin
30
GEO
28
Gemzar
28
Clopidogrel
27
Micafungin
27
ADM
26
Herceptin
26
IPM
25
Campath
25
Campath
25
Leucovorin
24
Itraconazole
24
Amifostine
24
-deoxyadenosine
22
Meropenem
22
Lenograstim
22
Meropenem
21
Piperacillin
20
Ixabepilone
18
Trabectedin
18
Cardiovasc
18
IFN-gamma
17
Asthma
16
Indomethacin
16
CTX
15
CTX
15
TAC
14
Xeloda
14
Imatinib
14
AraC
13
VCR
13
Cetuximab
13
Tocilizumab
13
Novantrone
13
PFA
12
Erlotinib
12
Prednisolone
12
Trimethoprim-sulfamethoxazole
12
Ceftazidime
12
Alimta
12
ABC
11
Everolimus
11
Monit
11
Clofarabine
11
Dasatinib
11
Cremophor EL
10
more...
Enzyme
ERK
217
alanine aminotransferase
157
peroxidase
108
aspartate aminotransferase
94
neutrophil elastase
83
focal adhesion kinase
81
alkaline phosphatase
71
lactate dehydrogenase
54
glucose-6-phosphatase
47
topoisomerase
47
topoisomerase
47
BMT
43
AST
38
thymidylate synthase
37
beta-lactamase
35
asparaginase
34
prostate-specific antigen
34
P-glycoprotein
32
MTD
30
elastase
29
CYP3A4
27
UDP-glucuronosyltransferase
27
ceruloplasmin
26
reverse transcriptase
26
catalase
24
mitogen-activated protein kinase
24
dihydropyrimidine dehydrogenase
23
CPT
22
CPT
22
CPT
22
dihydropyrimidine dehydrogenase
21
lysozyme
21
protein kinase
20
proteasome
20
superoxide dismutase
19
creatine kinase
19
caspase-1
19
dihydrofolate reductase
17
PARP
16
thrombin
15
thromboplastin
15
APC
13
thiopurine methyltransferase
13
NADPH oxidase
13
gamma-glutamyl transpeptidase
12
protein kinase C
12
adenosine deaminase
12
NADPH oxidase
12
adenosine deaminase
12
CD10
12
acid phosphatase
12
thymidine phosphorylase
11
MIP
11
RNA polymerase
11
ACE
10
lipase
10
ribonucleotide reductase
10
MDR
9
DCF
9
beta-glucuronidase
9
xanthine oxidase
9
MEK
9
carboxylesterase
9
ribonucleotide reductase
9
glutathione S-transferase
9
methylenetetrahydrofolate reductase
8
BAL
8
phosphatidylinositol 3-kinase
8
CD13
8
methylenetetrahydrofolate reductase
8
renin
8
cathepsin G
8
TdT
7
endonuclease
7
phosphodiesterase
7
DNA methyltransferase
7
transcriptase
7
DNA polymerase
7
kinesin
6
trypsin
6
more...
Compound
Clin
2014
Dec
1168
DNA
452
creatinine
238
Docetaxel
212
Paclitaxel
205
5-FU
188
CPT-11
157
Gemcitabine
146
Gemcitabine
146
oxygen
132
iron
119
glucose
110
water
110
CBDCA
108
CBDCA
108
DDP
108
PEG
97
Adriamycin
91
CTX
90
His
89
copper
88
folinic acid
88
Amphotericin B
87
sodium
81
VP-16
79
acetate
78
phosphate
68
SN-38
67
AZT
62
Topotecan
62
Topotecan
61
Ara-C
61
Clozapine
61
TNF
60
calcium
57
PEG
57
Ara-C
52
ADR
50
MIC
50
Methotrexate
47
urea
45
Optimal
44
zinc
42
nitrogen
41
Vancomycin
40
Phe
39
sulfate
39
carbonate
38
Ticlopidine
36
Capecitabine
35
leucine
34
Levamisole
33
Ifosfamide
33
methionine
32
retinoic acid
32
Epirubicin
32
GPT
31
Voriconazole
30
tyrosine
29
potassium
29
6-12
28
MTX
28
TMP
27
TMP
27
TMP
27
TMP
27
DLT
26
Dexamethasone
26
iodine
26
ABL
26
CPT
26
BCNU
25
uridine
25
arginine
25
Mitoxantrone
25
BCR
25
Neo
24
CAM
24
glucose-6-phosphate
23
more...