Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027947 (neutropenia)
17,527 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
granulocyte colony-stimulating factor 1329
Sep 1087
granulocyte 1003
G-CSF 630
CSF 569
cytokine 324
Pseudomonas 303
non-Hodgkin's lymphoma 269
granulocyte-macrophage colony-stimulating factor 263
She 238
GM-CSF 235
hemoglobin 225
CD4 218
interferon 202
lymphoid 189
erythroid 186
Mol 160
granulocyte colony stimulating factor 157
granulocyte-macrophage 148
CHOP 142
HLA 135
C-reactive protein 123
erythropoietin 122
HER2 122
CD8 113
X-linked 107
CD20 104
albumin 103
CD34 101
neutrophil elastase 99
AML 99
myeloperoxidase 95
epidermal growth factor receptor 94
IFN 86
tumor necrosis factor 82
topoisomerase I 82
white cell 81
Interleukin-3 79
tyrosine kinase 78
IL-6 78
Barth syndrome 76
macrophage colony-stimulating factor 76
IgA 75
alkaline phosphatase 71
NHL 67
lipopolysaccharide 67
CD11b 66
ALL 66
glycoprotein 63
TNF 60
G-CSF receptor 59
alanine aminotransferase 59
aspartate aminotransferase 58
IL-3 56
MDS 56
serum albumin 55
PEG 55
glucan 53
UGT1A1 52
gut 52
MIC 50
lactate dehydrogenase 49
megakaryocyte 48
thrombopoietin 48
glucose-6-phosphatase 47
MRI 47
B12 46
CD16 46
hormone receptor 45
SCT 45
CD18 44
interleukin-6 44
IL-1 43
Cytokine 43
IL-8 43
p53 42
interleukin-2 41
collagen 41
GSD 41
ferritin 39
TNF-alpha 39
AST 38
hairy 38
c-fms 38
tafazzin 37
LPS 37
mTOR 37
fibrinogen 37
endoplasmic reticulum 36
nodal 36
LGL 36
B19 36
EGFR 35
interferon-alpha 35
thymidylate synthase 35
prostate-specific antigen 35
vascular endothelial growth factor 35
IL-2 34
CD56 34
histone deacetylase 34
Pol 33
TAZ 33
THC 33
chemokine 33
stem cell factor 33
LDH 33
G6PC3 32
cell surface receptor 32
CDK4 32
P-glycoprotein 32
Fas 32
proteasome inhibitor 31
glucose-6-phosphate transporter 31
HAX1 31
CD57 31
CLL 31
CXCR4 31
GPT 31
MTD 30
lactoferrin 30
osteosarcoma 30
reserved 30
insulin 30
natural killer cell 30
estrogen receptor 29
Fc gamma 29
rheumatoid factor 29
CD19 29
MTX 28
IgE 28
CD33 28
T cell receptor 27
CYP3A4 27
STAT3 27
chronic renal failure 27
TMP 27
ABL 26
rhabdomyosarcoma 26
ABCB1 25
X-linked recessive 25
BID 25
interferon-gamma 25
severe combined immunodeficiency 25
BCR 25
DLT 25
PI3K 24
interferon alpha 24
CD40 ligand 24
Granulocyte-colony stimulating factor 24
cytochrome P450 24
HLA-DR 23
dihydropyrimidine dehydrogenase 23
thymus 23
transcobalamin II 23
FAB 22
Granulocyte colony stimulating factor 22
1A1 22
TCR 22
CPT 22
ceruloplasmin 22
more...
Disease
neutropenia 17527
cancer 4082
thrombocytopenia 3338
anemia 2036
tumor 1129
leukemia 995
sepsis 979
leukopenia 972
lymphoma 874
breast cancer 818
sepsis 812
acute myeloid leukemia 766
myelosuppression 724
pneumonia 707
fungal infection 550
lung cancer 546
non-small cell lung cancer 535
myelodysplastic syndrome 502
bacteremia 482
multiple myeloma 476
metastatic breast cancer 470
agranulocytosis 451
aspergillosis 438
rash 434
lymphopenia 423
metastases 397
Hodgkin's disease 396
immunodeficiency 395
AIDS 379
colorectal cancer 376
peripheral neuropathy 370
HIV 357
infectious diseases 353
carcinoma 353
hematologic malignancies 337
non-Hodgkin's lymphoma 332
Infection 331
acute lymphoblastic leukemia 315
stomatitis 309
acute leukemia 295
cytomegalovirus 269
aplastic anemia 269
graft-versus-host disease 263
gastric cancer 259
adenocarcinoma 254
chronic lymphocytic leukemia 244
ovarian cancer 242
candidiasis 241
severe congenital neutropenia 231
rheumatoid arthritis 227
pancytopenia 225
neuropathy 224
lymphocytosis 218
hypertension 212
lung carcinoma 212
squamous cell carcinoma 209
chronic lymphocytic leukemia 193
Febrile neutropenia 179
bacterial infection 168
small cell lung cancer 163
B-cell lymphoma 159
Infections 146
lymphadenopathy 142
Leukemia 141
hemolytic anemia 140
diabetes 139
systemic lupus erythematosus 138
chronic myeloid leukemia 137
measurable disease 129
Felty's syndrome 129
hand-foot syndrome 119
prostate cancer 119
mucormycosis 118
pancreatic cancer 113
vasculitis 113
eosinophilia 113
melanoma 112
fungemia 111
depression 110
epithelial ovarian cancer 105
Klebsiella 105
sarcoma 103
LGL leukemia 100
renal failure 100
SDS 98
hypogammaglobulinemia 95
influenza 94
follicular lymphoma 93
esophagitis 93
sensory neuropathy 88
glycogen storage disease 88
opportunistic infection 88
meningitis 86
dysplasia 85
arthritis 85
virus infection 84
head and neck cancer 82
heart failure 82
hepatitis 79
proteinuria 79
colon cancer 79
enterocolitis 78
residual disease 77
myopathy 77
Barth syndrome 75
autoimmune hemolytic anemia 74
tumor progression 73
liver metastases 73
congestive heart failure 72
PCP 71
cellulitis 70
cardiomyopathy 69
glioma 69
NHL 68
renal impairment 68
lupus 68
mantle cell lymphoma 67
Epstein 66
hepatitis C 65
thrombocytosis 65
hairy cell leukemia 65
cirrhosis 64
colitis 64
tuberculosis 64
autoimmune disease 63
solid tumor 63
stroke 62
interstitial pneumonia 62
hypoglycemia 61
zygomycosis 60
peritonitis 60
esophageal cancer 60
esophageal cancer 59
chronic hepatitis 59
urinary tract infection 59
primary tumor 58
endocarditis 58
respiratory failure 57
dermatitis 57
Kaposi's sarcoma 57
cystic fibrosis 56
parvovirus 56
MDS 56
hyperglycemia 56
malnutrition 56
pancreatic insufficiency 55
sinusitis 54
T-cell lymphoma 54
dehydration 54
viremia 53
childhood cancer 53
cervical cancer 53
ischemia 52
lymphoproliferative disorders 52
idiopathic thrombocytopenic purpura 52
myocardial infarction 50
renal disease 50
lupus 49
pruritus 49
osteomyelitis 49
more...
Symptom
diarrhea 1330
nausea 899
fatigue 792
vomiting 763
anorexia 345
nausea and vomiting 303
splenomegaly 229
pain 217
asthenia 182
headache 168
abdominal pain 148
myalgia 134
dyspnea 133
constipation 110
fever of unknown origin 107
arthralgia 98
cough 92
bone pain 82
seizures 77
respiratory distress 74
Ill 71
hepatomegaly 71
lethargy 69
weakness 66
chills 65
hepatosplenomegaly 60
erythema 54
hypotonia 39
decreased appetite 38
paresthesia 38
hemoptysis 33
sleepiness 28
dizziness 28
back pain 26
flushing 25
anesthesia 23
chest pain 23
ataxia 19
discomfort 19
discomfort 19
rigors 18
hypothermia 17
syncope 16
adenitis 16
tachypnea 16
insomnia 14
sore throat 13
cachexia 13
acute abdomen 13
epigastric pain 12
exhaustion 12
abdominal discomfort 11
hypoproteinemia 11
pallor 10
collapse 9
nasal discharge 9
shortness of breath 9
numbness 8
analgesia 8
low back pain 8
pachyonychia 7
acute abdominal pain 7
colic 7
cyanosis 7
hoarseness 7
tremor 7
muscle cramps 6
HSA 6
wheezing 6
tinnitus 6
night sweats 6
loss of taste 6
starvation 6
productive cough 5
non-productive cough 5
right lower quadrant pain 5
neck pain 5
abdominal cramps 5
Severe diarrhea 5
blurred vision 4
facial pain 4
paresis 4
heartburn 4
Flu-like symptoms 4
vertigo 4
dry skin 4
thinning 4
cerebellar ataxia 4
functional recovery 4
oliguria 4
dysarthria 4
dystonia 4
angina 4
dysuria 4
emaciation 3
tingling 3
anal pain 3
periorbital edema 3
hyperoxia 3
rales 3
lightheadedness 3
spasticity 3
leg cramps 3
labored breathing 3
agitation 3
apathy 3
sneezing 3
overweight 3
generalized abdominal pain 3
exertional dyspnea 3
hypertonia 3
mouth pain 3
stridor 3
otalgia 2
pelvic pain 2
ataxic gait 2
Physical findings 2
flank pain 2
Wind 2
meningism 2
polyuria 2
generalized erythema 2
generalized rash 2
hemiplegia 2
dry eye 2
chest tightness 2
livedo 2
GI irritation 2
Reticulocytosis 2
shoulder pain 2
consciousness disturbance 2
ENT 2
dark urine 2
neuralgia 2
thigh pain 2
myoclonus 2
epigastric distress 2
urinary frequency 2
leg edema 2
Gastrointestinal symptoms 2
spasm 2
physical appearance 2
hot flashes 2
neck stiffness 2
cancer pain 2
rhinorrhea 2
body pain 2
acute stress 1
ophthalmoplegia 1
bitter taste 1
testicular pain 1
right upper quadrant pain 1
dental pain 1
abnormal gait 1
tonic-clonic seizure 1
memory loss 1
adipsia 1
presyncope 1
disturbed balance 1
ketonuria 1
more...
Drug
CSF 760
G-CSF 754
Docetaxel 261
Taxol 197
CPT-11 159
Filgrastim 155
Filgrastim 135
Irinotecan 125
Dermatol 108
Taxotere 90
CTX 90
Rituximab 83
Vinorelbine 82
TTC 64
Lenalidomide 62
MDS 56
Adriamycin 56
Oxaliplatin 47
Pemetrexed 46
Fluconazole 45
CTC 43
CTC 43
AZT 42
Etoposide 41
AZT 38
Bortezomib 38
ampicillin 35
Bevacizumab 35
AmBisome 35
Posaconazole 34
Ganciclovir 34
Navelbine 34
IL-2 34
Fludarabine 32
Caspofungin 30
Gemzar 28
GEO 28
Clopidogrel 27
Micafungin 27
ADM 26
Herceptin 26
Campath 25
Campath 25
IPM 25
Amifostine 24
Itraconazole 24
Leucovorin 24
-deoxyadenosine 22
Meropenem 22
Lenograstim 22
Meropenem 21
Piperacillin 20
Ixabepilone 18
Cardiovasc 18
Trabectedin 18
IFN-gamma 17
Indomethacin 16
Asthma 16
CTX 15
CTX 15
Imatinib 14
TAC 14
Xeloda 14
Novantrone 13
Tocilizumab 13
AraC 13
VCR 13
Cetuximab 13
Trimethoprim-sulfamethoxazole 12
Erlotinib 12
Alimta 12
Ceftazidime 12
PFA 12
Prednisolone 12
Dasatinib 11
ABC 11
Everolimus 11
Clofarabine 11
Monit 11
Cremophor EL 10
IL-11 10
Prednisone 10
Paraplatin 10
Captopril 10
Leukine 9
Idarubicin 9
Valganciclovir 9
Gleevec 8
ROC 8
Nephron 8
ascorbate 8
Tacrolimus 8
EPI 8
vitamin E 8
Anidulafungin 8
Nephron 8
anti-CD33 8
Gefitinib 7
Dial 7
Acyclovir 7
Leaf 6
Trib 6
ROS 6
ARA-C 6
MAP 6
PCP 6
Spectrum 6
DM1 6
TAK 6
Fotemustine 6
MRC 6
Sorafenib 6
Revlimid 6
Biopolymers 5
Epidoxorubicin 5
Tipifarnib 5
Gel 5
Ambisome 5
NBT 5
lysine 5
Vindesine 5
Albumin 5
Cimetidine 5
Vorinostat 5
Nelarabine 5
VCR 5
Cimetidine 5
Mutagen 5
Vindesine 5
Cidofovir 4
Histamine 4
Bayer 4
Ethyol 4
Deferasirox 4
Alliance 4
DMAP 4
ADR 4
Epoetin 4
Bactrim 4
Teniposide 4
Nafcillin 4
ENT 4
Midostaurin 4
DEX 4
Aprepitant 4
Tarceva 4
Fraction 3
Mycophenolic acid 3
Heme 3
Pixantrone 3
niacin 3
Ketoconazole 3
Moxifloxacin 3
Pertuzumab 3
Mitomycin-C 3
PMPA 3
uPA 3
Pirarubicin 3
Nartograstim 3
PMEA 3
more...
Enzyme
ERK 217
alanine aminotransferase 157
peroxidase 108
aspartate aminotransferase 94
neutrophil elastase 83
focal adhesion kinase 81
alkaline phosphatase 71
lactate dehydrogenase 54
topoisomerase 47
glucose-6-phosphatase 47
topoisomerase 47
BMT 43
AST 38
thymidylate synthase 37
beta-lactamase 35
prostate-specific antigen 34
asparaginase 34
P-glycoprotein 32
MTD 30
elastase 29
UDP-glucuronosyltransferase 27
CYP3A4 27
ceruloplasmin 26
reverse transcriptase 26
mitogen-activated protein kinase 24
catalase 24
dihydropyrimidine dehydrogenase 23
CPT 22
CPT 22
CPT 22
dihydropyrimidine dehydrogenase 21
lysozyme 21
protein kinase 20
proteasome 20
creatine kinase 19
caspase-1 19
superoxide dismutase 19
dihydrofolate reductase 17
PARP 16
thromboplastin 15
thrombin 15
APC 13
NADPH oxidase 13
thiopurine methyltransferase 13
CD10 12
adenosine deaminase 12
gamma-glutamyl transpeptidase 12
NADPH oxidase 12
protein kinase C 12
acid phosphatase 12
adenosine deaminase 12
MIP 11
thymidine phosphorylase 11
RNA polymerase 11
lipase 10
ribonucleotide reductase 10
ACE 10
MDR 9
xanthine oxidase 9
DCF 9
ribonucleotide reductase 9
beta-glucuronidase 9
MEK 9
glutathione S-transferase 9
carboxylesterase 9
CD13 8
BAL 8
renin 8
methylenetetrahydrofolate reductase 8
cathepsin G 8
phosphatidylinositol 3-kinase 8
methylenetetrahydrofolate reductase 8
TdT 7
DNA methyltransferase 7
transcriptase 7
DNA polymerase 7
endonuclease 7
phosphodiesterase 7
aldehyde dehydrogenase 6
cdc2 6
trypsin 6
kinesin 6
urokinase-type plasminogen activator 6
granzyme B 6
calcineurin 6
PCP 6
NOS 6
matrix metalloproteinase 9 5
lipoxygenase 5
kallikrein 5
acetylcholinesterase 5
caspase-3 5
phosphoinositide 3-kinase 5
purine nucleoside phosphorylase 5
MAP 4
glyceraldehyde-3-phosphate dehydrogenase 4
exoribonuclease 4
luciferase 4
Alternating 4
phospholipase C 4
DHAD 4
thyroid peroxidase 4
DNA ligase 3
DNA ligase 3
cytidine deaminase 3
S-adenosylmethionine decarboxylase 3
NO synthase 3
C3 convertase 3
polo-like kinase 1 3
ATPase 3
DNase 3
tryptase 3
p100 3
tyrosinase 3
PTA 3
CEP 3
furin 3
deoxycytidine kinase 3
factor C 3
prostate-specific membrane antigen 3
farnesyltransferase 3
PAL 3
CEP 3
AOR 3
beta-galactosidase 3
farnesyltransferase 3
cholinesterase 3
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
aldehyde dehydrogenase 2
IKK 2
hexokinase 2
alcohol oxidase 2
cytochrome oxidase 2
aldehyde dehydrogenase 2
hypoxanthine-guanine phosphoribosyltransferase 2
C3 convertase 2
monoamine oxidase 2
collagenase 2
glutathione reductase 2
glucose-6-phosphate dehydrogenase 2
CPM 2
GSK 2
callose synthase 2
glucocerebrosidase 2
folylpolyglutamate synthetase 2
STK4 2
ACS 2
plasmin 2
neuraminidase 2
glutathione synthetase 2
urease 2
proteinase-3 2
flavin-containing monooxygenase 2
caspase-8 2
urease 2
DAT 2
fumarase 2
CPN 1
nicotinamide phosphoribosyltransferase 1
more...
Compound
Clin 2014
Dec 1168
DNA 452
creatinine 238
Docetaxel 212
Paclitaxel 205
5-FU 188
CPT-11 157
Gemcitabine 146
Gemcitabine 146
oxygen 132
iron 119
glucose 110
water 110
DDP 108
CBDCA 108
CBDCA 108
PEG 97
Adriamycin 91
CTX 90
His 89
copper 88
folinic acid 88
Amphotericin B 87
sodium 81
VP-16 79
acetate 78
phosphate 68
SN-38 67
Topotecan 62
AZT 62
Ara-C 61
Topotecan 61
Clozapine 61
TNF 60
PEG 57
calcium 57
Ara-C 52
MIC 50
ADR 50
Methotrexate 47
urea 45
Optimal 44
zinc 42
nitrogen 41
Vancomycin 40
sulfate 39
Phe 39
carbonate 38
Ticlopidine 36
Capecitabine 35
leucine 34
Ifosfamide 33
Levamisole 33
retinoic acid 32
methionine 32
Epirubicin 32
GPT 31
Voriconazole 30
potassium 29
tyrosine 29
6-12 28
MTX 28
TMP 27
TMP 27
TMP 27
TMP 27
ABL 26
CPT 26
iodine 26
Dexamethasone 26
DLT 26
BCR 25
arginine 25
Mitoxantrone 25
uridine 25
BCNU 25
Neo 24
CAM 24
Cardiol 23
galactose 23
CCNU 23
pyrimidine 23
Cefepime 23
pyrimidine 23
glucose-6-phosphate 23
Amifostine 22
CPT 22
Lithium 21
Mitoxantrone 21
ATP 21
L-PAM 20
L-PAM 20
Pac 20
Piperacillin 20
ADP 20
ASA 19
nitric oxide 19
EDTA 19
A 3 19
hydrogen 19
EDTA 19
Imipenem 19
CAP 18
DFS 18
Vinblastine 18
MSG 18
Hemoglobin 18
Temozolomide 18
silver 18
ethanol 18
Vincristine 17
DIC 17
ZD1694 17
TTP 16
serine 16
lysine 16
Ciprofloxacin 16
THP 15
ITP 15
THP 15
H2O2 14
Leucovorin 14
ANCA 14
cysteine 14
Hydroxyurea 14
Ceftriaxone 14
GDP 14
Wellcome 13
MMC 13
TBI 12
CO2 12
PMA 12
Prednisolone 12
Ceftazidime 12
prostacyclin 12
FK506 12
Levofloxacin 11
CAP 11
5-Aza-2'-deoxycytidine 11
Foscarnet 11
Parenteral 11
Cyclosporine 11
salt 11
Prednisone 10
Methicillin 10
SCN 10
NADP 10
A 71 10
CTAB 10
phosphorus 10
alanine 10
BAL 10
Ribavirin 10
ADP 10
ammonia 10
benzene 10
MDR 10
TOF 10
Teicoplanin 9
more...