Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027819 (
neuroblastoma
)
27,800
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mol
1950
Sep
1852
NBS
1277
MYCN
1218
caspase-3
862
p53
708
amyloid precursor protein
614
N-myc
565
rhabdomyosarcoma
512
Bcl-2
494
ATP
478
AMP
456
endoplasmic reticulum
410
olfactory
360
nerve growth factor
307
tyrosine hydroxylase
285
adenylate cyclase
281
acetylcholinesterase
270
cytokine
263
cytochrome c
256
ERK1
254
osteosarcoma
249
prion
248
ERK
245
insulin
242
prion protein
238
MAPK
236
PrP
234
glycoprotein
233
GTP
224
proteasome
223
axonal
219
GSH
218
tyrosine kinase
216
PI3K
213
polypeptide
212
p38
207
p21
202
ubiquitin
200
opioid receptor
195
ROS
189
NMR
189
fused
187
all-trans
186
mTOR
183
lactate dehydrogenase
181
superoxide dismutase
179
caspase-9
177
brain-derived neurotrophic factor
176
bradykinin
173
AKT
172
muscarinic receptor
171
neuron-specific enolase
163
histone
161
amyloid beta
160
caspase-8
158
SDS
157
tumor necrosis factor
157
tau protein
157
interferon
153
MPP
153
PARP
150
LAN
149
JNK
147
phosphatase
146
ALK
145
MYC
143
synuclein
140
PKC
139
neurotrophin
138
ATPase
136
calmodulin
134
TNF
134
adenylyl cyclase
129
catalase
129
collagen
128
proto-oncogene
128
membrane-bound
127
ADP
125
extracellular signal-regulated kinase
125
fibronectin
125
synaptophysin
125
histone deacetylase
125
MRI
120
Rho
118
vascular endothelial growth factor
117
phosphatidylinositol 3-kinase
117
MEK
116
vimentin
116
BACE1
116
APP
111
lipopolysaccharide
111
enolase
111
GSK
110
alpha-synuclein
110
c-myc
108
Gen
107
choline acetyltransferase
106
sodium channel
106
UTR
106
LDH
106
neural cell adhesion molecule
104
calpain
104
ferritin
103
c-Jun
103
somatostatin
102
glial fibrillary acidic protein
100
ACS
100
threonine
100
non-Hodgkin's lymphoma
100
IL-6
100
receptor tyrosine kinase
99
CD56
99
nitric oxide synthase
98
insulin-like growth factor
98
annexin V
98
anaplastic lymphoma kinase
98
lymphoid
97
cyclin D1
97
microtubule-associated protein
96
Sp1
96
calcium channel
95
GTPase
95
IFN
95
neuropeptide Y
94
CHP
93
AP-1
92
LC3
91
NGF
90
mitogen-activated protein
90
5-HT3 receptor
90
ras
89
phosphodiesterase
89
HEK
87
c-fos
85
lectin
85
Nrf2
84
epidermal growth factor
82
CREB
82
GAP-43
82
HLA
81
heme oxygenase-1
80
inducible nitric oxide synthase
78
Leu5
77
She
77
SMS
77
beta 1
77
bcl-2
75
MDM2
75
HT3
75
p65
75
catenin
75
Phox2b
74
IFN-gamma
73
colon carcinoma
73
STAT3
73
erythroid
72
interleukin-2
72
peroxidase
71
IGF-I
71
more...
Disease
neuroblastoma
27800
tumor
5855
cancer
5814
Neuroblastoma
2227
Neuroblastoma
2227
Alzheimer's disease
1740
glioma
1346
NBS
1277
Parkinson's disease
867
metastases
854
melanoma
624
tumor growth
605
carcinoma
577
WT1
556
leukemia
541
rhabdomyosarcoma
509
solid tumor
501
tumorigenesis
487
lymphoma
481
Ewing's sarcoma
452
childhood cancer
451
pheochromocytoma
427
glioblastoma
360
primary tumor
352
breast cancer
348
retinoblastoma
340
sarcoma
324
tumor progression
301
osteosarcoma
290
pertussis
276
medulloblastoma
274
astrocytoma
267
ganglioneuroma
263
Hodgkin's disease
226
hepatocellular carcinoma
222
GSH
218
adenocarcinoma
208
metastatic neuroblastoma
201
acute lymphoblastic leukemia
198
lung cancer
180
dementia
176
metastatic neuroblastoma
163
scrapie
163
ischemia
157
SDS
157
lung carcinoma
151
primitive neuroectodermal tumor
149
amyotrophic lateral sclerosis
146
aggressiveness
139
stroke
139
prostate cancer
138
herpes simplex
134
hepatoblastoma
130
MCF
130
acute myeloid leukemia
130
primitive neuroectodermal tumor
129
teratoma
126
multiple myeloma
124
hypertension
121
renal cell carcinoma
121
non-Hodgkin's lymphoma
119
depression
118
rabies
114
carcinogenesis
114
cholera
109
minimal residual disease
107
plaque
107
esthesioneuroblastoma
107
HIV
105
squamous cell carcinoma
101
diabetes
100
PNET
98
residual disease
95
cognitive impairment
94
schizophrenia
90
virus infection
89
schwannoma
89
brain tumor
86
Huntington's disease
85
encephalitis
85
colorectal cancer
81
cold
80
colon cancer
79
neuropathy
79
immunodeficiency
77
SMS
77
parkinsonism
77
ovarian cancer
76
paraganglioma
75
cerebral ischemia
74
carcinoid
73
ATM
72
small cell lung cancer
71
pediatric solid tumor
69
embryonal tumor
68
bone metastases
67
thrombocytopenia
64
meningioma
63
oligodendroglioma
62
SCID
60
encephalopathy
60
anemia
59
non-small cell lung cancer
58
acute promyelocytic leukemia
57
acute leukemia
56
Burkitt's lymphoma
55
Wright
55
medullary thyroid carcinoma
54
infectious diseases
54
glioblastoma multiforme
53
liver metastases
53
peripheral primitive neuroectodermal tumor
52
cytomegalovirus
52
epilepsy
52
fibrosarcoma
51
myelosuppression
50
ependymoma
50
epithelial ovarian cancer
50
West
48
Evans
48
neurological disease
47
gastric cancer
47
Infection
47
chronic myeloid leukemia
46
Japanese encephalitis
46
aggression
45
pancreatic cancer
44
B-cell lymphoma
44
obesity
43
sepsis
43
bipolar disorder
42
hemangioma
42
embryonal carcinoma
41
Down syndrome
41
HCG
41
adenoma
41
bone marrow metastases
40
Langerhans cell histiocytosis
40
MRT
40
multiple sclerosis
39
Blocking
38
cervical cancer
38
CNS tumors
37
tumor angiogenesis
37
Creutzfeldt-Jakob disease
37
graft-versus-host disease
37
Beckwith-Wiedemann syndrome
36
PNET
36
recurrent neuroblastoma
35
sepsis
35
mental retardation
35
Horner's syndrome
35
adrenocortical carcinoma
35
neutropenia
35
measles
34
chondrosarcoma
34
mental retardation
34
neuroendocrine tumor
33
embryonal rhabdomyosarcoma
33
neurofibroma
33
more...
Symptom
pain
185
ataxia
105
myoclonus
103
starvation
75
seizures
72
collapse
62
anesthesia
50
vomiting
46
hepatomegaly
44
headache
44
diarrhea
43
analgesia
37
respiratory distress
35
weakness
34
nausea
28
abdominal pain
24
functional recovery
24
hypothermia
22
bone pain
22
cerebellar ataxia
19
memory loss
18
nausea and vomiting
18
dystonia
17
tremor
16
anosmia
15
back pain
14
dyspnea
14
hypotonia
13
discomfort
13
discomfort
13
exhaustion
12
fatigue
11
cough
11
fasciculation
10
anorexia
10
insomnia
9
rhinorrhea
9
pallor
9
hepatosplenomegaly
9
constipation
9
arthralgia
8
agitation
8
facial pain
8
lethargy
7
ENT
7
hyperoxia
7
chest pain
7
splenomegaly
7
HSA
6
bradykinesia
6
paresthesia
6
stridor
6
sleepiness
6
flushing
5
erythema
5
numbness
5
thinning
5
dizziness
5
tachypnea
4
myalgia
4
polyuria
4
hemoptysis
4
acidity
4
cachexia
4
polydipsia
4
nasal congestion
4
nasal discharge
4
cyanosis
4
DNA marker
4
neurological disability
4
paresis
4
bitter taste
4
Fluctuation
4
urinary frequency
3
Cushingoid
3
wheezing
3
paraparesis
3
spasm
3
chorea
3
masculinization
3
Respiratory symptoms
3
incoordination
3
Cushingoid
3
low back pain
3
dysuria
3
rundown
3
torticollis
3
vertigo
2
acute abdominal pain
2
asthenia
2
flank pain
2
hypercapnia
2
acute pain
2
Neuropathic pain
2
chills
2
stigma
2
hemiplegia
2
twitching
2
adenitis
2
hip pain
2
cancer pain
2
shortness of breath
2
exertional dyspnea
2
chronic constipation
2
ophthalmoplegia
2
dysarthria
2
syncope
2
acute stress
2
productive cough
2
Ill
2
hypoproteinemia
2
tonic-clonic seizure
2
spasticity
2
Spots
1
Mills
1
retching
1
Halo
1
loin pain
1
Severe diarrhea
1
sore throat
1
regurgitation
1
Hudson
1
periorbital edema
1
Opposition
1
General symptoms
1
prostration
1
shoulder pain
1
arm weakness
1
tingling
1
Bloody nipple discharge
1
distraction
1
Cullen's sign
1
eds
1
Bryant's sign
1
overweight
1
hyperemesis gravidarum
1
partial seizure
1
Scratch
1
delayed language development
1
Paroxysmal hypertension
1
acute abdomen
1
neck pain
1
orthopnea
1
sneezing
1
monoplegia
1
Blanching
1
persistent cough
1
Welt
1
apathy
1
stomach pain
1
Bryant's sign
1
general problem
1
oliguria
1
Psychiatric symptoms
1
skin irritant
1
drooling
1
body pain
1
intestinal bleeding
1
intention tremor
1
otalgia
1
more...
Drug
ROS
189
Retinoic acid
137
lysine
131
CSF
81
IFN-gamma
71
ascorbate
68
IL-2
67
Ethanol
62
MAP
58
caffeine
53
Gel
51
CTX
47
vitamin E
45
p75
40
Parkin
38
Parkin
38
ICI
36
Adriamycin
32
G-CSF
30
R-gene
30
Dermatol
30
NADH
30
KAN
29
Forskolin
28
Spectrum
26
Nephron
26
DNase I
25
TTC
24
Glutathione
23
CPT-11
22
Asn
22
ABC
22
Etoposide
21
Taxol
18
ENT
18
CAM
18
CTX
18
CTX
18
Cardiovasc
17
BoNT/A
16
THF
16
9-THC
15
CoCl2
15
VCR
15
Arsenic trioxide
15
HCH
15
CoCl2
15
Lovastatin
15
Isotretinoin
14
VCR
14
Monit
14
EPA
13
ADM
13
Bortezomib
13
ETS
13
Leaf
13
Mutagen
12
Vitamin E
12
NLF
12
NAG
12
G418
12
Heme
12
NVP
12
EE2
11
Portal
11
lactose
11
ETA
11
Sodium nitroprusside
11
BH4
11
Bupivacaine
10
Rasagiline
10
DFP
10
-deoxyadenosine
10
IFN-beta
10
uPA
10
MRC
10
citric acid
9
Angiotensin II
9
Atropine
9
ID2
9
Activin
9
Albumin
9
Estrogens
9
L-tyrosine
9
Irinotecan
8
Imatinib
8
TAT
8
CaCl2
8
CaCl2
8
CDP
8
Retinoic Acid
8
Vitamin A
8
CaCl2
8
Clonidine
7
TAC
7
Emodin
7
Phenytoin
7
CER
7
Emodin
7
Capsicum
7
Nitric Oxide
7
Gleevec
7
pyridoxal phosphate
7
Sorafenib
7
Alanine
7
AMC
6
ALA
6
Ouabain
6
Pravastatin
6
Ginseng
6
Apomorphine
6
FAD
6
Amifostine
6
NH3
6
Indomethacin
6
DHT
6
ROC
6
Rosiglitazone
6
Scopolamine
6
DHT
6
Amiloride
5
Theophylline
5
linolenate
5
Ranitidine
5
Pronase
5
Bevacizumab
5
Propofol
5
nitroglycerin
5
Simvastatin
5
RFP
5
Vorinostat
5
Donepezil
5
Cilostazol
5
Meth
5
BLM
5
ADR
5
PCP
5
Liraglutide
5
Amiloride
5
Glide
5
IL-1ra
5
CCL
5
ZnO
5
Pramipexole
4
ARA-C
4
Fentanyl
4
PTH
4
GEO
4
Prozac
4
Fluorescein
4
Zonisamide
4
Fluorescein
4
CTC
4
Vitamin B
4
Fipronil
4
CPM
4
Herceptin
4
DMSA
4
Sodium valproate
4
AraC
4
more...
Enzyme
mitogen-activated protein kinase
870
ERK
736
caspase-3
670
protein kinase
584
protein kinase C
531
luciferase
356
acetylcholinesterase
299
adenylate cyclase
282
tyrosine hydroxylase
275
proteasome
225
superoxide dismutase
224
lactate dehydrogenase
197
focal adhesion kinase
193
PARP
178
MEK
173
phospholipase C
170
catalase
167
MPP
153
ATPase
152
caspase-9
139
reverse transcriptase
128
GSK
122
complex I
122
caspase-8
121
phosphatidylinositol 3-kinase
118
enolase
113
calcineurin
110
choline acetyltransferase
109
ACS
102
trypsin
99
peroxidase
93
phosphodiesterase
91
cholinesterase
90
neuraminidase
83
monoamine oxidase
79
AMP-activated protein kinase
75
thrombin
69
glutathione peroxidase
68
P-glycoprotein
68
chloramphenicol acetyltransferase
66
CD10
65
cdc2
65
RNA polymerase
64
RNase
64
RNase
62
AMPK
62
phosphoinositide 3-kinase
61
guanylate cyclase
58
ornithine decarboxylase
55
MAP
55
glutathione S-transferase
53
succinate dehydrogenase
52
CaMKII
51
beta-secretase
48
topoisomerase
47
NO synthase
47
phospholipase A2
44
topoisomerase
44
NQO1
42
glyceraldehyde-3-phosphate dehydrogenase
42
transglutaminase
41
proteinase K
39
thymidine kinase
39
beta-galactosidase
37
alkaline phosphatase
36
NADPH oxidase
36
glyceraldehyde-3-phosphate dehydrogenase
36
NADPH oxidase
35
protein phosphatase 2A
34
caspase-1
34
glyceraldehyde-3-phosphate dehydrogenase
33
MDP
32
AMPK
31
glyceraldehyde-3-phosphate dehydrogenase
31
glyceraldehyde-3-phosphate dehydrogenase
31
phospholipase D
31
renin
30
sialidase
30
transcriptase
30
PDE
29
dopamine beta-hydroxylase
29
cytochrome oxidase
28
DNA polymerase
27
lipoxygenase
27
urokinase-type plasminogen activator
26
NOS
25
glutathione reductase
25
kinesin
24
hypoxanthine-guanine phosphoribosyltransferase
24
ribonuclease
23
ribonuclease
23
pyruvate dehydrogenase
23
cathepsin D
22
caspase-2
22
collagenase
21
tyrosinase
21
GD3 synthase
21
heme oxygenase
21
BMT
21
caspase-2
21
lipase
20
neuropathy target esterase
20
sialyltransferase
20
sialyltransferase
20
pyruvate dehydrogenase
20
pyruvate dehydrogenase
20
sialyltransferase
20
cathepsin B
20
acid phosphatase
19
GRK2
18
plasmin
17
tissue plasminogen activator
17
DNase
17
hexokinase
17
adenosine deaminase
17
adenosine deaminase
17
botulinum neurotoxin
17
demethylase
17
lysozyme
16
aconitase
16
chymotrypsin
16
PKG
16
glucose-6-phosphate dehydrogenase
15
PDK1
15
MDR
15
DNA methyltransferase
15
gamma-glutamylcysteine synthetase
15
glucosylceramide synthase
15
endonuclease
14
ACE
14
thioredoxin reductase
14
pyruvate kinase
14
ribonucleotide reductase
14
ribonucleotide reductase
14
alanine aminotransferase
14
diaphorase
14
creatine kinase
14
CD13
14
ricin
13
PI-PLC
13
prolyl endopeptidase
13
caspase-4
13
MMP
13
APC
12
S1 nuclease
12
histone acetyltransferase
12
kallikrein
12
peroxiredoxin
12
deaminase
12
neutral sphingomyelinase
12
PAM
12
firefly luciferase
12
caspase-4
12
ATP synthase
11
PNGase F
11
sphingosine kinase
11
aromatic L-amino acid decarboxylase
11
5'-nucleotidase
11
caspase-6
11
MEKK1
11
more...
Compound
DNA
2435
Dec
1925
calcium
1525
oxygen
1306
NBS
1277
retinoic acid
1163
sodium
861
Clin
859
cAMP
597
ATP
478
AMP
473
tyrosine
463
MTT
429
glucose
426
acetate
373
hydrogen
358
water
352
leucine
320
nitric oxide
309
phosphate
294
glutamate
273
iodine
256
iron
256
sulfate
248
GSH
235
GSH
235
serine
233
cysteine
229
GTP
226
bromide
212
potassium
199
ethanol
199
prostaglandin E1
197
zinc
195
copper
193
cGMP
189
arginine
185
lysine
182
H2O2
181
SDS
167
threonine
165
methionine
164
GM1
162
noradrenaline
160
alanine
157
MPP
153
MPP
153
Neuronal
141
TNF
134
ADP
131
galactose
129
Phe
126
ADP
125
ADP
125
nitrogen
121
5-HT
117
MEK
114
manganese
109
N-acetylcysteine
107
Gly
107
NH2
102
ACS
101
ACS
100
Asp
98
His
98
MPTP
96
PEG
95
COS
94
salt
92
glutamine
88
tryptophan
88
VMA
86
ammonium
82
NAD
80
Mg2+
79
DMSO
74
aluminum
72
tryptophan
72
cadmium
71
Adriamycin
71
GM3
71
urea
70
tryptophan
70
tryptophan
70
GABA
69
nickel
68
GABA
68
MDA
67
silver
66
proline
66
cobalt
66
L-DOPA
66
Insulin
66
creatinine
65
Carbachol
65
ADP-ribose
64
Dopamine
62
SOA
61
HVA
60
GM2
59
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
59
mercury
58
THP
57
GD3
56
DDP
56
THP
56
caffeine
54
NAD
54
pyrimidine
53
PEG
53
methanol
53
GDP
53
MAP
53
pyrimidine
53
NMDA
49
VP-16
48
Curcumin
47
aldehyde
47
CTX
47
TOF
47
TPA
47
TPA
46
Ins(1,4,5)P3
46
ACh
46
Triton X-100
45
ADR
45
gamma-aminobutyric acid
45
boron
44
glycerol
44
guanidine
44
pyridine
44
EDTA
43
Glutamate
43
CAT
42
CAT
42
CAT
42
acrylamide
42
EDTA
42
aldehyde
42
Ile
41
dUTP
41
nicotinamide
41
diacetate
39
N-(4-hydroxyphenyl)retinamide
39
glutamic acid
37
Bradykinin
37
HCl
37
salicylic acid
37
DAMGO
36
ICI
36
DEAE
36
GMP
36
PMA
35
homocysteine
35
selenium
34
CO2
34
Lead
34
ethyl acetate
33
uridine
33
acetic acid
33
more...