Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027819 (
neuroblastoma
)
27,800
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The adrenergic blocking agent methyldopa (
Aldomet
) is toxic to C-1300
neuroblastoma
cells in vivo. Four injections of
Aldomet
at a dose of 7.5 mg/injection were given over a period of 24 hr to C-1300
neuroblastoma
-bearing mice. This treatment killed a significant proportion of the C-1300
neuroblastoma
cells. Flow cytometric data suggest that sensitivity of tumor cells to
Aldomet
is not related to the cell cycle.
...
PMID:Toxicity of methyldopa (Aldomet) to mouse neuroblastoma cells in vivo. 686 Nov 22