Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027819 (
neuroblastoma
)
27,800
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Neuroblastoma
is the most common extracranial solid tumor of childhood originating from sympathetic nervous system cells.
Neuroblastoma
has also been diagnosed in conjunction with other congenital conditions such as Hirschsprung's disease, congenital hypoventilation disorder, and neurofibromatosis type 1.
Wolf-Hirschhorn syndrome
is a congenital disorder caused by microdeletion of short arm of chromosome 4 encoding MSX1 gene with characteristic facial features. We describe a child with dysmorphic features, developmental delay, mental retardation who developed
neuroblastoma
at 2 years of age and cytogenetic analysis of blood lymphocytes revealed an interstitial deletion of 4p(15,2). To best our knowledge, this report is the first report of
neuroblastoma
in a child with
Wolf-Hirschhorn syndrome
; and the reported association may be an important clue for oncological follow-up of patients with
Wolf-Hirschhorn syndrome
.
...
PMID:Neuroblastoma in a Child With Wolf-Hirschhorn Syndrome. 2808 42
