Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0027819 (
neuroblastoma
)
27,800
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Alveolar soft part sarcoma
(
ASPS
) is a rare malignancy with high rates of metastasis at presentation, defined by an unclear cellular origin and a unique unbalanced ASPSCR1-TFE3 translocation (der(17)t(X:17)(p11:q25)).
1
ASPS
is insensitive to chemotherapy and has been reported to involve the bladder only twice in the pediatric literature; once as a primary malignancy,
2
and once as a secondary malignancy after cytotoxic chemotherapy.
3
Herein, we report the third case of pediatric bladder
ASPS
in a female patient who received cytotoxic chemotherapy for low-risk
neuroblastoma
. This would represent the second case of pediatric bladder
ASPS
as a secondary malignancy after prior chemotherapy.
...
PMID:Second Reported Case of Pediatric Bladder Alveolar Soft Part Sarcoma as Secondary Malignancy After Prior Cytotoxic Chemotherapy. 3098 87