Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027651 (tumor)
685,946 document(s) hit in 31,850,051 MEDLINE articles (0.30 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 42492
Mol 33353
p53 26657
cytokine 11561
MRI 9703
CD8 9317
epidermal growth factor receptor 7167
lymphoid 7152
vascular endothelial growth factor 7031
vimentin 6565
CD4 6315
estrogen receptor 6216
AKT 6137
caspase-3 5993
collagen 5983
She 5926
Bcl-2 5804
osteosarcoma 5764
nodal 5572
tyrosine kinase 5430
mTOR 5265
HER2 5218
Ki-67 5176
p21 5074
interferon 5036
PI3K 4968
E-cadherin 4912
catenin 4658
EGFR 4582
tumor necrosis factor 4571
IFN 4537
cage 4471
TNM 4396
VEGF 4089
carcinoembryonic antigen 4017
TNF 3952
cytokeratin 3933
insulin 3921
cyclin D1 3822
CD34 3796
PTEN 3777
ERK 3745
histone 3710
MAPK 3696
ATP 3645
BRAF 3644
IL-2 3464
IL-6 3383
glycoprotein 3375
p16 3370
CD44 3348
PD-L1 3174
NMR 3128
colon carcinoma 3113
progesterone receptor 3102
matrix metalloproteinase 3095
PD-1 3090
IFN-gamma 3004
KRAS 2893
rhabdomyosarcoma 2885
FDG 2879
PEG 2852
ras 2845
mucin 2845
endoplasmic reticulum 2829
ACS 2804
interleukin-2 2771
alpha-fetoprotein 2755
epidermal growth factor 2721
CEA 2715
STAT3 2708
fibronectin 2705
HLA 2653
thymus 2638
chemokine 2562
desmin 2540
fused 2450
somatostatin 2442
MHC 2436
proteasome 2401
more...
Disease
tumor 685946
cancer 272229
carcinoma 56550
metastases 46273
breast cancer 44093
tumor growth 41526
adenocarcinoma 27974
tumorigenesis 27041
melanoma 26509
tumor progression 24176
hepatocellular carcinoma 22326
carcinogenesis 21494
lung cancer 19028
squamous cell carcinoma 17191
colorectal cancer 17079
prostate cancer 15437
lymphoma 15101
glioma 13459
primary tumor 12798
leukemia 11691
sarcoma 11581
gastric cancer 10997
renal cell carcinoma 10002
ovarian cancer 9624
colon cancer 9605
glioblastoma 8956
non-small cell lung cancer 8392
pancreatic cancer 8165
adenoma 7440
MCF 7430
lung carcinoma 7156
osteosarcoma 6675
brain tumor 6566
neuroblastoma 5855
bladder cancer 5785
multiple myeloma 5740
aggressiveness 5117
cervical cancer 5062
Hodgkin's disease 4894
liver cancer 4880
solid tumor 4707
epithelial ovarian cancer 4503
tumor angiogenesis 4239
residual disease 4162
dysplasia 4105
glioblastoma multiforme 3968
fibrosarcoma 3968
B-cell lymphoma 3958
meningioma 3943
retinoblastoma 3856
Epstein 3770
carcinoid 3734
acute myeloid leukemia 3639
liver metastases 3637
liver cancer 3624
schwannoma 3595
mammary tumor 3167
WT1 3154
endometrial cancer 3150
cirrhosis 3028
lung metastases 2989
hypertension 2954
astrocytoma 2913
anemia 2844
diabetes 2837
teratoma 2829
rhabdomyosarcoma 2816
hemangioma 2814
Hepatocellular carcinoma 2786
esophageal cancer 2758
uterus 2738
pheochromocytoma 2609
esophageal cancer 2571
leiomyosarcoma 2544
SCID 2512
mesothelioma 2506
skin cancer 2493
non-Hodgkin's lymphoma 2486
rectal cancer 2472
aggression 2470
more...
Symptom
pain 7664
abdominal pain 3288
headache 3033
anesthesia 2268
dyspnea 1948
vomiting 1887
diarrhea 1876
seizures 1863
weakness 1713
nausea 1570
fatigue 1551
anorexia 1301
cough 1271
cachexia 1153
starvation 1005
chest pain 964
back pain 910
discomfort 831
discomfort 822
exhaustion 794
collapse 726
splenomegaly 689
hemoptysis 655
nausea and vomiting 616
epigastric pain 603
ataxia 542
numbness 503
flank pain 479
erythema 477
bone pain 454
hoarseness 428
acidity 428
constipation 425
paresis 417
dizziness 408
respiratory distress 407
hepatomegaly 398
Ill 361
low back pain 360
shortness of breath 357
masculinization 342
vertigo 338
paresthesia 321
tinnitus 313
ENT 309
dysuria 306
abdominal discomfort 305
lethargy 274
HSA 265
syncope 249
overweight 244
exertional dyspnea 244
cancer pain 244
analgesia 239
hepatosplenomegaly 236
chills 225
paraparesis 222
acute abdomen 220
flushing 214
pelvic pain 207
colic 199
hypothermia 191
neck pain 189
functional recovery 172
polyuria 168
thinning 166
asthenia 165
spasm 160
sleepiness 158
dysarthria 157
hemiplegia 157
abdominal fullness 148
ophthalmoplegia 145
rhinorrhea 145
fever of unknown origin 144
arthralgia 144
facial pain 143
stridor 143
blurred vision 140
myalgia 134
more...
Drug
Dermatol 5209
IL-2 3520
IFN-gamma 2930
CSF 2569
Cardiovasc 2538
lysine 2313
ROS 1570
Adriamycin 1271
CTX 824
Taxol 788
Herceptin 706
Monit 703
ROC 655
Meth 639
MAP 613
CPT-11 586
ascorbate 582
Paraffin 545
ENT 523
vitamin E 522
ADR 514
CAM 510
Sorafenib 496
Bevacizumab 494
ADM 484
Imatinib 447
ABC 445
HCG 438
Gel 428
uPA 427
Docetaxel 421
G-CSF 398
ETS 395
GEO 377
NADH 368
Mutagen 351
Lipiodol 338
PTH 325
PTC 319
Cetuximab 319
Gefitinib 314
ALA 311
VCR 301
IFN-beta 298
Rituximab 281
Gleevec 273
Bortezomib 273
Glutathione 269
EE2 268
CTX 266
Leaf 260
Retinoic acid 256
CTX 255
Asn 253
caffeine 250
Photofrin 240
TAT 233
MRC 230
G418 226
Fluorescein 226
Portal 215
ICI 213
Indomethacin 213
Etoposide 207
p75 199
lactose 197
Irinotecan 197
BLM 194
CTC 188
NVP 187
DNase I 184
Albumin 177
Nephron 177
VCR 174
Erlotinib 173
Estrogens 171
Taxotere 167
CTC 163
Oxaliplatin 159
DM1 157
more...
Enzyme
ERK 21111
mitogen-activated protein kinase 10060
luciferase 5485
focal adhesion kinase 5148
protein kinase 5111
caspase-3 4651
protein kinase C 2938
ACS 2816
MEK 2660
proteasome 2451
PARP 2358
P-glycoprotein 2070
reverse transcriptase 1994
peroxidase 1896
APC 1837
urokinase-type plasminogen activator 1689
prostate-specific antigen 1657
catalase 1648
alkaline phosphatase 1604
lactate dehydrogenase 1527
thymidine kinase 1358
superoxide dismutase 1339
CD10 1311
glutathione S-transferase 1277
ATPase 1259
phosphatidylinositol 3-kinase 1225
cdc2 1209
caspase-9 1204
collagenase 1187
trypsin 1177
topoisomerase 1131
caspase-8 1077
AMP-activated protein kinase 1077
topoisomerase 1054
ornithine decarboxylase 1045
RNA polymerase 947
granzyme B 875
phosphoinositide 3-kinase 852
calcineurin 836
DNA methyltransferase 808
RNase 793
AMPK 787
MMP 772
alanine aminotransferase 772
RNase 730
thymidylate synthase 715
thrombin 650
beta-galactosidase 646
GSK 643
gamma-glutamyl transpeptidase 628
DNA polymerase 617
AMPK 615
matrix metalloproteinase 2 614
lysozyme 608
glutathione peroxidase 600
aspartate aminotransferase 593
enolase 560
prostate-specific membrane antigen 533
cathepsin B 531
acid phosphatase 523
plasmin 510
tyrosinase 506
renin 504
neuraminidase 500
carbonic anhydrase 492
succinate dehydrogenase 481
adenylate cyclase 456
aldehyde dehydrogenase 448
MDR 439
hyaluronidase 435
IKK 433
matrix metalloproteinase 9 432
aldehyde dehydrogenase 426
endonuclease 422
aldehyde dehydrogenase 411
aldehyde dehydrogenase 409
aldehyde dehydrogenase 409
NQO1 408
hyaluronidase 395
transcriptase 392
more...
Compound
DNA 58974
Dec 45106
Clin 36023
oxygen 12939
water 7811
glucose 6694
MDA 6249
calcium 6170
acetate 6163
MTT 5702
tyrosine 5321
PEG 5040
sodium 4448
TNM 4393
TNF 3952
phosphate 3837
PEG 3654
ATP 3649
iron 3355
sulfate 3182
methionine 3167
arginine 3129
lysine 3028
serine 2987
iodine 2887
ACS 2817
ACS 2805
nitric oxide 2533
cysteine 2466
His 2284
hydrogen 2196
Adriamycin 2183
galactose 2163
5-FU 2148
anthracene 2127
DBA 2121
leucine 2077
MEK 2048
GSH 1979
GSH 1979
retinoic acid 1945
threonine 1886
zinc 1886
ethanol 1872
DDP 1840
nitrogen 1801
bromide 1725
urea 1675
cAMP 1621
ADR 1597
ACTH 1405
copper 1379
alanine 1379
Asp 1314
hyaluronic acid 1312
DTPA 1191
Phe 1168
glutamine 1150
boron 1135
AMP 1086
Pac 1085
SCC 1068
SDS 1047
salt 1037
Gly 1029
DBA 1016
DBA 1016
tryptophan 1011
NH2 1008
pyrene 1003
silver 982
CO2 968
Thyroid 965
TPA 946
TPA 941
Estrogen 935
barium 928
pyrimidine 923
creatinine 916
pyrimidine 916
more...