Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 36-year-old man with anemia due to gastrointestinal bleeding, diagnosed to have a leiomyoma of the duodenum, is described. The conventional barium meal study and gastroendoscopy were useful for diagnosing the lesion. More invasive radiological methods, such as abdominal angiography and technetium-99m scintigraphy failed to detect the tumor. Early diagnosis and resection of the tumor would result in a good prognosis.
 ...
PMID:Leiomyoma of the duodenum--a case report. 182 70

There is good evidence that colonoscopy, in expert hands, is the most accurate investigation for the diagnosis of colorectal disease, and it also allows histological confirmation and therapeutic procedures to be carried out. Furthermore, by screening high-risk groups together with regular follow-up of patients with known colorectal neoplasia and surveillance of long-standing ulcerative colitis patients, it may be possible to reduce the incidence of colorectal cancer. However, at the present time, the lack of widespread availability and the variability in the quality of examinations precludes the employment of colonoscopy as the first-line investigation in colorectal disease. Flexible sigmoidoscopy combined with good quality double contrast barium enema is a reasonable alternative in the majority of cases, reserving colonoscopy for investigation of the elderly and high-risk patients, together with surveillance of patients with premalignant conditions. Technologically, colonoscopy has probably reached its peak and it is now necessary to make provision for more widely available colonoscopy services, provided by adequately trained endoscopists who can guarantee total colonoscopy in more than 90% of cases safely and rapidly. This requires structured training programmes for gastrointestinal physicians and surgeons and ultimately changes in patterns of working practice if adequate numbers of colonoscopy sessions capable of dealing with a steadily increasing workload are to be achieved.
 ...
PMID:Primary colonoscopy. 185 88

Pre-operative investigations, although providing useful information, were unreliable in predicting resectability in patients with malignant oesophageal lesions. Chest radiographs excluded metastasis and active tuberculosis. The barium swallow examination determined the length of the lesion and displayed various displacements, none of which excluded resectability. Tumour infiltration of the airways was the only change visible at bronchoscopy that contraindicated resection. Computed axial tomography was unreliable in excluding extra-oesophageal tumour extension and operability. As all these pre-operative investigations have their limitations in assessing operability, exploration of the lesion is essential to determine resectability for squamous carcinoma of the oesophagus, provided there is prior histological confirmation of a malignant oesophageal lesion.
 ...
PMID:Assessing operability in squamous carcinoma of the oesophagus. Are pre-operative investigations unreliable? 187 51

We report the first case of esophageal liposarcoma in Japan. A 46-year-old female was admitted to our hospital with chief complaint of protruding tumor out of the mouth. She had two episodes of protruding tumor after nausea in last 6 months. Barium swallow showed a large polypoid lesion of approximately 16cm in length with a stalk. By endoscopic examination, it was the polyp originated from the anterior wall of the cervical esophagus. It was covered with intact squamous epithelia, which had slight redness and erosion in the apex. Under general anesthesia the tumor was cut off at the base through the oral cavity. Specimen was 11 x 4 x 3cm in size and had yellowish cut surface. Histologically, the tumor composed of mature adipocytes and many atypical lipoblasts with spider web shaped cytoplasm. We diagnosed this tumor as well differentiated liposarcoma.
 ...
PMID:[A case report of esophageal liposarcoma]. 188

The barium enema is a safe and accurate diagnostic study of the colon but, in rare cases, complications may result. Many of these can be prevented by proper equipment and careful attention to technique. When a complication does occur, prompt recognition and management is vital in decreasing morbidity and mortality. Perforation of the bowel is the most frequent serious complication, occurring in approximately 0.02% to 0.04% of patients. Rarely the colon may burst due to excessive transmural pressure alone. However, a colon weakened by iatrogenic trauma or disease is more likely to perforate during an enema than is a normal healthy bowel. Injury to the rectal mucosa or anal canal due to the enema tip or retention balloon is probably the most common traumatic cause of barium enema perforation. Inflation of a retention balloon within a stricture, neoplasm, inflamed rectum, or colostomy stoma is particularly hazardous. Recent deep biopsy or polypectomy with electrocautery makes the bowel more vulnerable to rupture. The tensile strength of the bowel wall is impaired in elderly patients, patients receiving long-term steroid therapy, and in disease states including neoplasm, diverticulitis, inflammatory bowel disease, and ischemia. Intraperitoneal perforation leads to a severe, acute peritonitis with intravascular volume depletion. The ensuing shock may be rapidly fatal. Prompt fluid replacement and laparotomy are essential. If the patient survives the initial shock and sepsis, later complications caused by dense intraperitoneal adhesions may develop. Extraperitoneal perforation is usually less catastrophic but may result in pain, sepsis, cellulitis, abscess, rectal stricture, or fistula. Intramural extravasation often forms a persistent submucosal barium granuloma which may ulcerate or be mistaken for a neoplasm. The most dramatic complication of barium enema is venous intravasation of barium. Fortunately, this is quite rare as it may be immediately lethal. Most cases have been attributed to trauma from the enema tip or retention balloon, mucosal inflammation, or misplacement of the tip in the vagina. Bacteremia has been found in as many as 23% of patients following barium enema and, in rare cases, may cause symptomatic septicemia. Other less common complications include barium impaction, water intoxication, allergic reactions, and cardiac arrhythmias. Preparatory laxatives and cleansing enemas have been implicated in some instances of dehydration, rectal trauma, water intoxication, and perforation. Careful review of the indications for examination, previous radiographs, and clinical history will identify many of the patients at greater risk for complications so that appropriate precautions may be observed.(ABSTRACT TRUNCATED AT 400 WORDS)
 ...
PMID:Recognition and prevention of barium enema complications. 188 35

We report a case of primary testicular carcinoid with teratoma and review the literature. A 68-year-old man was hospitalized with an asymptomatic left testicular mass. Left radical orchiectomy was performed under a diagnosis of testicular tumor. Histologically, the tumor showed a typical appearance of teratoma with carcinoid components. Barium studies, computed tomographic scan could not demonstrate any other tumor anywhere else. He is now being followed at our clinic without any evidence of recurrence.
 ...
PMID:[Primary testicular carcinoid tumor with teratoma: a case report]. 189 15

Lymphaticovenous Communications were searched in the mammary glands of 24 bitches. Injections of indian ink into the interstice of living animals were followed after death by the filling of the veins with latex and barium sulphate. Afterwards, the used techniques were: microdissection, angiography, clarification and histological section. The results obtained would seem to prove the existence of Lymphovenous Anastomoses. The roles of these communications in the canine mammary gland neoplasia are discussed.
 ...
PMID:[Lymphaticovenous communication in the mammary gland of the female dog]. 189 26

It is the practice of some gynecologists and general surgeons to preoperatively evaluate the colon with a barium enema (BE) examination to exclude potential intestinal involvement or coexistent disease in patients undergoing pelvic or hernia operations. This practice appears to be based on anecdotal data with few studies specifically evaluating its usefulness. We retrospectively evaluated the records of 190 patients at William Beaumont Army Medical Center during 1986 to 1987 who received a preoperative BE prior to total abdominal hysterectomy (TAH) or inguinal hernia repair (IHR). The tumor registry charts of 59 patients diagnosed with carcinoma of the colon and rectum during the same period were also cross-checked to determine if any were detected during preoperative evaluation for TAH or IHR. BE findings were considered significant if they altered surgical management or asymptomatic carcinoma was detected. Of 86 patients screened before TAH by BE, eight had abnormal findings with subsequent colonoscopy revealing four with adenomatous polyps, one of which required surgical resection. Of 104 patients screened before IHR by BE, 15 had abnormal findings with subsequent colonoscopy revealing five patients with adenomatous polyps and two with adenocarcinoma. Screening preoperative BE had a low yield of clinically significant findings, which was even lower in the subgroup with carcinoma. There was no apparent relationship between findings and age in our study. Our results suggest that the use of routine preoperative BE has a low yield and should be performed only if clinical symptoms or findings suggest a need for this study.
 ...
PMID:The yield of barium enema in patients undergoing inguinal hernia repair or abdominal hysterectomy. 190 94

Colonoscopy is now the accepted diagnostic procedure for most colorectal diseases, although studies comparing sensitivity and specificity of double-contrast barium enema with total colonoscopy or combined procedures such as sigmoidoscopy and same-day double-contrast barium enema versus colonoscopy are still being performed. For diagnosis of diverticulitis and fistulas, however, barium enema is still the diagnostic procedure of first choice. Several studies have demonstrated a high sensitivity and specificity for ultrasonography in diagnosis of appendicitis. It seems that the number of unnecessary laparotomies in suspected appendicitis can be reduced by ultrasonography. In rectal carcinoma the therapeutic procedures are determined by the grade of local tumor infiltration and by tumor invasion of local lymph nodes. To predict the tumor stage, rectal endosonography has become the most reliable method. New genetical tests have been developed to diagnose presymptomatic stages in persons at risk of family adenomatous polyposis.
 ...
PMID:[Colorectal diseases: diagnosis]. 192 1

The present report describes a 69-year-old man displaying the clinical features of the Cronkhite-Canada syndrome. After taking medicine for the common cold, he suffered hypogeusia and watery diarrhea, eruptions on the lower extremities and an 8 kg loss in body weight. All his finger and toenails began to fall out. He underwent an upper gastrointestinal examination, upon which multiple polyps of the stomach were detected. Three years later, he again developed diarrhea, bloody stools, body weight loss and eruptions on the lower extremities. An upper gastrointestinal series showed a diverticulum of the esophagus and multiple polyps in the stomach. A barium enema examination revealed polyps throughout the entire colon. Endoscopical biopsy specimens revealed juvenile type polyps and adenomas. The patient was treated with predonine therapy and, in a few days, his symptoms improved. Following the predonine therapy, an upper gastrointestinal endoscopy revealed superficial esophageal cancer and early gastric cancer. The patient received successful surgical treatment. Macroscopically, the esophageal cancer was of the superficial type, and its histologic type was that of moderately-differentiated squamous cell carcinoma. The gross finding on the stomach cancer was one of superficial depressed type, and its histologic type was that of well-differentiated tubular adenocarcinoma. One year later, lung cancer was detected. The gross appearance of the resected lung tumor was one of a grayish-white color and the neoplasm was histologically diagnosed as undifferentiated carcinoma, small and large cell type. The coexistence of carcinoma of the gastrointestinal tract with Cronkhite-Canada syndrome has been reported in 21 cases. We have found no report, however, of lung cancer associated with Cronkhite-Canada syndrome. The case described herein is, therefore, the first case of Cronkhite-Canada syndrome to be associated with esophageal, gastric and lung cancer.
 ...
PMID:Triple carcinomas in Cronkhite-Canada syndrome. 194 50


<< Previous 1 2 3 4 5 6 7 8 9 10