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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two-dimensional echocardiography was used to study malignant metastatic neoplasms of the heart and great vessels in 20 patients, 13 males and seven females, whose ages ranged from 15 to 72 years. Five patients had lung cancer; two each had breast cancer, malignant melanoma, hepatoma and one each had gastric cancer, urinary bladder cancer, adrenocortical carcinoma, malignant lymphoma, angiosarcoma, fibrosarcoma, leiomyosarcoma; and two had cancers with unknown primaries. Tumor invasion was demonstrated echocardiographically in the left atrium in one each with breast cancer, fibrosarcoma and gastric cancer; in the right atrium in two with hepatomas; in the right atrium and right ventricle in one patient with adrenocortical carcinoma; in the left ventricle in one with lung cancer; and in the pulmonary artery in one with malignant melanoma. Massive pericardial effusion was observed in 11 of 20 patients; two with pericardial tumors including malignant lymphoma and lung cancer. We conjectured that metastatic tumors in the right cardiac cavities came through the inferior vena cava, and other tumors in the left atrium, left ventricle and pericardium developed from direct extension of the primary lesions. There was an 80% mortality of the patients during the observation period, and the average survival period after the diagnosis of cardiac metastases was 5.5 months. However, one patient was still living after two years of radiation therapy and chemotherapy. Echocardiography proved a useful, non-invasive means for the detection and follow-up observation of metastatic cardiac tumors.
J Cardiol 1990
PMID:[Echocardiography in patients with malignant metastatic neoplasms of the heart and great vessels]. 210 13

To determine the clinical advantages of transesophageal color Doppler echocardiography (TEE) for imaging cardiac tumors and left atrial thrombi, 24 cases with intra- or extracardiac masses were examined by transthoracic color Doppler echocardiography (TTE) and TEE before and after cardiac surgery. Five with left atrial myxomas, two with lung tumors, five with mediastinal tumors and 12 with mitral stenosis coexisting left atrial thrombi were included in this study. The echocardiographic findings of the cardiac masses were compared with the surgical findings in all cases. In all of the five cases with left atrial myxomas, the tumors were detected. However, the sites of attachment and a stalk in three cases were not observed by TTE. TEE clearly imaged the left atrial myxomas, and evaluated the size and shape of the tumors, the sites of their attachment and a stalk arising from the interatrial septum, and mobility in four cases, except for one in which there was a broad attachment to the endocardium. Mitral regurgitation was detected in only two cases using the color Doppler mode of TTE, but in all cases using TEE. Both techniques failed to recognize tissue characterization. Among seven cases with secondary cardiac tumors or mediastinal tumors, extracardiac masses were detected in five; however, an intracardiac tumor attached to the interatrial septum and an extracardiac tumor extending to the superior vena cava and an upper part of the right atrium could not be imaged using TTE. TEE detected all tumors at all sites in the heart and vessels, and estimates of their extents were in accord with the operative findings in 17 of 18 sites. One exceptional case had a tumor which extended to the right ventricle. Neither technique could detect infiltration of the heart which was present in five of the seven cases. Multiple left atrial thrombi were observed in eight of 12 cases, resulting in 21 thrombi and they were diagnosed by TEE in six of 12 cases. Thrombi, when attached to the left atrial posterior or inferior walls, were easily detected in four of five cases, but were not identified in four of six and in eight of nine cases at the lateral wall or in the left atrial appendage by TTE. However, TEE detected all thrombi in every site in the left atrium and left atrial appendage in 11 of 12 cases. TEE was thus superior to TTE in detecting cardiac masses, recognizing abnormal flow and estimating anatomical relationship between tumors or thrombi and cardiac structures.(ABSTRACT TRUNCATED AT 400 WORDS)
J Cardiol 1990
PMID:[Advantages of transesophageal color Doppler echocardiography in the diagnosis and surgical treatment of cardiac masses]. 213 59

Although spontaneous regression of cardiac rhabdomyoma has been reported, prognosis is still considered to be poor and surgery continues to be indicated. The experience with rhabdomyoma diagnosed in live infants over a 20-year period was reviewed. Diagnosis by angiography or echocardiography was accepted only if multiple tumors were present or if tuberous sclerosis was also diagnosed. Nine patients (3 diagnosed prenatally and the remaining 6 at age less than 8 months) were identified as having a total of 24 tumors. Measurements in 2 planes demonstrated at least some evidence of regression in 24 patients (100%), with 20 of 24 having complete resolution. One patient required delayed surgery for excision of a subaortic ridge that appeared at the site of a resolved tumor. Our findings suggest that pediatric cardiac rhabdomyoma is most often a benign condition in which spontaneous regression is the rule. Surgery is recommended only for patients with refractory dysrhythmias or severe hemodynamic compromise.
Am J Cardiol 1990 Nov 15
PMID:Natural history of cardiac rhabdomyoma in infancy and childhood. 189 6

We report the case of a 4-year old child who underwent echocardiographic examination which revealed a multicystic tumor mass involving the infero-lateral wall of the left ventricle. It was necessary to perform a biopsy to make a reliable diagnosis. Histological studies indicated haemangiomatous and fibrous tissue of benign origin. The extensive involvement of the left ventricular free wall did not favour resection so we advised periodic clinical examination and Holter ECG to highlight any eventual occurrence of hypo or hyperkinetic arrhythmias.
G Ital Cardiol 1990 Jul
PMID:[Cardiac angioma. A case report and review of the literature]. 224 3

The spread of metastatic cancer to the pericardium is the most common cause of cardiac tamponade in medical inpatient settings. Lung cancer, breast cancer, and the hematologic malignancies account for some three quarters of the cases. Occasionally, usually in lung cancer, the pericardial involvement is the first clinical presentation of the neoplastic disease. Differential diagnosis includes radiation pericarditis and cardiac toxicity from chemotherapeutic drugs, as well as any of the causes of pericardial disease in patients without neoplasm. Idiopathic nonneoplastic, noninflammatory pericardial effusion is surprisingly common in cancer patients. The initial cardiac tamponade may be managed with either needle tap or subxiphoid pericardiostomy. Pericardiocentesis, performed with echocardiographic guidance and followed by percutaneous catheter drainage for several days, is safe and effective in neoplastic pericardial effusion. It may be the only local therapy that is needed. Further local treatment, for those patients who develop recurrent cardiac tamponade after an initial drainage procedure, may include tetracycline sclerosis of the pericardial space, instillation of cancer chemotherapeutic agents, radiation therapy, and pericardiectomy. No controlled clinical trials of these methods of treatment are available. The choice of therapy is based on various considerations in individual patients, particularly the patient's general condition and the likelihood of a long-term response to treatment of the systemic neoplastic disease.
Cardiol Clin 1990 Nov
PMID:Neoplastic pericardial disease. 224 21

We report the case of a 37 years old woman with pheochromocytoma of the adrenal gland, with acute circulatory failure and pulmonary oedema. Its originality lies, besides the rare circumstances of diagnosis, in the echographic aspect of the left ventricle with an apical myocardial infarction with both severe apical hypokinesia and compensating basal hyperkinesia. In the literature the most frequent aspect of catecholamine cardiomyopathy is a large uniform dilatation of the left ventricle with often wall hypertrophy. After surgical ablation of the left adrenal gland tumor, we observe quickly a complete normalisation of the picture and especially the echocardiogram. The cardiomyopathy and the pulmonary oedema can result from the specific action of the excess catecholamines on the myocardial cells and the pulmonary capillaries.
Ann Cardiol Angeiol (Paris) 1990 Sep
PMID:[A rare cause of acute circulatory failure with pulmonary edema: catecholergic cardiomyopathy of pheochromocytoma]. 226 6

Benign non myxomatous cardiac tumors are rare. Between 1968 and 1988, 9 patients presenting benign non myxomatous cardiac tumors were operated in our institution. Tumors were: 2 rhabdomyomas, 2 lipomas, 2 fibromas, 1 pheochromocytomas, 1 mesothelioma and 1 papillary fibroelastoma. Total excision was possible in all cases but one (multiple fibromas). We hereby present a review of the literature on the subject. We focalize on the new imagery techniques in order to help the diagnosis and on the new surgical possibilities (cardiomyoplasty) which make possible complete surgical excision.
Ann Cardiol Angeiol (Paris) 1990 Sep
PMID:[Benign tumors of the heart (excluding myxoma). Experience with 9 surgically treated cases]. 226 9

The usefulness of different radiologic studies in localizing the tumor was evaluated in 26 patients with a firmly established diagnosis of pheochromocytoma. The site of the lesion was correctly identified in 8% of the cases by the plain abdominal x-ray films: in 11% by the plain thoracic films; in 34% by uronephrotomography; in 88% by angiography and in 6 patients (100%) in whom computed tomography scans (CT) were performed. The tumors were intra-adrenal in 19 patients and extra-adrenal in the remaining 7 cases. Of the latter, two were found in the organ of Zuckerkandl, two were abdominal para-aortic, two others in the para-aortic region of thorax, and one with intra an extra-adrenal tumors. It is concluded that CT scans are quite successful in preoperative localization of pheochromocytoma. The non-invasive nature of the technique makes it the method of choice in the anatomical localization of this type of tumors.
Arch Inst Cardiol Mex
PMID:[The importance of radiology in the localization of pheochromocytoma]. 226 79

We reviewed our clinical experience in 24 patients with cardiac myxoma. There were 8 males and 16 females, their ages ranged from 14 to 73 (mean, 48) years. Prior to echocardiographic examination, cardiac myxoma was suspected clinically in only 2 cases. The remaining patients were initially diagnosed as having mitral valvar disease (9 cases), infective endocarditis (3 cases), congestive cardiomyopathy (4 cases), pericardial effusion (1 case), systemic embolism of unknown cause (1 case), cerebrovascular accident (2 cases), ventricular septal defect (1 case) and Ebstein's malformation (1 case). The tumor was in the left atrium in 16, in the right atrium in 2, in the biatrium in 1, while one was in the right ventricle and peripheral arterial occlusion had been produced by myxoma without demonstrable cardiac tumors in the other two. Twenty-two patients underwent open heart surgery for excision of myxoma and there was no surgical mortality. Abdominal embolectomy was carried out in 2 patients; one of these 2 patients survived and 1 died. Follow-up for a mean period of 32 months (range 2 to 99 months) was possible in in 18 patients with no evidence of recurrence. We conclude that cardiac myxoma may mimic many cardiovascular diseases, so a high index of suspicion is important for its diagnosis. Echocardiography is the most useful diagnostic screening tool.
Int J Cardiol 1990 Dec
PMID:Cardiac myxoma--clinical experience in 24 patients. 228 91

Endocarditis due to the streptococcus Bovis is an affection which is more and more often recognized and whose link with the colic tumor pathology has been well established those last few years and confirmed in this study with a frequency of 60 p. cent. However, few studies have stated the gravity of the heart affection in streptococcus Bovis septicaemias. In this series of 10 streptococcus Bovis septicaemias, the valvular affection is frequent and serious. The vegetations are found in 9 cases out of 10. The aortic affection is slightly more frequent (8 times out of 10), against 7 times out of 10 for the mitral affection (double mitroaortic affection, 6 times). A valve replacement due to sub-acute or chronic cardiac failure was necessary in 6 cases out of 9, that is 66 p. cent. The mortality was nil.
Ann Cardiol Angeiol (Paris) 1990 Nov
PMID:[Incidence and severity of cardiac involvement in Streptococcus bovis septicemia. Report of 10 cases]. 229 15


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