Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0027651 (tumor)
685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Twelve patients with facial palsy after resection of acoustic neuromas were treated by hypoglossofacial anastomosis. The nerve anastomosis were performed 1-2 months after resection of the tumor in 10 cases (group A). Two cases (group B) had the anastomosis performed more than 2 years after damage to the facial nerve. All the cases had been followed for more than 9 months. The results of reinnervation of the paralyzed facial muscles were quite satisfactory, i.e., over 80% of the cases obtained a good functional recovery. Although there was a 2-month delay in functional recovery of group B patients, the final results were practically the same in both groups. Therefore, the effect of the duration of the paralysis of the facial nerve seems to be less important in facial nerve surgery than in nerve surgery of the extremities. The procedures of anastomosis of descendens hypoglossi to the distal stump to the hypoglossal in 7 of the 10 patients using the hypoglossal as the donor nerve was of little help in prevention or restoration of the hemiatrophy of the tongue. In spite of long-term inconvenience in speaking and eating after section of the hypoglossal, all the patients were able to make enough adjustments about 2-3 months after nerve surgery.
...
PMID:Hypoglossofacial anastomosis for facial palsy after resection of acoustic neuroma. 669 25

Blood gas analysis was used to assess the value of cryolytic endobronchial disobstruction in functional recovery of the reventilated lung parenchyma, with particular reference to the real improvement brought about in blood gas equilibrium by reventilation. Blood gas analysis was carried out in 5 cases of malignant tracheobronchial neoplasia (3 with atelectasis or subatelectasis) before and after disobstruction. Improved gas exchange, primarily in the form of better blood oxygen values, was noted in all cases, with a mean improvement of 28% in 3 cases and 7% in 2. It should be noted, however, that there was no correspondence between the results and the presence or otherwise of radiological evidence of atelectasis prior to the treatment.
...
PMID:[Effect of pulmonary reventilation on gas exchange after cryolytic removal of obstruction in endobronchial tumors]. 678 50

We present a case of crossed aphasia and reversed laterality in a 60-year-old right-handed man. Neuropsychological assessment was conducted both prior, and three months subsequent, to the removal of a right temporal lobe tumor. Results, using the Luria-Nebraska Neuropsychological Battery, Wechsler Memory Scale and WAIS Block Design, plus various drawings from copy and to command revealed: (1) presurgery Luria profile very close to the mean profile for dominant temporal lobe dysfunction, (2) preserved visuospatial and visuoperceptive skills, (3) preserved limb praxis, and, (4) good postsurgery functional recovery. These findings are discussed in relation to literature on crossed aphasia and reversed laterality.
...
PMID:Neuropsychological analysis of a case of crossed aphasia: implications for reversed laterality. 710 47

A series of 33 patients with 35 acoustic nerve tumors is reviewed. Tumor size was estimated from computerized tomography (CT) scans, and its influence on anatomical and functional preservation of the facial nerve was assessed. Six tumors (one invading the petrous bone, three medium and two large tumors) were not detected on CT scans. The translabyrinthine approach was used in seven instances (one small and six medium tumors) and the suboccipital transmeatal approach for 28 tumors (seven medium and 21 large tumors). Anatomical preservation of the facial nerve was achieved in 83% of operations for tumor removal, two of which were subtotal. A further two patients underwent subtotal removal, but the facial nerve was destroyed. Large tumors carried an increased risk of damage to the facial nerve, but even in this group the nerve was preserved anatomically intact in 70% of cases. Damage to the facial nerve occurred more frequently in patients with preoperative evidence of facial weakness; however, this factor did not appear to influence functional recovery of the facial nerve, provided that the nerve was intact at the end of the operation. A simple grading system for facial nerve function is described. Ony 76% of anatomically intact facial nerves showed any evidence of function 1 month after surgery. Postoperatively, facial function improved with time. At the latest review, 45% of these patients had normal facial function or mild facial weakness (Grades I and II).
...
PMID:Facial nerve preservation during surgery for removal of acoustic nerve tumors. 714 55

A case of facial nerve neurilemmoma within the temporal bone is reported. The patient is a 47-year-old female complaining of 10 years' history of left facial palsy. CT and MRI examinations showed an enlarged mass of the tympanic cavity protruding into the petrous bone, mastoid cavity and external auditory meatus. An open biopsy of the tumor at the external auditory meatus revealed neurilemmoma. The tumor was totally removed by a retroauricular approach. Five months after surgery, both the cross nerve graft using the peroneal nerve and the temporal muscle transfer, method modified by Johnson were performed for the functional recovery of facial palsy.
...
PMID:[Neurilemmoma of intra-temporal facial nerve:case report]. 748 74

Facial nerve specimens removed from ten patients who underwent hypoglossal-facial nerve anastomosis for facial palsy following removal of cerebellopontine angle tumors were studied histologically. Facial nerve function prior to the anastomosis surgery and the degree of postoperative functional recovery were compared with the histological results. The recovery of facial palsy after the anastomosis surgery was excellent or satisfactory in nine patients and the endoneurium within the nerve fascicles was well-preserved. The recovery of facial palsy was poor in one patient who had severe fibrosis of the endoneurium. The histological and ultrastructural features of the facial nerve were closely related to the occurrence of facial palsy prior to tumor removal, the status of the nerve after tumor removal, and the interval between tumor removal and anastomosis surgery. Based on these histological and functional relationships, the timing and indications for anastomosis surgery are discussed.
...
PMID:Functional and histological evaluation of the facial nerve in patients who have undergone hypoglossal-facial nerve anastomosis after removal of cerebellopontine angle tumors. 760 95

Transfrontal approach is the way available for microsurgical removal of retrobulbar tumor. The tumor can be completely extirpated with minimal injury upon the optic nerve, oculomotor nerve, ciliary ganglion and ophthalmic vessels as well as ocular muscles. Thirty-two cases of retrobulbar tumor (cavernous hemangioma, telangioma, glioma, lymphangioma, neurinoma, neurofibroma and rhabdomyosarcoma) were operated through this approach with microsurgical techniques. Follow-up shows that in all cases no recurrence occurs in 3-9 years and reveals that in 29 cases the preservation or functional recovery of vision and ocular movement are satisfied. One case of rhadomyosarcoma and two cases of glioma lose their vision for the partial resection of optic nerve which was invaded by the tumor. It is useful to detect undesirable dissection of tumors from its surrounding oculomotor nerves with evoked potential monitoring.
...
PMID:[Transfrontal approach for the microsurgery of retrobulbar tumor]. 774 23

We performed a sequential neuropsychological tests before and after neurosurgical intervention on a 69-year-old patient with left hemineglect syndrome caused by metastatic right temporal papillary carcinoma. The tests performed before operation and computer tomography revealed marked impairment in visuospatial reasoning, spatial orientation, visual perception, visuoconstructional praxis, effort emory, as well as block design in Wechsler Adult Intellectual Scale-Revised, all of which suggested right temporo-parietal lesion. Left spatial neglect was obviously demonstrated by the Line Cancellation Test, Watch Test, and clinical observation. After surgical debulking of the tumor, his performances on most of the tests were improved. Our study demonstrated that the conventional neuropsychological test is not only useful for localizing the cerebral lesion but also valid for the assessment of functional recovery after treatment, a role that can never be replaced by any other modern technique.
...
PMID:[Neuropsychological assessment in a patient with left hemineglect syndrome--a case report]. 776 63

Lung nodules in patients with a history of malignancy usually require tissue diagnosis that will provide prognostic information and dictate further therapy. Patients with a favorable tumor histologic condition and limited tumor burden were often considered for resection. This is usually accomplished by wedge resection through open thoracotomy when the lesions were peripheral. However, complications related to open thoracotomy often exclude poor-risk patients, especially those with impaired pulmonary function. Currently, technique of thoracoscopic resection is opening up new vistas and unimagined options for the thoracic surgeon in the management of pulmonary diseases. With the application of thoracoscopy and small incisions, it is now possible for the thoracic cavity and its contained organs to be thoroughly explored. Our recent experience with the thoracoscopic resection as a primary treatment for lung metastases is the focus of this report. Forty-seven patients with a history of malignancy and new lung metastases underwent this type of resection. Postoperatively, there is less pain, quick functional recovery, and excellent cosmetic healing. It is a safe and promising approach.
...
PMID:Application of thoracoscopy for lung metastases. 763 11

We are reporting the functional outcome of 69 of 86 patients affected by intramedullary spinal cord tumors who underwent surgery at our department during the period of 1984 to 1992. The results on 17 patients affected by hemangioblastomas and cavernomas were excluded from this study and will be published separately. Twenty-eight patients had astrocytic processes; 34 had ependymoma; 4 had lipoma; 2 had neurofibroma; and 1 had oligodendroglioma. The overall rate of "radically" resected tumors was 55.1%, as opposed to 17.4% "quasiradically," and 27.5% of "partially" resected processes. There was one postoperative death. Five other patients, affected by anaplastic astrocytomas, died because of tumor progress within 16 months from the operation. A postoperative functional assessment showed that the function of the upper and lower extremities had deteriorated in 65.4 and 55.1% of the patients; a respective functional deterioration by 1 degree of the scale of Cooper and Epstein was registered in 88.8 and 86.8% of the patients. The patients who recovered improved within a period of 6 to 18 months, whereas the function of the dorsal columns was impaired the longest. At follow-up (mean, 54 mo; range, 8-107 mo), the functional recovery (as compared with the preoperative status) was as follows: upper extremity, 17.1% of the patients were improved, 55.5% were unchanged, and 31.5% were worse (89.4% by 1 degree); lower extremity, 22.4% of the patients were improved, 51.5% were unchanged, and 29.4% were worse (most by 1 degree). Surgery on tumors of the cervicothoracic and upper thoracic region carried a relatively higher morbidity in this series.(ABSTRACT TRUNCATED AT 250 WORDS)
...
PMID:Surgical management of intramedullary spinal cord tumors: functional outcome and sources of morbidity. 793 55


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>