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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The frequencies of fever, parenchymal infiltration, and bacteremia were studied prospectively after 100 flexible fiberoptic bronchoscopies performed transnasally under topical anesthesia. Fever occurred after 16 per cent, and parenchymal infiltration, after 6 per cent of the procedures. Most complications were mild and transient; however, one patient developed rapidly progressive pneumonia and died. No organisms were isolated from cultures of blood drawn at the time of the procedure or during complications. The organisms most commonly isolated from the sputum of the patients who developed pneumonia were the aerobic and anaerobic bacteria normally found in the mouth. Isolation of a significant pathogen before the procedure did not predispose to development of a complication. Advanced age (greater than 60 years) and the endoscopic findings of abnormalities were significant predisposing factors. Bronchial brushing, but not bronchial biopsy or bronchial washing, was associated with significantly higher complication rates in patients with bronchial carcinomas than in those without a neoplasm. The mechanism of the fever and parenchymal infiltration is thought to be related to obstructive atelectasis and infection produced by organisms present in the airways at the time of the procedures.
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PMID:Fever and pneumonia after flexible fiberoptic bronchoscopy. 114 84

If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic spread to be amenable to local treatment. Rectal cancer, usually regarded as being slightly radiosensitive when treated by external irradiation, proves to be highly radiosensitive in the case of early cancer treated by intracavitary irradiation. This method is able to control a large amount of limited polypoid and ulcerative adenocarcinomas. In a series of 133 cases followed more than 5 years, the rate of death from cancer is only 9%, and the 5-year survival rate is 78%. As compared with local exision or electrocoagulation, intracavitary irradiation has several advantages. It does not require colostomy nor anesthesia. Contact x-ray therapy is an ambulatory treatment applicable even to elderly and fragile patients. There is no danger of fistula in the case of tumor of the anterior wall in female patients. It preserves all the chances of cure by subsequent surgery in case of failure.
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PMID:Intracavitary irradiation of early rectal cancer for cure. A series of 186 cases. 115 30

The CO2 surgical laser and microscope assembly have been used to excise carefully selected T1 carcinomas of the membranous portions of the cord. Healing has been prompt and return of function satisfactory. General anesthesia and suspension laryngoscopy have provided excellent definitions of the lesions; the laser has provided a precise method of dissection. Initial results have been excellent and long term results will depend on the accuracy with which the margins of the tumor are defined and the presence or absence of the tendency of the larynx to produce multicentric disease.
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PMID:Laser excision of carcinoma of the larynx. 116 Apr 59

Prolapsed pedunculated leiomyomas of the uterus can best be managed by simple vaginal myomectomy. It is safe, easily performed and generally requires no anesthesia. The risk of complications during and after a major abdominal surgical procedure in the face of infection and anemia is eliminated. Interval hysterectomy, if indicated, may be done four to six weeks after vaginal myomectomy without incurring the additional risk of increased operative morbidity. Additional surgical procedures are not indicated if the pelvic examination remains normal. When large leiomyomas are encountered, the pedicle may not be accessible. Confronted with such a situation and continued blood loss and sepsis, we elected in three patients to replace the tumor within the endometrial cavity and close the cervix. Immediate hysterectomy was then carried out. Blood replacementd antibiotic coverage were instituted in advance of any operative procedure. Other pathologic entities must be kept in mind as a source of uterine bleeding that may be found in association with pedunculated myomas.
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PMID:The surgical management of prolapsed pedunculated submucous leiomyomas. 116 67

The entitiy of hamartoma of the lung is defined and frequency, location, tissue components, and roentgenographic appearance are described. The clinical significance of this disease in one case of endobronchial location is discussed. It is reported about an own observation of an endobronchial, pendulous, polypoid chondrolipoma (hamartoma) which is located near the tracheal bifurcation. The following points about roentgenological procedures and diagnostic interpretation are concluded: 1. Indirect signs for occlusion of the right main stem bronchus by a pendulous polypoid hamartoma are a small-appearing right hilus and the overinflation of the right upper lobe caused by a valve-like mechanism. 2. The postoperative overinflation is located beyond the stalk of this lesion which originates in the right upper lobe, although the mass of this pendulous tumor is located in the right main stem bronchus, respectively in the right lower lobe bronchus (documented by tomography and surgery).3. The recognition of shape and inferior limitation of polypoid endobronchial neoplasmsis achieved best by tomography which is a simple, innocuous diagnostic procedure. Bronchoscopy and biopsy clarify preoperatively the criteria of the lesion.4. Bronchography of poststenotic areas of the lung in polypoid pendulous endobronchial neoplasm is contraindicated on account of threatening respiratory insufficiency.5. Development of an alternating broncho-tracheal syndrome must be considred in patients which undergo endoscopy in anesthesia.
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PMID:[Pendulous endobronchial chondrolipoma (hamartoma) near the tracheal bifurcation (author's transl)]. 117 41

The aim of this technical note is to show that ketamine hydrochloride anesthesia, owing to the preservation of muscle tone, enables one to safely and comfortably carry out gaseous encephalography on a simple radiological table in the toddler or child. However the authors very strictly select the indications for this investigation. Whenever the child's clinical condition leads one to suspect intracranial hypertension and/or a cerebral tumor, they think it more prudent, owing to the vasopressor effect of ketamine hydrochloride and a possible elevation in the cerebrospinal fluid pressure, to transfer the child to a specialized neuroradiological center, where the investigations would be carried out under the best technical conditions, and close to a neurosurgical unit which is capable of intervening rapidly in case of complications. The authors voluntarily limit their indications to children suffering from psychomotor retardation, epilepsy or neurological disorders which make one suspect a congenital malformation.
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PMID:[Gaseous encephalography under ketamine hydrochloride general anesthesia in the child (author's transl)]. 119 15

The accuracy of needle biopsies with the disposable biopsy needle TRU-cut was compared to the results of the microscopic examinations of excisional biopsies obtained after the needle biopsy in 276 patients. The diagnostic accuracy in relationship to the diameter of the lesion is listed for 140 patients with carcinoma of the breast, for 72 patients with benign tumors of the breast and for 64 patients with well localized palpable fibrocystic disease. In our experience, the following pre-requistes are necessary to obtain a high diagnostic accuracy for the needle biopsy: 1. A well filled circumscribed, well palpable nodule of uniform consistency. 2. A superficial site close to the skin. 3. A diameter of more than 2 cm. 4. Some experience with the use of the instrument. Needle biopsies of the breast are indicated for skin metastases, recurrences in the scar, and for in-operably advanced tumor or patients who should not have general anaesthesia. Needle biopsy as the biopsy method for a primary plan of management is only relatively indicated in large carcinomas of the breast, or smaller tumors located close to the skin, or tumors which are well accessable in a small breast. The needle biopsy is not suited for the diagnosis of benign tumors of the breast, fibroadenomas, lipomas, or papillomas since complete excision of these lesions is the aim of management. In fibrocystic disease, needle biopsy is not indicated. This clinical or radiological localized finding may correlate to variable microscopic entities with different plans of management. The very small portion of the process shown in the needle biopsy is insufficient in fibrocystic disease. An absolute contra-indication to needle biopsy of the breast is the diagnosis of obscure disease on the breast.
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PMID:[The value od needle biopsy for the microscopic diagnosis of diseases of the breast (author's transl)]. 121 54

A case of 58 year old female with chronic spinal epidural abscess demonstrating rapid progression of complete spinal cord paralysis without remarkable recovery by laminectomy was reported. Patient had a large subcutaneous abscess on left back, ten years ago. Three months before admission she fell down from stairs and had a compression fracture on the seventh thoracic vertebra. She has been troubled with slight spinal ache and left lower back pain since the fall accident. One month before admission she suddenly noted severe lower back pain with radiation to left side and the pain became more severe. Three weeks after she noted fecal retention without urinary retention. Five days before admission she noted gait disturbance accompanied by numbness of both foots. Three days later she developed inability to urinate and the same day, over the coure of a few hours, she became total paraplegia and anesthesia below the waist. On admission neurological examination and myelography disclosed complete spinal subarachnoid block with flaccid total paraplegia and anesthesia below the lower chest. The clinical diagnosis was spinal epidural mass lesion, probably neoplasm. Laminectomy from Th-6 through Th-9 was performed the next day: three days after complete paralysis. The epidural abscess included pus and soft granulation tissue was found and totally removed. Staphylococcus aureus sensitive to penicillin, chloramphenicol etc. was isolated on becteriologic culture. On seven months after operation, sensory and deep reflexes were considrable improved, but she remained paraplegic without sphincter control. Dicussion were made on the incidence, pathogenesis.
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PMID:[Chronic spinal epidural abscess (author's transl)]. 123 82

Lung cancer is rarely diagnosed and treated while still localized. Sputum cytology allows detection of radiologically occult tumors but conventional endoscopic procedures frequently prove inadequate for localization. It is the purpose of this report to outline the endoscopic observations and methods we have developed in successfully localizing 17 consecutive, radiologically occult carcinomas discovered in the sputum of 15 patients. A detailed examination of the upper respiratory tract demonstrated occult tumors in two patients. A segment by segment fiberbronchoscopic study under anesthesia allows multiple brushings and meticulous handling of specimens. Lesion localization is provided as well as identification of synchronous second primary tumors. Biopsies at the lobar spur and carina assist in determining the proximal extent of carcinoma in situ at potential surgical margins. Newer methods should enhance our recognition of inapparent carcinoma in situ allowing more efficient and more accurate tumor localization and a better appreciation of its extent.
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PMID:New horizons in lung cancer diagnosis. 124 75

Female CBA and WHT mice with tumors transplanted into the right leg were immobilized in insulated capsules. Tumor blood flow, blood pressure, and core and tumor temperatures were monitored prior to and during anesthesia with either Nembutal or urethane. Nembutal caused a 5 degree C drop in both core and tumor temperatures in 20 minutes. Urethane induced a small fall in temperatures. Urethane initially caused a small drop in blood pressure followed by recovery; Nembutal caused a steady fall in blood pressure to 50% of resting value.
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PMID:Changes in mouse blood pressure, tumor blood flow, and core and tumor temperatures following nembutal or urethane anesthesia. 125 Oct 23


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