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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The woodchuck or groundhog (Marmota monax) has been used as a biomedical model for studies of obesity and energy balance, endocrine and metabolic function, central nervous system control mechanisms and cardiovascular, cerebrovascular and neoplastic disease. Methods of care of a woodchuck colony, techniques for handling, restraint, anesthesia, blood sampling and breeding were developed.
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PMID:The woodchuck, Marmota monax, as a laboratory animal. 52 75

Five cases of pheochromocytoma are described in which sudden death was the form of the initial clinical presentation in almost all of them. After a brief review on the history and the incidence of the tumor within the general population, diverse cases are analyzed from a clinical point of view and in relation to the data appeared in the literature. In the analysis of the symptoms emphasis is placed on the important psychomotor manifestations which are present in the majority of those patients and which causes serious difficulties in the initial diagnosis. All of the patients showed signs of shock at the time of being observed or during the course of this observation, and in the majority of them the presence of acute pulmonary edema was confirmed; facts which we attribute to an initial hypertensive episode associated to a left heart failure. The onset of the crisis in two patients was related to known triggering factors: anesthesia and sulpiride. In other two patients associated conditions were diagnosed: medullary carcinoma of the thyroid gland in one of them, and cystic necrosis of the middle layer of the aorta in the other.
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PMID:[Pheochromocytoma and sudden death (author's transl)]. 52 72

Thoracoscopy with a single opening was carried out under general anesthesia with a cold light thoracoscope of 7 mm in diameter. Biopsies were taken under visual control for optical and electron microscopic examination. In a series of 40 mesotheliomas, 30 patients with pleural effusion underwent 36 thoracoscopies. In 29 patients the macroscopic lesions were compatible with the diagnosis of mesothelioma. The most specific aspects consisted in white-yellowish nodules, almost translucent, arising from the parietal pleura (9 patients). Another typical pattern, a dense pleural thickening, was found in 10 patients. In the remaining patients, the lesions observed were less specific. The biopsy was positive in 35/36 thoracoscopies (97%). A talc poudrage was carried out in 10 patients: their mean survival was 458 days. In ten matched mesothelioma patients who underwent pleurectomy the mean survival was only 395 days. In 12 patients at an early stage, the visceral pleura was not involved by the tumor: their mean survival was 636 days. In 11 patients both parietal and visceral pleura were involved by the tumor: their mean survival was 138 days: (p less than 0,001). It is concluded that in mesothelioma pleural effusions, thoracoscopy is a safe and efficient procedure in order to reach a precise diagnosis, prognosis and efficient palliative treatment of the effusion.
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PMID:[Thoracoscopy in pleural mesothelioma. Diagnostic, prognostic and therapeutic interest (author's transl)]. 55 11

The intracranial arterial obstructions (narrowing or occlusion) found with intracranial tumors are rarely reported. Our 25 cases and those of the literature enable us to draw a statistical view of these facts. Meningiomas and gliomas are often concerned, and they principally involve the main arteries at the base of the brain. The practical interest in such pathology concerns: the risk of a fall in blood pressure during general anesthesia which may result in occlusion of a narrowed artery; the need to estimate the pathological state of one or several arteries passing by a tumor which must be removed; and the possibility of providing an extra-intracranial arterial bypass if necessary.
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PMID:Narrowing and occlusion of arteries by intracranial tumors. Review of the literature and report of 25 cases. 56 34

Within one year 38 patients with bladder tumors--most malignant--were treated by argon-laserbeam (6 Watt and 15 Watt). We now survey altogether 45 endoscopic operations. To bring the laserbeam into the waterfilled bladder, we use a special light-conductor and a normal operation-cystoscope. Laser therapy takes place after conventional electro-resection (TUR) by coagulation of the tumor ground or independently by destroying small relapses of tumors. We have observed some advantages of argon-laser treatment compared to electro-surgery: 1. No convulsions of bladder muscle with the danger of perforation, sometimes produced by current impulses. 2. Painlessness. Laser treatment is possible without anesthesia. 3. More therapeutic range. 4. Cases of absence of recidivation. We hope that the new therapy will be able to reduce the recidivation of bladder tumors and to improve the poor results of operative treatment.
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PMID:[Transurethral laser treatment in bladder neoplasms]. 56 24

Accurate knowledge about the morphology and degree of infiltration of a bladder tumor is an essential prerequisite to correctly plan, and forecast the results of, the treatment of these tumors. Among the radiological investigations double contrast cystography is superior to excretory cystogram or conventional cystogram in delineating the morphology of bladder tumors. Polycystography demonstrates, radiologically, the degree of infiltration of a bladder tumor. By simultaneously performing these procedures, the information necessary for planning the treatment is obtained in a single sitting, with one catheterization. This procedure was performed in 15 patients, in good correlation with other parameters such as cystoscopy, bimanual examination under general anesthesia and biopsy.
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PMID:Simultaneous double contrast cystography and modified polycystography in the evaluation of bladder carcinoma. 59 Dec 40

The author studied the remote results of the treatment in 1358 breast cancer patients, 554 of them were operated under ether-nitrogen-oxygen anesthesia and 804--under fluothane-nitrogen-oxygen anesthesia. The patients were subjected only to the Halsted mastectomy. Both groups of patients were identical in age and the degree of tumor spread. It is shown that late results of the treatment in breast cancer patients operated under fluothane narcosis are much better than those under ether narcosis.
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PMID:[Types of anesthesia and the late results of breast cancer treatment]. 59 13

Ureteroscopy via the transurethral route and limited to the terminal ureter in women lends itself to inclusion in the urological armamentarium. The technique requires no equipment other than routine urological instruments and makes endoscopic inspection, biopsy and resection within the distal ureter possible. The procedure is done with the patient under anesthesia, following urethral dilation to 32F. With the aid of a small caliber cystoscope, 20F or smaller, straight Jewett sounds can be passed into the urethra alongside the cystoscope and directed under cystoscopic control into the ureteral orifice. The orifice is then dilated gently, using 12, 14 and, if necessary, 16F sounds. One of the standard pediatric cystoscopes can then be introduced easily into the orifice. Currently, the technique is being used routinely in women with transitional cell carcinoma involving the ureteral orifice or intramural ureter. In 1 patient a tumor arising from within the lower ureter was resected successfully using a pediatric resectoscope.
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PMID:Transurethral ureteroscopy in women: a ready addition to the urological armamentarium. 62 8

A case of pituitary adenoma operated on under hemodialysis was reported. The patient was a 43-year-old male who had been obliged to hemodialysis since April 1975 because of chronic renal failure. He was admitted in February 21, 1976 because of progressive visual symptoms. Neurological examination revealed decreased visual acuity and bitemporal hemianopsia. Radiology showed enlarged sella turcica and calcified mass in the suprasellar region. Laboratory examination disclosed severe anemia and the operation was postponed until the hematocrit improved up to 39% by blood transfusion. The operation was performed in March 17, 1976 under conventional GOF anesthesia. The tumor was covered by a calcified capsule and after nibbling off the calcified covering, the tumor was removed. Postoperative course was uneventful. Peritoneal dialysis was continued for three days immediately after operation. Urinary volume of the patient increased up to 600 ml per day after operation, probably due to the postoperative diabetes insipidus. The diabetes insipidus was rather favorable sequela in this case because the patient was released from the severe restriction of water intake.
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PMID:[Intracranial surgery under hemodialysis (author's transl)]. 63 44

C57B1/6 mice were given intravenous tumor cells on day O. Mice were then given either a brief exposure to halothane anesthesia or given halothane and then underwent a hind limb amputation. Immune testing was done at varying time intervals and correlated with the development of artificial pulmonary metastases. The effects of a single 15 minute exposure to halothane on the immune system are probably short-lived and no effect on cell-mediated cytotoxicity was seen on day 7, nor was an increase in pulmonary metastases observed. However, when anesthesia was combined with surgery, cell-mediated cytotoxicity was impaired and an increase in pulmonary metastases was seen. The use of thiabendazole (TBZ), an nonspecific immunopotentiator, in the perioperative period restored the cell-mediated cytotoxic response and resulted in a significant decrease in pulmonary metastases.
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PMID:Halothane, surgery, immunosuppression and artificial pulmonary metastases. 63 70


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