Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0027651 (tumor)
 685,946 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases of gastric leiomyoblastoma (one of which of exceptional size, measuring more than 40 cm) observed respectively in 1992 at the Surgery Division of USSL 45 at Asola (MN) and in 1990 at the Second Surgery Division of USSL 47 in Mantova are reported. In the first case anaemia revealed the tumor whereas in the second case the patient suffering from a pain in the abdomen was admitted to hospital. These two tumors raise interest for their rarity and for their uncertain biological evolution. They generally develop very slowly and tend to remain intramural. The most frequently attacked seats are the antum-pyloric region and the stomach body. The main symptoms are epigastric pain, nausea, vomiting, weight loss, sideropenic anaemia, epigastric palpable mass. The diagnostic iter includes radiologic examination (digestive tube X-ray, echography, TAC, arteriography), gastroscopy and laparoscopy. In most cases surgical resection is not completely destroying, except for those cases in which the tumor measures more than 5 cm and total or subtotal gastrectomy is performed.
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PMID:[Gastric leiomyoblastoma. Two case reports]. 853 6

We report a pancreatic endocrine tumor arising within an otherwise benign pancreatic serous cystadenoma in a 47-year-old woman with a history of lupus treated by steroids. She presented 10 years before resection with epigastric pain and intermittent jaundice. Histologic and immunohistochemical studies showed that the solid endocrine component was composed of small, uniform cells with stippled nuclei, which were chromogranin A positive. The surrounding cystic component was lined by periodic acid Schiff's-positive, diastase-digestible cells containing glycogen. To the best of our knowledge, this is the first case of a serous cystadenoma of the pancreas that contains a well defined pancreatic endocrine tumor reported in the English literature.
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PMID:A pancreatic endocrine tumor arising within a serous cystadenoma of the pancreas. 860 14

Dysphagia is an unusual presenting symptom as of extradigestive tumors. Malignant mesothelioma, is a rare tumor localized in the pleural cavity in 80% of all cases and it rarely appears with dysphagia as first symptom. We describe the case of a 74-year-old woman admitted with progressive dysphagia for solid and liquid food, atypical epigastric pain, with in conclusive endoscopic and radiologic studies. Nuclear Magnetic Resonance established the diagnostic suspicion of malignant mesothelioma which was confirmed by the histologic study of a biopsy taken by thoracotomy. We think of interest to report this case of paraesophageal mesothelioma because of its unusual localization and presentation.
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PMID:[Dysphagia as an unusual form of presentation of malignant pleural mesothelioma]. 864 17

A rare case of primary jejunal malignant mixed tumor arising in a 49-64-old Japanese male with von Recklinghausen's disease is reported. The patient, who had a past history of partial gastrectomy due to duodenal ulcer, was admitted with a complaint of epigastric pain. Upper gastrointestinal examinations showed a huge polypoid tumor located in the efferent loop of the gastrojejunostomy site. Because the tumor was strongly suggestive of leiomyosarcoma on histological examination of biopsy specimens, laparotomy was performed. The resected tumor measuring 10 X 7 X 7 cm was composed of adenocarcinoma admixed with various sarcomatous components, including rhabdomyosarcoma, osteosarcoma, and other sarcomas. Immunohistochemical analysis also supported this diagnosis. The features of this tumor closely resembled malignant mixed mullerian tumor of heterologous type that develops in female genital organs. It is well known that patients with von Recklinghausen neurofibromatosis have an increased incidence of mesenchymal tumors and malignant neoplasias, and therefore, it seems that there is a possible relationship between the histogenesis of this peculiar tumor and the genetic abnormality in this patient.
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PMID:Primary jejunal malignant mixed tumor in a patient with von Recklinghausen neurofibromatosis. 867 54

A rare case of a bronchogenic cyst of the diaphragm was reported. The patient was a 56-year-old woman complaining of epigastric pain. A CT scan and a MRI examination revealed a cystic tumor at the left vertebro-phrenic angle. The cyst ruptured into the left pleural cavity causing chest pain and consequently reducing its size. As the cyst had enlarged again after 6 months, she received surgical treatment and the tumor was totally removed. The cyst was monolocular, originating from the diaphragm and proved to be bronchogenic cyst. It had bronchial epithelium, smooth muscle, bronchial gland and cartilage histologically. Japanese literature on the bronchogenic cysts of the diaphragm were discussed. Seven cases, including this case, of bronchogenic cysts of the diaphragm have been reported in Japan. It is rare for bronchogenic cysts to rupture into the pleural cavity.
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PMID:[A case report of a bronchogenic cyst of the diaphragm causing rupturing into the left pleural cavity]. 871 72

A 34-year-old woman with signs and symptoms of an acute abdomen was found to have a hepatic cyst on NMR- and CT-scan. With the tentative diagnosis of a liver hematoma, a right hemihepatectomy was performed. Histologically, an endometrial cyst of the liver was found. A second case of cystic endometriosis in the liver was revealed ultrasonographically in a 62-year-old woman, complaining of rightsided epigastrical pain. A 28-year-old woman was admitted to the hospital because of recurrent epigastric pain. A cystic tumor of the pancreas could be visualized ultrasonographically and was interpreted as a postinflammatory pseudocyst. Histological examination of the distal pancreatectomy specimen revealed cystic endometriosis. The clinicopathological features of hepatic and pancreatic endometriosis are discussed and the literature concerning these extremely rare lesions is reviewed.
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PMID:Cystic endometriosis of the upper abdominal organs. Report on three cases and review of the literature. 873 77

The present report describes a case of a 27 year old patient with epigastric pain of moderate intensity, accompanied by hiporexia, weight loss and melena who was hospitalized in August 1.994 after 17 days of these signs and symptoms. Colonoscopy revelead a 6 cms polypoid, ulcerated lesion in the hepatic angle of the colon. At surgery, a 5 x 5 cms tumoral lesional 1.5 cms from the Treitz adhered to the small bowel was found. The gross findings of the specimen revealed an exophitic ulcerated tumor that measured 10 x 10 x 9 cms. Satellite nodules up to 2 cms in diameter were seen in contact with the large bowel mucosae. Light microscopy, immunohistochemical and ultrastructural studies, indicated a diagnosis of PLEXOSARCOMA.
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PMID:[Gastrointestinal stromal sarcoma. Report of a case and review of the literature]. 876 63

We reported a very rare case of hepatocellular carcinoma (HCC) developed in a normal liver without persistent hepatitis B or C virus (HBV or HCV) infection. A 39-year-old woman was admitted to our hospital for epigastralgia. Laboratory data demonstrated normal liver function and she had no evidence of past and persistent HBV or HCV infection. Abdominal ultrasonography and abdominal CT scan demonstrated liver tumor of about 40 mm in maximal diameter in the lateral segment. This tumor was moderately differentiated hepatocellular carcinoma (HCC) from the result of operative sample, and the non-tumor area surrounding the HCC was normal pathological finding. The potential integration of HBV DNA into tumor or non tumor cells was not observed. This is a very rare case of hepatocellular carcinoma developed in a normal liver without HBV and HCV infection.
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PMID:A case of hepatocellular carcinoma in normal liver with no evidence of HBV or HCV infection. 890 80

A 52-year-old man with rectal cancer and liver metastasis underwent tumor resection with hepatic arterial catheterization. During adjuvant chemotherapy, he developed epigastric pain, nausea, and melena. Digital subtraction angiography revealed a hepatic artery-biliary fistula and a pseudoaneurysm at the catheter tip. This rare complication of intra-arterial chemotherapy is reported in detail.
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PMID:Hepatic artery-biliary fistula during infusion chemotherapy. 890 79

Tuberculous mesenteric lymphadenitis is a rare clinical entity and non-surgical diagnosis of this condition remains a challenge. A 38-year-old Indian woman presented with a six-week history of epigastric pain, low-grade fever and anorexia. Upper endoscopy showed a gastric ulcer of the posterior wall of the stomach. On CT scan there was a 8 cm abdominal mass involving the pancreatic body and tail and the endoscopic ultrasonography was also compatible with a cystic pancreatic tumor which had eroded into the stomach. An exploratory laparotomy was performed and the diagnosis of tuberculous mesenteric lymphadenitis was confirmed by bacteriological and histological examinations. Medical therapy was started after surgery. At 18 months she is asymptomatic and abdominal CT scan is normal. Tuberculosis of mesenteric lymph nodes usually raises serious diagnostic problems. A high grade of suspicion is necessary in order to perform a pre-operative diagnosis.
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PMID:Tuberculous mesenteric lymphadenitis mimicking pancreatic carcinoma. 897 83


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